Homo sapiens (human): 9771
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Entry
9771 CDS
T01001
Symbol
RAPGEF5, GFR, MR-GEF, MRGEF, REPAC
Name
(RefSeq) Rap guanine nucleotide exchange factor 5
KO
K08019
Rap guanine nucleotide exchange factor 5
Organism
hsa
Homo sapiens (human)
Pathway
hsa04014
Ras signaling pathway
hsa04015
Rap1 signaling pathway
Brite
KEGG Orthology (KO) [BR:
hsa00001
]
09130 Environmental Information Processing
09132 Signal transduction
04014 Ras signaling pathway
9771 (RAPGEF5)
04015 Rap1 signaling pathway
9771 (RAPGEF5)
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GFIT
Motif
Pfam:
RasGEF
RasGEF_N
RA
RA_2
SNX17-27-31_F1_FERM
Motif
Other DBs
NCBI-GeneID:
9771
NCBI-ProteinID:
NP_001354529
OMIM:
609527
HGNC:
16862
Ensembl:
ENSG00000136237
UniProt:
Q92565
A0A0S2Z561
Structure
PDB
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Position
7:complement(22118236..22357154)
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AA seq
580 aa
AA seq
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MGSSRLRVFDPHLERKDSAAALSDRELPLPTFDVPYFKYIDEEDEDDEWSSRSQSSTEDD
SVDSLLSDRYVVVSGTPEKILEHLLNDLHLEEVQDKETETLLDDFLLTYTVFMTTDDLCQ
ALLRHYSAKKYQGKEENSDVPRRKRKVLHLVSQWIALYKDWLPEDEHSKMFLKTIYRNVL
DDVYEYPILEKELKEFQKILGMHRRHTVDEYSPQKKNKALFHQFSLKENWLQHRGTVTET
EEIFCHVYITEHSYVSVKAKVSSIAQEILKVVAEKIQYAEEDLALVAITFSGEKHELQPN
DLVISKSLEASGRIYVYRKDLADTLNPFAENEESQQRSMRILGMNTWDLALELMNFDWSL
FNSIHEQELIYFTFSRQGSGEHTANLSLLLQRCNEVQLWVATEILLCSQLGKRVQLVKKF
IKIAAHCKAQRNLNSFFAIVMGLNTASVSRLSQTWEKIPGKFKKLFSELESLTDPSLNHK
AYRDAFKKMKPPKIPFMPLLLKDVTFIHEGNKTFLDNLVNFEKLHMIADTVRTLRHCRTN
QFGDLSPKEHQELKSYVNHLYVIDSQQALFELSHRIEPRV
NT seq
1743 nt
NT seq
+upstream
nt +downstream
nt
atgggcagctcccggctgagggtctttgaccctcatttggagaggaaagattccgccgcg
gcgctctcagaccgagagctgcccttgcctaccttcgatgtgccttatttcaaatacatc
gacgaggaggatgaggacgatgaatggagcagccgctcgcagtcttccaccgaggatgac
tcagtggactctctgctctctgacagatatgtggtggtgtccgggaccccggagaagatt
ttggagcaccttttgaatgacttgcacctggaagaagtccaggacaaagaaacagagacc
ctcctggatgacttccttctcacgtacactgtcttcatgacaactgatgacttgtgccag
gctctgttaaggcactattctgctaagaagtatcaaggcaaagaggaaaactcagacgtt
ccgcgtaggaaacgtaaagtcttgcatcttgtttcccagtggattgctctgtacaaagac
tggttacctgaagatgaacattcaaaaatgtttttaaagaccatatataggaatgtactg
gatgatgtttatgaatatccaatacttgaaaaagaattgaaagaatttcaaaagatactt
ggaatgcaccgtcgtcacactgtagatgaatattcaccacaaaaaaagaataaagccctt
ttccaccaattcagtcttaaggagaactggctccagcatagaggaactgtgactgaaacg
gaggaaattttctgccacgtgtatataacagagcactcctatgtcagtgtgaaggcaaaa
gtttccagtatagcccaagagatcctaaaagtcgtggcagaaaagatccagtatgcagaa
gaggatctggctctggtggccatcacattctctggggaaaagcatgaacttcagccaaat
gacttagtcatctccaaatccctcgaggcatctggtcgaatatatgtctaccggaaagac
ctggcggacactttgaacccatttgcagaaaatgaggaatcacagcaaaggtcgatgagg
attttgggaatgaacacttgggatcttgctctggaattaatgaattttgattggagtcta
ttcaattcaattcacgagcaagagctgatctacttcacgttcagcagacagggaagtggg
gaacacactgcaaatctcagccttctgctccagagatgcaatgaggtccagctttgggtg
gccacggagattctgctctgcagccagctgggcaagcgagtgcagctggtgaaaaaattc
atcaaaattgcggctcactgcaaagcccagagaaacctgaattctttctttgccattgtg
atgggtctcaacactgcttctgtcagtcgactgtcgcagacctgggagaaaatccctggg
aagtttaagaaacttttctctgaacttgaaagtttaacagatccttccctaaatcacaaa
gcctacagagatgcattcaaaaagatgaagccaccaaaaatccctttcatgcccttattg
cttaaagatgtaacatttattcatgaaggaaataaaacttttttggataatcttgtcaat
tttgaaaagctgcatatgatcgcagacactgtccgaaccctgagacactgcaggactaac
cagtttggtgacctgtctccaaaagagcatcaagagttaaagtcctatgttaatcacctg
tatgtcattgacagccagcaggctctgtttgagctctcacacaggatcgagcctcgggtg
tga
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