KEGG   Homo sapiens (human): 3020
Entry
3020              CDS       T01001                                 
Symbol
H3-3A, BRYLIB1, H3-3B, H3.3A, H3F3, H3F3A
Name
(RefSeq) H3.3 histone A
  KO
K11253  histone H3
Organism
hsa  Homo sapiens (human)
Pathway
hsa04613  Neutrophil extracellular trap formation
hsa05034  Alcoholism
hsa05131  Shigellosis
hsa05202  Transcriptional misregulation in cancer
hsa05322  Systemic lupus erythematosus
Network
nt06240  Transcription (cancer)
nt06512  Chromosome cohesion and segregation
nt06523  Epigenetic regulation by Polycomb complexes
  Element
N00125  IGH-MMSET fusion to transcriptional activation
N01577  Gene silencing by methylation of H3K27 and ubiquitination of H2AK119
N01701  Transcriptional activation by acetylation of H3K27
N01813  Enhancement of NIPBL loading
Disease
H01470  Giant cell tumor of bone
H02617  Bryant-Li-Bhoj neurodevelopmental syndrome
Brite
KEGG Orthology (KO) [BR:hsa00001]
 09150 Organismal Systems
  09151 Immune system
   04613 Neutrophil extracellular trap formation
    3020 (H3-3A)
 09160 Human Diseases
  09161 Cancer: overview
   05202 Transcriptional misregulation in cancer
    3020 (H3-3A)
  09171 Infectious disease: bacterial
   05131 Shigellosis
    3020 (H3-3A)
  09163 Immune disease
   05322 Systemic lupus erythematosus
    3020 (H3-3A)
  09165 Substance dependence
   05034 Alcoholism
    3020 (H3-3A)
 09180 Brite Hierarchies
  09182 Protein families: genetic information processing
   03036 Chromosome and associated proteins [BR:hsa03036]
    3020 (H3-3A)
  09183 Protein families: signaling and cellular processes
   04147 Exosome [BR:hsa04147]
    3020 (H3-3A)
Chromosome and associated proteins [BR:hsa03036]
 Eukaryotic type
  Nucleosome assembly factors
   Histones
    3020 (H3-3A)
Exosome [BR:hsa04147]
 Exosomal proteins
  Exosomal proteins of haemopoietic cells  (B-cell, T-cell, DC-cell, reticulocyte, and mast cell)
   3020 (H3-3A)
SSDB
Motif
Pfam: Histone CENP-T_C PAF CENP-S CBFD_NFYB_HMF TFIID-31kDa
Other DBs
NCBI-GeneID: 3020
NCBI-ProteinID: NP_002098
OMIM: 601128
HGNC: 4764
Ensembl: ENSG00000163041
UniProt: P84243 B2R4P9
Structure
LinkDB
Position
1:226061831..226072019
AA seq 136 aa
MARTKQTARKSTGGKAPRKQLATKAARKSAPSTGGVKKPHRYRPGTVALREIRRYQKSTE
LLIRKLPFQRLVREIAQDFKTDLRFQSAAIGALQEASEAYLVGLFEDTNLCAIHAKRVTI
MPKDIQLARRIRGERA
NT seq 411 nt   +upstreamnt  +downstreamnt
atggctcgtacaaagcagactgcccgcaaatcgaccggtggtaaagcacccaggaagcaa
ctggctacaaaagccgctcgcaagagtgcgccctctactggaggggtgaagaaacctcat
cgttacaggcctggtactgtggcgctccgtgaaattagacgttatcagaagtccactgaa
cttctgattcgcaaacttcccttccagcgtctggtgcgagaaattgctcaggactttaaa
acagatctgcgcttccagagcgcagctatcggtgctttgcaggaggcaagtgaggcctat
ctggttggcctttttgaagacaccaacctgtgtgctatccatgccaaacgtgtaacaatt
atgccaaaagacatccagctagcacgccgcatacgtggagaacgtgcttaa

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