Homo sapiens (human): 9771
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Entry
9771 CDS
T01001
Symbol
RAPGEF5, GFR, MR-GEF, MRGEF, REPAC
Name
(RefSeq) Rap guanine nucleotide exchange factor 5
KO
K08019
Rap guanine nucleotide exchange factor 5
Organism
hsa
Homo sapiens (human)
Pathway
hsa04014
Ras signaling pathway
hsa04015
Rap1 signaling pathway
Brite
KEGG Orthology (KO) [BR:
hsa00001
]
09130 Environmental Information Processing
09132 Signal transduction
04014 Ras signaling pathway
9771 (RAPGEF5)
04015 Rap1 signaling pathway
9771 (RAPGEF5)
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Gene cluster
GFIT
Motif
Pfam:
RasGEF
DEP
RasGEF_N
DUF6382
RA
RA_2
SNX17-27-31_F1_FERM
Motif
Other DBs
NCBI-GeneID:
9771
NCBI-ProteinID:
NP_036426
OMIM:
609527
HGNC:
16862
Ensembl:
ENSG00000136237
UniProt:
Q92565
Q5JPD2
A8MQ07
Structure
PDB
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All DBs
Position
7:complement(22118236..22357154)
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AA seq
883 aa
AA seq
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MRMAVGSVKMQPPCESPALAAAAAVVAADGPLRRSPSAREPEREQPPASLRPRLRDLPAL
LRSGLTLRRKRSAAGGRTLSRRISNPYLEHTPSQIYGENSSCAGRALRNIIIVQAADLIK
DRVNLKGFYRRSCVGSELVDWLLEHCPFVQCRSMAIGVWQLLLDMGIMLSVDQHLYFQDT
YVFYQFSSDECSYLYCEFEREEEWQNGVKLLLQLVPLIPARGGICELSHQKIEDSEESSD
EILVRLTSAVQRELAAVIALKARKSAIEQDEENNDKHVAVTEAESVPDSQAGVMCKLQER
DEIGRIELVQKLAKENYQFLQTDKKEQEKSEHQDDEVTTVQVKEQDQSVLVLKKVQCCGP
APTAGSAESHWRYVVVSGTPEKILEHLLNDLHLEEVQDKETETLLDDFLLTYTVFMTTDD
LCQALLRHYSAKKYQGKEENSDVPRRKRKVLHLVSQWIALYKDWLPEDEHSKMFLKTIYR
NVLDDVYEYPILEKELKEFQKILGMHRRHTVDEYSPQKKNKALFHQFSLKENWLQHRGTV
TETEEIFCHVYITEHSYVSVKAKVSSIAQEILKVVAEKIQYAEEDLALVAITFSGEKHEL
QPNDLVISKSLEASGRIYVYRKDLADTLNPFAENEESQQRSMRILGMNTWDLALELMNFD
WSLFNSIHEQELIYFTFSRQGSGEHTANLSLLLQRCNEVQLWVATEILLCSQLGKRVQLV
KKFIKIAAHCKAQRNLNSFFAIVMGLNTASVSRLSQTWEKIPGKFKKLFSELESLTDPSL
NHKAYRDAFKKMKPPKIPFMPLLLKDVTFIHEGNKTFLDNLVNFEKLHMIADTVRTLRHC
RTNQFGDLSPKEHQELKSYVNHLYVIDSQQALFELSHRIEPRV
NT seq
2652 nt
NT seq
+upstream
nt +downstream
nt
atgaggatggccgtgggctccgtcaagatgcagccgccgtgcgagagcccggccctggcc
gccgcggcggcggtggtggcggcagacggccccctgcgccgcagccccagcgcccgggag
cccgagcgcgagcagccgccggcgtcgctgcggccgcggctgagggacctgcccgcgctg
ctgcggagcgggctcacgctgcggaggaagcggagcgccgctgggggccggactctatca
agaagaatatctaatccgtaccttgaacatacgccttcccagatttatggagagaattct
tcttgtgcaggaagagcattgaggaatattattatcgttcaagcagctgacctgataaag
