KEGG   Homo sapiens (human): 970
Entry
970               CDS       T01001                                 
Symbol
CD70, CD27-L, CD27L, CD27LG, LPFS3, TNFSF7, TNLG8A
Name
(RefSeq) CD70 molecule
  KO
K05470  tumor necrosis factor ligand superfamily member 7
Organism
hsa  Homo sapiens (human)
Pathway
hsa04060  Cytokine-cytokine receptor interaction
Network
nt06516  TNF signaling
  Element
N01799  CD70-CD27 signaling pathway
Disease
H01970  Lymphoproliferative syndrome
Drug target
Vorsetuzumab: D10342
Vorsetuzumab mafodotin: D10341
Brite
KEGG Orthology (KO) [BR:hsa00001]
 09130 Environmental Information Processing
  09133 Signaling molecules and interaction
   04060 Cytokine-cytokine receptor interaction
    970 (CD70)
 09180 Brite Hierarchies
  09183 Protein families: signaling and cellular processes
   04052 Cytokines and neuropeptides [BR:hsa04052]
    970 (CD70)
   04090 CD molecules [BR:hsa04090]
    970 (CD70)
Cytokines and neuropeptides [BR:hsa04052]
 Cytokines
  Tumor necrosis fators
   970 (CD70)
CD molecules [BR:hsa04090]
 Proteins
  970 (CD70)
SSDB
Motif
Pfam: TNF
Other DBs
NCBI-GeneID: 970
NCBI-ProteinID: NP_001243
OMIM: 602840
HGNC: 11937
Ensembl: ENSG00000125726
UniProt: P32970 A0A0U5JA32
Structure
LinkDB
Position
19:complement(6581648..6591150)
AA seq 193 aa
MPEEGSGCSVRRRPYGCVLRAALVPLVAGLVICLVVCIQRFAQAQQQLPLESLGWDVAEL
QLNHTGPQQDPRLYWQGGPALGRSFLHGPELDKGQLRIHRDGIYMVHIQVTLAICSSTTA
SRHHPTTLAVGICSPASRSISLLRLSFHQGCTIASQRLTPLARGDTLCTNLTGTLLPSRN
TDETFFGVQWVRP
NT seq 582 nt   +upstreamnt  +downstreamnt
atgccggaggagggttcgggctgctcggtgcggcgcaggccctatgggtgcgtcctgcgg
gctgctttggtcccattggtcgcgggcttggtgatctgcctcgtggtgtgcatccagcgc
ttcgcacaggctcagcagcagctgccgctcgagtcacttgggtgggacgtagctgagctg
cagctgaatcacacaggacctcagcaggaccccaggctatactggcaggggggcccagca
ctgggccgctccttcctgcatggaccagagctggacaaggggcagctacgtatccatcgt
gatggcatctacatggtacacatccaggtgacgctggccatctgctcctccacgacggcc
tccaggcaccaccccaccaccctggccgtgggaatctgctctcccgcctcccgtagcatc
agcctgctgcgtctcagcttccaccaaggttgtaccattgcctcccagcgcctgacgccc
ctggcccgaggggacacactctgcaccaacctcactgggacacttttgccttcccgaaac
actgatgagaccttctttggagtgcagtgggtgcgcccctga

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