Homo sapiens (human): 242
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Entry
242 CDS
T01001
Symbol
ALOX12B, 12R-LOX, ARCI2
Name
(RefSeq) arachidonate 12-lipoxygenase, 12R type
KO
K08021
arachidonate 12-lipoxygenase (R-type) [EC:1.13.11.-]
Organism
hsa
Homo sapiens (human)
Pathway
hsa00590
Arachidonic acid metabolism
hsa01100
Metabolic pathways
hsa04382
Cornified envelope formation
hsa04726
Serotonergic synapse
Network
nt06545
Cornified envelope formation
Element
N01929
Peroxidation and deglycosylation of acylglucosylceramide
Disease
H00734
Autosomal recessive congenital ichthyosis
Brite
KEGG Orthology (KO) [BR:
hsa00001
]
09100 Metabolism
09103 Lipid metabolism
00590 Arachidonic acid metabolism
242 (ALOX12B)
09150 Organismal Systems
09156 Nervous system
04726 Serotonergic synapse
242 (ALOX12B)
09158 Development and regeneration
04382 Cornified envelope formation
242 (ALOX12B)
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Ortholog
Paralog
Gene cluster
GFIT
Motif
Pfam:
Lipoxygenase
PLAT
Motif
Other DBs
NCBI-GeneID:
242
NCBI-ProteinID:
NP_001130
OMIM:
603741
HGNC:
430
Ensembl:
ENSG00000179477
UniProt:
O75342
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Position
17:complement(8072636..8087716)
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AA seq
701 aa
AA seq
DB search
MATYKVRVATGTDLLSGTRDSISLTIVGTQGESHKQLLNHFGRDFATGAVGQYTVQCPQD
LGELIIIRLHKERYAFFPKDPWYCNYVQICAPNGRIYHFPAYQWMDGYETLALREATGKT
TADDSLPVLLEHRKEEIRAKQDFYHWRVFLPGLPSYVHIPSYRPPVRRHRNPNRPEWNGY
IPGFPILINFKATKFLNLNLRYSFLKTASFFVRLGPMALAFKVRGLLDCKHSWKRLKDIR
KIFPGKKSVVSEYVAEHWAEDTFFGYQYLNGVNPGLIRRCTRIPDKFPVTDDMVAPFLGE
GTCLQAELEKGNIYLADYRIMEGIPTVELSGRKQHHCAPLCLLHFGPEGKMMPIAIQLSQ
TPGPDCPIFLPSDSEWDWLLAKTWVRYAEFYSHEAIAHLLETHLIAEAFCLALLRNLPMC
HPLYKLLIPHTRYTVQINSIGRAVLLNEGGLSAKGMSLGVEGFAGVMVRALSELTYDSLY
LPNDFVERGVQDLPGYYYRDDSLAVWNALEKYVTEIITYYYPSDAAVEGDPELQSWVQEI
FKECLLGRESSGFPRCLRTVPELIRYVTIVIYTCSAKHAAVNTGQMEFTAWMPNFPASMR
NPPIQTKGLTTLETFMDTLPDVKTTCITLLVLWTLSREPDDRRPLGHFPDIHFVEEAPRR
SIEAFRQRLNQISHDIRQRNKCLPIPYYYLDPVLIENSISI
NT seq
2106 nt
NT seq
+upstream
nt +downstream
nt
atggccacctacaaagtcagggtggccacaggcaccgacctcttgtcgggaacacgggac
tccatctcactgaccattgtggggacacaaggagagagccataagcagctgctgaaccac
tttgggagagactttgcaactggggcggtgggccagtacaccgtgcagtgccctcaggac
ctgggtgagctcatcatcatccgcctgcacaaagagcggtacgccttcttccccaaggac
ccttggtactgcaactatgtgcagatctgtgcccccaacggccgtatctaccacttcccc
gcctaccagtggatggatggctacgagaccctggcactccgggaggccacaggaaagaca
acagcagatgactcgctccccgtcctcctggagcacagaaaagaggagatcagagccaag
caggacttctaccactggcgagtctttcttcctggcctgcccagctatgtgcacattccc
agttaccgccctccggtgcggaggcatcgcaaccccaaccggcctgagtggaatggctat
attccgggattcccaattctcatcaactttaaggccaccaagttcctgaacttaaatctc
cgctactccttcctcaagacggcctccttcttcgtccgcctggggcccatggcactggct
ttcaaagtccgcggcctgttggactgcaaacattcgtggaagaggctgaaggacattagg
aaaattttccctggcaagaaatctgtcgtctccgagtacgtggccgagcactgggcagag
gacaccttctttgggtaccagtacctcaacggcgtcaaccccggcctgatccgccgctgc
acgcggatcccagacaagttccccgtcacagacgacatggtggctccgttcctgggcgag
ggaacgtgcttgcaagcggagctggagaaggggaacatttacctggccgactaccgcatc
atggagggcatccccaccgtggagctcagcggccggaagcagcaccactgcgcccccctc
tgcctgctgcactttggacccgagggcaagatgatgcccatcgccatccagctcagccag
acccctgggccagattgccccatcttcctgcccagtgattctgagtgggactggctgcta
gccaagacgtgggtacgctatgcggagttctacagccacgaggccatcgcccacctgctg
gagacacacctcattgctgaggccttctgcctggccttgctgaggaacctgcccatgtgc
caccccctctacaagctcctcatcccccatacccgatacaccgtccagatcaacagcatt
ggccgggccgttctcctcaatgagggggggctctctgccaagggcatgtccctgggcgtg
gaaggctttgctggggtgatggtacgggctctgtcggagctcacctatgacagcctctac
ctccccaatgactttgtggagcgtggggtccaggacctgcctggatattactaccgcgat
gacagcttggcggtgtggaatgcactggagaagtatgtgacggagatcatcacctattat
tacccgagtgacgcagccgtggagggtgatccggaattgcagtcttgggtgcaggaaata
tttaaagagtgcctcctggggcgggagagctcaggcttccctaggtgcttgcgaaccgtg
cctgagctgatccgatatgtcactatagtcatctacacctgctctgccaagcacgctgct
gtcaacacaggccagatggagttcaccgcctggatgcccaacttcccagcgtccatgcgg
aatccaccgattcagactaaggggctgaccactctggagaccttcatggacacgttgccg
gatgtgaagaccacgtgcatcacgctgctggtgctctggaccctcagccgagagcctgac
gacaggcggcccctgggacacttcccggacattcacttcgtggaggaggccccgcggagg
agcatagaggcgttccgccagcgcctgaaccagatctcacacgacatccgccagcgcaac
aagtgccttcccatcccctactactacctggacccggtgctgattgagaacagcatttct
atttag
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