Homo sapiens (human): 1776
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Entry
1776 CDS
T01001
Symbol
DNASE1L3, D3, DHP2, DNAS1L3, LSD, SLEB16
Name
(RefSeq) deoxyribonuclease 1L3
KO
K11995
deoxyribonuclease-1-like protein [EC:3.1.21.-]
Organism
hsa
Homo sapiens (human)
Network
nt06520
CGAS-STING signaling
Element
N01571
DNA degradation by extracellular/endolysosomal DNAse
Disease
H00080
Systemic lupus erythematosus
Brite
KEGG Orthology (KO) [BR:
hsa00001
]
09190 Not Included in Pathway or Brite
09191 Unclassified: metabolism
99980 Enzymes with EC numbers
1776 (DNASE1L3)
BRITE hierarchy
SSDB
Ortholog
Paralog
Gene cluster
GFIT
Motif
Pfam:
Exo_endo_phos
Motif
Other DBs
NCBI-GeneID:
1776
NCBI-ProteinID:
NP_004935
OMIM:
602244
HGNC:
2959
Ensembl:
ENSG00000163687
UniProt:
Q13609
Structure
PDB
PDBj
LinkDB
All DBs
Position
3:complement(58192257..58210972)
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AA seq
305 aa
AA seq
DB search
MSRELAPLLLLLLSIHSALAMRICSFNVRSFGESKQEDKNAMDVIVKVIKRCDIILVMEI
KDSNNRICPILMEKLNRNSRRGITYNYVISSRLGRNTYKEQYAFLYKEKLVSVKRSYHYH
DYQDGDADVFSREPFVVWFQSPHTAVKDFVIIPLHTTPETSVKEIDELVEVYTDVKHRWK
AENFIFMGDFNAGCSYVPKKAWKNIRLRTDPRFVWLIGDQEDTTVKKSTNCAYDRIVLRG
QEIVSSVVPKSNSVFDFQKAYKLTEEEALDVSDHFPVEFKLQSSRAFTNSKKSVTLRKKT
KSKRS
NT seq
918 nt
NT seq
+upstream
nt +downstream
nt
atgtcacgggagctggccccactgctgcttctcctcctctccatccacagcgccctggcc
atgaggatctgctccttcaacgtcaggtcctttggggaaagcaagcaggaagacaagaat
gccatggatgtcattgtgaaggtcatcaaacgctgtgacatcatactcgtgatggaaatc
aaggacagcaacaacaggatctgccccatactgatggagaagctgaacagaaattcaagg
agaggcataacgtacaactatgtgattagctctcggcttggaagaaacacatataaagaa
caatatgcctttctctacaaggaaaagctggtgtctgtgaagaggagttatcactaccat
gactatcaggatggagacgcagatgtgttttccagggagccctttgtggtctggttccaa
tctccccacactgctgtcaaagacttcgtgattatccccctgcacaccaccccagagaca
tccgttaaggagatcgatgagttggttgaggtctacacggacgtgaaacaccgctggaag
gcggagaatttcattttcatgggtgacttcaatgccggctgcagctacgtccccaagaag
gcctggaagaacatccgcttgaggactgaccccaggtttgtttggctgatcggggaccaa
gaggacaccacggtgaagaagagcaccaactgtgcatatgacaggattgtgcttagagga
caagaaatcgtcagttctgttgttcccaagtcaaacagtgtttttgacttccagaaagct
tacaagctgactgaagaggaggccctggatgtcagcgaccactttccagttgaatttaaa
ctacagtcttcaagggccttcaccaacagcaaaaaatctgtcactctaaggaagaaaaca
aagagcaaacgctcctag
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