| Entry |
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| Symbol |
HCN1, BCNG-1, BCNG1, DEE24, EIEE24, GEFSP10, HAC-2
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| Name |
(RefSeq) hyperpolarization activated cyclic nucleotide gated potassium channel 1
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| KO |
| K04954 | hyperpolarization activated cyclic nucleotide-gated potassium channel 1 |
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| Organism |
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| Pathway |
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| Network |
nt06544 Neuroactive ligand signaling |
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| Element |
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| Disease |
| H00606 | Early infantile epileptic encephalopathy |
| H02564 | Generalized epilepsy with febrile seizures plus |
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| Drug target |
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| Brite |
KEGG Orthology (KO) [BR:hsa00001]
09150 Organismal Systems
09152 Endocrine system
04929 GnRH secretion
348980 (HCN1)
09180 Brite Hierarchies
09183 Protein families: signaling and cellular processes
04040 Ion channels [BR:hsa04040]
348980 (HCN1)
Ion channels [BR:hsa04040]
Voltage-gated cation channels
Cyclic nucleotide-gated channel (HCN)
348980 (HCN1)
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| SSDB |
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| Motif |
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| Other DBs |
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| Structure |
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| LinkDB |
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| Position |
5:complement(45254948..45696380)
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| AA seq |
890 aa
MEGGGKPNSSSNSRDDGNSVFPAKASATGAGPAAAEKRLGTPPGGGGAGAKEHGNSVCFK
VDGGGGGGGGGGGGEEPAGGFEDAEGPRRQYGFMQRQFTSMLQPGVNKFSLRMFGSQKAV
EKEQERVKTAGFWIIHPYSDFRFYWDLIMLIMMVGNLVIIPVGITFFTEQTTTPWIIFNV
ASDTVFLLDLIMNFRTGTVNEDSSEIILDPKVIKMNYLKSWFVVDFISSIPVDYIFLIVE
KGMDSEVYKTARALRIVRFTKILSLLRLLRLSRLIRYIHQWEEIFHMTYDLASAVVRIFN
LIGMMLLLCHWDGCLQFLVPLLQDFPPDCWVSLNEMVNDSWGKQYSYALFKAMSHMLCIG
YGAQAPVSMSDLWITMLSMIVGATCYAMFVGHATALIQSLDSSRRQYQEKYKQVEQYMSF
HKLPADMRQKIHDYYEHRYQGKIFDEENILNELNDPLREEIVNFNCRKLVATMPLFANAD
PNFVTAMLSKLRFEVFQPGDYIIREGAVGKKMYFIQHGVAGVITKSSKEMKLTDGSYFGE
ICLLTKGRRTASVRADTYCRLYSLSVDNFNEVLEEYPMMRRAFETVAIDRLDRIGKKNSI
LLQKFQKDLNTGVFNNQENEILKQIVKHDREMVQAIAPINYPQMTTLNSTSSTTTPTSRM
RTQSPPVYTATSLSHSNLHSPSPSTQTPQPSAILSPCSYTTAVCSPPVQSPLAARTFHYA
SPTASQLSLMQQQPQQQVQQSQPPQTQPQQPSPQPQTPGSSTPKNEVHKSTQALHNTNLT
REVRPLSASQPSLPHEVSTLISRPHPTVGESLASIPQPVTAVPGTGLQAGGRSTVPQRVT
LFRQMSSGAIPPNRGVPPAPPPPAAALPRESSSVLNTDPDAEKPRFASNL |
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| NT seq |