gacagagtgaacctcaaggggttttacaggaggagctgcgttgggtcagagctggtagac
tggcttctagaacactgtcctttcgtccagtgcagatctatggccataggagtctggcaa
ctcctactggacatgggaattatgttatcagtggaccagcatctatactttcaagatact
tatgttttctaccagttttcctctgatgaatgtagctacttgtactgtgaatttgaaaga
gaagaagaatggcaaaatggtgtcaagcttttactgcaacttgtgcctctcattcctgcc
agaggtggcatctgtgaactgtctcatcagaaaattgaagactccgaagaaagcagtgat
gaaattcttgtgcgtctaacatctgcggtgcagagagagctagcagctgttattgctttg
aaagcaaggaagtctgcaattgaacaagatgaagaaaacaacgacaaacatgtagctgta
acagaagccgaaagtgttccagattctcaggcaggggtgatgtgcaagctccaggaaaga
gatgaaatcggacgaattgaactagtccagaagctggcaaaagaaaactatcagtttttg
cagacggacaaaaaagaacaggagaagtctgaacaccaagatgatgaagtgacgactgtt
caggttaaagagcaagaccagagcgtcctggtgctgaagaaagtgcagtgctgtggccca
gcccccacagctgggagtgcggagagccattggagatatgtggtggtgtccgggaccccg
gagaagattttggagcaccttttgaatgacttgcacctggaagaagtccaggacaaagaa
acagagaccctcctggatgacttccttctcacgtacactgtcttcatgacaactgatgac
ttgtgccaggctctgttaaggcactattctgctaagaagtatcaaggcaaagaggaaaac
tcagacgttccgcgtaggaaacgtaaagtcttgcatcttgtttcccagtggattgctctg
tacaaagactggttacctgaagatgaacattcaaaaatgtttttaaagaccatatatagg
aatgtactggatgatgtttatgaatatccaatacttgaaaaagaattgaaagaatttcaa
aagatacttggaatgcaccgtcgtcacactgtagatgaatattcaccacaaaaaaagaat
aaagcccttttccaccaattcagtcttaaggagaactggctccagcatagaggaactgtg
actgaaacggaggaaattttctgccacgtgtatataacagagcactcctatgtcagtgtg
aaggcaaaagtttccagtatagcccaagagatcctaaaagtcgtggcagaaaagatccag
tatgcagaagaggatctggctctggtggccatcacattctctggggaaaagcatgaactt
cagccaaatgacttagtcatctccaaatccctcgaggcatctggtcgaatatatgtctac
cggaaagacctggcggacactttgaacccatttgcagaaaatgaggaatcacagcaaagg
tcgatgaggattttgggaatgaacacttgggatcttgctctggaattaatgaattttgat
tggagtctattcaattcaattcacgagcaagagctgatctacttcacgttcagcagacag
ggaagtggggaacacactgcaaatctcagccttctgctccagagatgcaatgaggtccag
ctttgggtggccacggagattctgctctgcagccagctgggcaagcgagtgcagctggtg
aaaaaattcatcaaaattgcggctcactgcaaagcccagagaaacctgaattctttcttt
gccattgtgatgggtctcaacactgcttctgtcagtcgactgtcgcagacctgggagaaa
atccctgggaagtttaagaaacttttctctgaacttgaaagtttaacagatccttcccta
aatcacaaagcctacagagatgcattcaaaaagatgaagccaccaaaaatccctttcatg
cccttattgcttaaagatgtaacatttattcatgaaggaaataaaacttttttggataat
cttgtcaattttgaaaagctgcatatgatcgcagacactgtccgaaccctgagacactgc
aggactaaccagtttggtgacctgtctccaaaagagcatcaagagttaaagtcctatgtt
aatcacctgtatgtcattgacagccagcaggctctgtttgagctctcacacaggatcgag
cctcgggtgtga
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