KEGG   ORTHOLOGY: K08019
Entry
K08019                      KO                                     
Symbol
RAPGEF5
Name
Rap guanine nucleotide exchange factor 5
Pathway
map04014  Ras signaling pathway
map04015  Rap1 signaling pathway
Brite
KEGG Orthology (KO) [BR:ko00001]
 09130 Environmental Information Processing
  09132 Signal transduction
   04014 Ras signaling pathway
    K08019  RAPGEF5; Rap guanine nucleotide exchange factor 5
   04015 Rap1 signaling pathway
    K08019  RAPGEF5; Rap guanine nucleotide exchange factor 5
Genes
HSA: 9771(RAPGEF5)
PTR: 463284(RAPGEF5)
PPS: 100975268(RAPGEF5)
GGO: 101150356(RAPGEF5)
PON: 100455766(RAPGEF5)
PPYG: 129040453(RAPGEF5)
NLE: 100585636(RAPGEF5)
HMH: 116813204(RAPGEF5)
SSYN: 129479411(RAPGEF5)
MCC: 711698(RAPGEF5)
MCF: 102140481(RAPGEF5)
MTHB: 126950012
MNI: 105475677(RAPGEF5)
CSAB: 103226392(RAPGEF5)
CATY: 105595373(RAPGEF5)
PANU: 101011973(RAPGEF5)
TGE: 112621139(RAPGEF5)
MLEU: 105534983(RAPGEF5)
RRO: 104675266(RAPGEF5)
RBB: 108529323(RAPGEF5)
TFN: 117072401(RAPGEF5)
PTEH: 111545096(RAPGEF5)
CANG: 105513328(RAPGEF5)
CJC: 100394511(RAPGEF5)
SBQ: 101033510(RAPGEF5)
CIMI: 108303196(RAPGEF5)
ANAN: 105713959(RAPGEF5)
CSYR: 103249249(RAPGEF5)
MMUR: 105875880(RAPGEF5)
LCAT: 123647122(RAPGEF5)
PCOQ: 105822458(RAPGEF5)
OGA: 100948610(RAPGEF5)
MMU: 217944(Rapgef5)
MCAL: 110307233(Rapgef5)
MPAH: 110324297(Rapgef5)
RNO: 362799(Rapgef5)
MCOC: 116080810(Rapgef5)
ANU: 117697248(Rapgef5)
MUN: 110551808(Rapgef5)
CGE: 100769866(Rapgef5)
MAUA: 101844234(Rapgef5)
PROB: 127216939(Rapgef5)
PLEU: 114701027(Rapgef5)
MORG: 121438453(Rapgef5)
MFOT: 126487824
AAMP: 119819314(Rapgef5)
NGI: 103740776(Rapgef5)
HGL: 101700232(Rapgef5)
CPOC: 100733128(Rapgef5)
CCAN: 109695145(Rapgef5)
DORD: 105991406(Rapgef5)
DSP: 122112132(Rapgef5)
PLOP: 125346829(Rapgef5)
NCAR: 124991215
MMMA: 107152635(Rapgef5)
OCU: 100337732
OPI: 101522863(RAPGEF5)
TUP: 102497002(RAPGEF5)
GVR: 103604366(RAPGEF5)
CFA: 100855786(RAPGEF5)
CLUD: 112670560(RAPGEF5)
VVP: 112915725(RAPGEF5)
VLG: 121474513(RAPGEF5)
NPO: 129502769(RAPGEF5)
AML: 100472289(RAPGEF5)
UMR: 103659043(RAPGEF5)
UAH: 113261264(RAPGEF5)
UAR: 123789183(RAPGEF5)
ELK: 111147241
LLV: 125080637
MPUF: 101672197(RAPGEF5)
MNP: 132015887(RAPGEF5)
MLK: 131829491(RAPGEF5)
NVS: 122904893(RAPGEF5)
ORO: 101377575(RAPGEF5)
EJU: 114221233(RAPGEF5)
ZCA: 113911558(RAPGEF5)
MLX: 118020855(RAPGEF5)
NSU: 110579909(RAPGEF5)
LWW: 102745590(RAPGEF5)
FCA: 101088478(RAPGEF5)
PYU: 121028637(RAPGEF5)
PCOO: 112866765(RAPGEF5)
PBG: 122487986(RAPGEF5)
PVIV: 125152157(RAPGEF5)
LRUF: 124524853
PTG: 102960844(RAPGEF5)
PPAD: 109263812(RAPGEF5)
PUC: 125930825
AJU: 106982264
HHV: 120236212(RAPGEF5)
BTA: 519566(RAPGEF5)
BOM: 102287340(RAPGEF5)
BIU: 109557298(RAPGEF5)
BBUB: 102416417(RAPGEF5)
BBIS: 104987932(RAPGEF5)
CHX: 102169728(RAPGEF5)
OAS: 101108303(RAPGEF5)
BTAX: 128046597(RAPGEF5)
ODA: 120878069(RAPGEF5)