2673 nt +upstreamnt +downstreamnt
atggaaggaggcggcaagcccaactcttcgtctaacagccgggacgatggcaacagcgtc
ttccccgccaaggcgtccgcgacgggcgcggggccggccgcggccgagaagcgcctgggc
accccgccggggggcggcggggccggcgcgaaggagcacggcaactccgtgtgcttcaag
gtggacggcggtggcggcggtggcggcggcggcggcggcggcgaggagccggcggggggc
ttcgaagacgccgaggggccccggcggcagtacggcttcatgcagaggcagttcacctcc
atgctgcagcccggggtcaacaaattctccctccgcatgtttgggagccagaaggcggtg
gaaaaggagcaggaaagggttaaaactgcaggcttctggattatccacccttacagtgat
ttcaggttttactgggatttaataatgcttataatgatggttggaaatctagtcatcata
ccagttggaatcacattctttacagagcaaacaacaacaccatggattattttcaatgtg
gcatcagatacagttttcctattggacctgatcatgaattttaggactgggactgtcaat
gaagacagttctgaaatcatcctggaccccaaagtgatcaagatgaattatttaaaaagc
tggtttgtggttgacttcatctcatccatcccagtggattatatctttcttattgtagaa
aaaggaatggattctgaagtttacaagacagccagggcacttcgcattgtgaggtttaca
aaaattctcagtctcttgcgtttattacgactttcaaggttaattagatacatacatcaa
tgggaagagatattccacatgacatatgatctcgccagtgcagtggtgagaatttttaat
ctcatcggcatgatgctgctcctgtgccactgggatggttgtcttcagttcttagtacca
ctactgcaggacttcccaccagattgctgggtgtctttaaatgaaatggttaatgattct
tggggaaagcagtattcatacgcactcttcaaagctatgagtcacatgctgtgcattggg
tatggagcccaagccccagtcagcatgtctgacctctggattaccatgctgagcatgatc
gtcggggccacctgctatgccatgtttgtcggccatgccaccgctttaatccagtctctg
gattcttcgaggcggcagtatcaagagaagtataagcaagtggaacaatacatgtcattc
cataagttaccagctgatatgcgtcagaagatacatgattactatgaacacagataccaa
ggcaaaatctttgatgaggaaaatattctcaatgaactcaatgatcctctgagagaggag
atagtcaacttcaactgtcggaaactggtggctacaatgcctttatttgctaatgcggat
cctaattttgtgactgccatgctgagcaagttgagatttgaggtgtttcaacctggagat
tatatcatacgagaaggagccgtgggtaaaaaaatgtatttcattcaacacggtgttgct
ggtgtcattacaaaatccagtaaagaaatgaagctgacagatggctcttactttggagag
atttgcctgctgaccaaaggacgtcgtactgccagtgttcgagctgatacatattgtcgt
ctttactcactttccgtggacaatttcaacgaggtcctggaggaatatccaatgatgagg
agagcctttgagacagttgccattgaccgactagatcgaataggaaagaaaaattcaatt
cttctgcaaaagttccagaaggatctgaacactggtgttttcaacaatcaggagaacgaa
atcctcaagcagattgtgaaacatgacagggagatggtgcaggcaatcgctcccatcaat
tatcctcaaatgacaaccctgaattccacatcgtctactacgaccccgacctcccgcatg
aggacacaatctccaccggtgtacacagcgaccagcctgtctcacagcaacctgcactcc
cccagtcccagcacacagaccccccagccatcagccatcctgtcaccctgctcctacacc
accgcggtctgcagccctcctgtacagagccctctggccgctcgaactttccactatgcc
tcccccaccgcctcccagctgtcactcatgcaacagcagccgcagcagcaggtacagcag
tcccagccgccgcagactcagccacagcagccgtccccgcagccacagacacctggcagc
tccacgccgaaaaatgaagtgcacaagagcacgcaggcgcttcacaacaccaacctgacc
cgggaagtcaggccactctccgcctcgcagccctcgctgccccatgaggtgtccactctg
atttccagacctcatcccactgtgggcgagtccctggcctccatccctcaacccgtgacg
gcggtccccggaacgggccttcaggcagggggcaggagcactgtcccgcagcgcgtcacc
ctcttccgacagatgtcgtcgggagccatccccccgaaccgaggagtccctccagcaccc
cctccaccagcagctgctcttccaagagaatcttcctcagtcttaaacacagacccagac
gcagaaaagccacgatttgcttcaaatttatga |
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