CCAD: 122438194(RAPGEF5)
MBEZ: 129552297(RAPGEF5)
SSC: 100518983(RAPGEF5)
CFR: 102511297(RAPGEF5)
CBAI: 105079799(RAPGEF5)
CDK: 105092902(RAPGEF5)
VPC: 102529211(RAPGEF5)
BACU: 103008073(RAPGEF5)
BMUS: 118900742(RAPGEF5)
LVE: 103081274(RAPGEF5)
OOR: 101282025(RAPGEF5)
DLE: 111181969(RAPGEF5)
PCAD: 102980427(RAPGEF5)
PSIU: 116759780(RAPGEF5)
NASI: 112395352(RAPGEF5)
ECB: 100067593(RAPGEF5)
EPZ: 103561104(RAPGEF5)
EAI: 106824351(RAPGEF5)
MYB: 102243853(RAPGEF5)
MYD: 102755260(RAPGEF5)
MMYO: 118666135(RAPGEF5)
MLF: 102432406(RAPGEF5)
MDT: 132243027(RAPGEF5)
PKL: 118714204(RAPGEF5)
EFUS: 103294502(RAPGEF5)
MNA: 107540317(RAPGEF5)
DRO: 112306872(RAPGEF5)
AJM: 119042547(RAPGEF5)
PDIC: 114508151(RAPGEF5)
PHAS: 123811479(RAPGEF5)
MMF: 118620430(RAPGEF5)
PPAM: 129063126(RAPGEF5)
HAI: 109387865(RAPGEF5)
RFQ: 117012263(RAPGEF5)
PALE: 102895332(RAPGEF5)
PGIG: 120602330(RAPGEF5)
PVP: 105293148(RAPGEF5)
RAY: 107518119(RAPGEF5)
MJV: 108403513(RAPGEF5)
TOD: 119243280(RAPGEF5)
SARA: 101545205(RAPGEF5)
SETR: 126025574(RAPGEF5)
LAV: 100655532(RAPGEF5)
TMU: 101356550
DNM: 101430239(RAPGEF5)
MDO: 100016990(RAPGEF5)
GAS: 123248803(RAPGEF5)
SHR: 100930457(RAPGEF5)
AFZ: 127564693
PCW: 110213022(RAPGEF5)
TVP: 118850383(RAPGEF5)
OAA: 100083319(RAPGEF5)
GGA: 100857462(RAPGEF5)
PCOC: 116227027(RAPGEF5)
MGP: 100548290(RAPGEF5)
CJO: 107309176(RAPGEF5)
TPAI: 128085820(RAPGEF5)
LMUT: 125695715(RAPGEF5)
NMEL: 110393264(RAPGEF5)
APLA: 101797966(RAPGEF5)
ACYG: 106030191(RAPGEF5)
CATA: 118255913(RAPGEF5)
AFUL: 116485711(RAPGEF5)
TGU: 100223599(RAPGEF5)
LSR: 110474664(RAPGEF5)
SCAN: 103813130(RAPGEF5)
PMOA: 120499705(RAPGEF5)
OTC: 121343239(RAPGEF5)
PRUF: 121352853(RAPGEF5)
GFR: 102035122(RAPGEF5)
FAB: 101806736(RAPGEF5)
OMA: 130249199(RAPGEF5)
PHI: 102109344(RAPGEF5)
PMAJ: 107200142(RAPGEF5)
CCAE: 111924414
CCW: 104689317(RAPGEF5)
CBRC: 103613554
ETL: 114063453(RAPGEF5)
ZAB: 102067352(RAPGEF5)
ZLE: 135443800(RAPGEF5)
ACHL: 103811888(RAPGEF5)
SVG: 106863985(RAPGEF5)
MMEA: 130572152(RAPGEF5)
HRT: 120765858(RAPGEF5)
SATI: 136360980(RAPGEF5)
FPG: 101913941(RAPGEF5)
FCH: 102060125
CCRI: 104168604(RAPGEF5)
NNT: 104402238(RAPGEF5)
SHAB: 115608180(RAPGEF5)
ACUN: 113477016
TALA: 104369301(RAPGEF5)
ACHC: 115339065(RAPGEF5)
HALD: 104316817(RAPGEF5)
HLE: 104838076(RAPGEF5)
AGEN: 126037994
GCL: 127012967
CSTI: 104562525(RAPGEF5)
LDI: 104345913(RAPGEF5)
MNB: 103780100(RAPGEF5)
DPUB: 104297611
AVIT: 104268399(RAPGEF5)
BRHI: 104501522
EGZ: 104126109(RAPGEF5)
NNI: 104013986(RAPGEF5)
PCRI: 104029351(RAPGEF5)
PCAO: 104044334(RAPGEF5)
PADL: 103918453 103918454
AFOR: 103901236
FGA: 104081019(RAPGEF5)
GSTE: 104260383(RAPGEF5)
CLV: 102097426(RAPGEF5)
PGUU: 104461490(RAPGEF5)
PLET: 104625440(RAPGEF5)
EHS: 104514025(RAPGEF5)
CMAC: 104486544(RAPGEF5)
CUCA: 104068042(RAPGEF5)
TEO: 104377489(RAPGEF5)
OHA: 104326586(RAPGEF5)
ACAR: 104529598(RAPGEF5)
CPEA: 104397656
CVF: 104281558
RTD: 128905285(RAPGEF5)
AAM: 106483537(RAPGEF5)
AROW: 112977952(RAPGEF5)
NPD: 112942404
TGT: 104577441(RAPGEF5)
DNE: 112986000(RAPGEF5)
SCAM: 104146059
ASN: 102376298(RAPGEF5)
AMJ: 102572070(RAPGEF5)
CPOO: 109309664(RAPGEF5)
GGN: 109291520(RAPGEF5)
PSS: 102463791(RAPGEF5)
CMY: 102936146(RAPGEF5)
CCAY: 125631519(RAPGEF5)
DCC: 119851071(RAPGEF5)
CPIC: 101951052(RAPGEF5)
TST: 117872294(RAPGEF5)
CABI: 116826587(RAPGEF5)
MRV: 120398585(RAPGEF5)
ACS: 100567077(rapgef5)
ASAO: 132778779(RAPGEF5)
PVT: 110072674(RAPGEF5)
SUND: 121934682(RAPGEF5)
PBI: 103056016(RAPGEF5)
PMUR: 107282971(RAPGEF5)
CTIG: 120307376(RAPGEF5)
TSR: 106540096(RAPGEF5)
PGUT: 117655223(RAPGEF5)
APRI: 131197648(RAPGEF5)
PTEX: 113440159(RAPGEF5)
NSS: 113418881(RAPGEF5)
VKO: 123022596(RAPGEF5)
PMUA: 114607164(RAPGEF5)
PRAF: 128424366(RAPGEF5)
ZVI: 118091632(RAPGEF5)
HCG: 128330594(RAPGEF5)
GJA: 107116124(RAPGEF5)
STOW: 125440849(RAPGEF5)
EMC: 129337826(RAPGEF5)
XLA: 108718862(rapgef5.L) 779207(rapgef5.S)
XTR: 100494102(rapgef5)
NPR: 108799691(RAPGEF5)
RTEM: 120940132(RAPGEF5)
BBUF: 121002321(RAPGEF5)
BGAR: 122937724(RAPGEF5)
MUO: 115469271(RAPGEF5)
GSH: 117354072(RAPGEF5)
DRE: 100331732(rapgef5a)
SRX: 107710058 107714290(rapgef5) 107728526 107743169
SANH: 107667583 107674937 107685551
SGH: 107570915 107571363 107581543 107596719
CCAR: 109046231 109072204(rapgef5) 109081492 109107415
CAUA: 113060191 113071315 113080271 113116288 113119921
CGIB: 127935145 127975012 127979619 128030888
PTET: 122335203(rapgef5a) 122360329(rapgef5b)
LROH: 127178500(rapgef5b) 127181561(rapgef5a)
OMC: 131521543(rapgef5b) 131525319(rapgef5a)
PPRM: 120481289 120483402(rapgef5a)
RKG: 130069037(rapgef5a) 130070167(rapgef5b)
MAMB: 125243112(rapgef5b) 125276093(rapgef5a)
CIDE: 127497816 127501681
CERY: 137031377(rapgef5b) 137037546(rapgef5a)
MASI: 127420859 127425282 127453051 127454341
TROS: 130558287(rapgef5b) 130567228(rapgef5a)
TDW: 130415674(rapgef5a) 130432916(rapgef5b)
MANU: 129447795(rapgef5b) 129455146(rapgef5a)
IPU: 108257194(rapgef5a) 108267288(rapgef5b)
IFU: 128600206(rapgef5a) 128609160(rapgef5b)
PHYP: 113536080(rapgef5) 113542627
SMEO: 124375882(rapgef5a) 124384409
TFD: 113644428(rapgef5b) 113661485(rapgef5a)
TVC: 132845992(rapgef5b) 132864284(rapgef5a)
TRN: 134310727(rapgef5b) 134333226(rapgef5a)
AMEX: 103024308(rapgef5b) 103043785(rapgef5a)
CMAO: 118806158(rapgef5a) 118825788(rapgef5b)
EEE: 113571226 113572096(rapgef5)
CHAR: 105903649(rapgef5a) 105906319
TRU: 101064245 101078392
TFS: 130517924(rapgef5a) 130532548
TNG: GSTEN00004124G001 GSTEN00034151G001
LCO: 104922095 104926694
NCC: 104958217 104966279
TBEN: 117477796(rapgef5a) 117480466
CGOB: 115016139 115021645
PGEO: 117454918(rapgef5a) 117460457
GACU: 117554076 117562888(rapgef5a)
EMAC: 134861835 134874636(rapgef5a)
ELY: 117263934(rapgef5a) 117266262
EFO: 125893323 125905404(rapgef5a)
PLEP: 121945621 121957435(rapgef5a)
SLUC: 116049382 116067043(rapgef5a)
ECRA: 117946502 117956327(rapgef5a)
ESP: 116691439 116701269
PFLV: 114557090 114568346
GAT: 120810507 120826341(rapgef5a)
PPUG: 119197666 119219101(rapgef5a)
AFB: 129097569(rapgef5a) 129109380
CLUM: 117739401(rapgef5a) 117745406
PSWI: 130210510(rapgef5a) 130212624
MSAM: 119897761 119907126(rapgef5a)
SCHU: 122863995(rapgef5a) 122881396
CUD: 121513519 121523230
ALAT: 119006580 119016769(rapgef5a)
MZE: 101469228 101470693
ONL: 100692884 100705529
OAU: 116311999(rapgef5a) 116325412
OLA: 101158382 101166146
OML: 112136529(rapgef5a) 112143297
CSAI: 133429579 133461581(rapgef5a)
XMA: 102216758 102221249
XCO: 114141782 114156135
XHE: 116717122 116731281
PRET: 103472270 103478552
PFOR: 103135012 103150401
PLAI: 106953838(rapgef5)
PMEI: 106906000 106910074 106922215
GAF: 122831417 122843417(rapgef5a)
PPRL: 129371435 129378526(rapgef5a)
CVG: 107085890 107102477
CTUL: 119772876 119785924(rapgef5a)
GMU: 124865453 124879540(rapgef5a)
NFU: 107378679 107383628
KMR: 108241533(rapgef5a) 108242031
ALIM: 106515712 106517734
NWH: 119425770(rapgef5a)
AOCE: 111573773 111588874
MCEP: 125016785 125019844(rapgef5a)
CSEM: 103388404 103394620
POV: 109631832 109633202
SSEN: 122760634 122786533(rapgef5a)
HHIP: 117770374(rapgef5a) 117777093
HSP: 118114050 118125015(rapgef5a)
PPLT: 128449391 128461893(rapgef5a)
SMAU: 118292040(rapgef5a) 118309010
LCF: 108891185 108897814(rapgef5a)
SDU: 111222993 111238790
SLAL: 111659344 111668812
XGL: 120784236 120786673(rapgef5a)
HCQ: 109513609 109517623
SSCV: 125975535 125986846
SBIA: 133494050(rapgef5a) 133501077
PEE: 133395638(rapgef5a) 133401769
PTAO: 133470815(rapgef5a) 133479489
BPEC: 110167216 110171586
MALB: 109963966 109967255
BSPL: 114842466 114865735(rapgef5a)
SJO: 128365913 128373694(rapgef5a)
SASA: 106570585 106588797 106605879
STRU: 115173893 115184108 115184109 115186244
OTW: 112217351 112238962 112265821
OMY: 110487912 110496523 110535184 118944776
OGO: 124012252(rapgef5a) 124043175
ONE: 115117725
OKI: 109876607 109880072 109908565 116364216
OKE: 118371858 118372806 118380960
SALP: 111955759
SNH: 120022488 120048839
CCLU: 121555563 121572274 121586643 121586934
ELS: 105012468 105018831
SFM: 108927445 108933409(rapgef5)
PKI: 111846943(rapgef5) 111850409
AANG: 118231820(rapgef5b)
LOC: 102696528(rapgef5)
PSPA: 121313603(rapgef5a) 121315083
ARUT: 117399608(rapgef5a) 117435465
PSEX: 120516197(rapgef5a)
LCM: 102366211(RAPGEF5)
CMK: 103185006(rapgef5a)
RTP: 109930700(rapgef5a)
CPLA: 122549783
HOC: 132816009
LERI: 129712708(rapgef5a)
 » show all
Reference
PMID:10934204
  Authors
Rebhun JF, Castro AF, Quilliam LA
  Title
Identification of guanine nucleotide exchange factors (GEFs) for the Rap1 GTPase. Regulation of MR-GEF by M-Ras-GTP interaction.
  Journal
J Biol Chem 275:34901-8 (2000)
DOI:10.1074/jbc.M005327200
  Sequence
[hsa:9771]
LinkDB

DBGET integrated database retrieval system