Homo sapiens (human): 8930
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Entry
8930 CDS
T01001
Symbol
MBD4, MED1, TPDS2, UVM1
Name
(RefSeq) methyl-CpG binding domain 4, DNA glycosylase
KO
K10801
methyl-CpG-binding domain protein 4 [EC:3.2.2.-]
Organism
hsa
Homo sapiens (human)
Pathway
hsa03410
Base excision repair
Network
nt06504
Base excision repair
Element
N01433
Base excision and strand cleavage by monofunctional glycosylase
Disease
H02624
Tumor predisposition syndrome
Brite
KEGG Orthology (KO) [BR:
hsa00001
]
09120 Genetic Information Processing
09124 Replication and repair
03410 Base excision repair
8930 (MBD4)
09180 Brite Hierarchies
09182 Protein families: genetic information processing
03036 Chromosome and associated proteins [BR:
hsa03036
]
8930 (MBD4)
03400 DNA repair and recombination proteins [BR:
hsa03400
]
8930 (MBD4)
Chromosome and associated proteins [BR:
hsa03036
]
Eukaryotic type
Heterochromatin formation proteins
MBPs (metylated DNA binding proteins)
8930 (MBD4)
DNA repair and recombination proteins [BR:
hsa03400
]
Eukaryotic type
SSBR (single strand breaks repair)
BER (base exicision repair)
DNA glycosylases
8930 (MBD4)
BRITE hierarchy
SSDB
Ortholog
Paralog
Gene cluster
GFIT
Motif
Pfam:
MBD
HhH-GPD
Motif
Other DBs
NCBI-GeneID:
8930
NCBI-ProteinID:
NP_003916
OMIM:
603574
HGNC:
6919
Ensembl:
ENSG00000129071
UniProt:
O95243
Structure
PDB
PDBj
LinkDB
All DBs
Position
3:complement(129430947..129439948)
Genome browser
AA seq
580 aa
AA seq
DB search
MGTTGLESLSLGDRGAAPTVTSSERLVPDPPNDLRKEDVAMELERVGEDEEQMMIKRSSE
CNPLLQEPIASAQFGATAGTECRKSVPCGWERVVKQRLFGKTAGRFDVYFISPQGLKFRS
KSSLANYLHKNGETSLKPEDFDFTVLSKRGIKSRYKDCSMAALTSHLQNQSNNSNWNLRT
RSKCKKDVFMPPSSSSELQESRGLSNFTSTHLLLKEDEGVDDVNFRKVRKPKGKVTILKG
IPIKKTKKGCRKSCSGFVQSDSKRESVCNKADAESEPVAQKSQLDRTVCISDAGACGETL
SVTSEENSLVKKKERSLSSGSNFCSEQKTSGIINKFCSAKDSEHNEKYEDTFLESEEIGT
KVEVVERKEHLHTDILKRGSEMDNNCSPTRKDFTGEKIFQEDTIPRTQIERRKTSLYFSS
KYNKEALSPPRRKAFKKWTPPRSPFNLVQETLFHDPWKLLIATIFLNRTSGKMAIPVLWK
FLEKYPSAEVARTADWRDVSELLKPLGLYDLRAKTIVKFSDEYLTKQWKYPIELHGIGKY
GNDSYRIFCVNEWKQVHPEDHKLNKYHDWLWENHEKLSLS
NT seq
1743 nt
NT seq
+upstream
nt +downstream
nt
atgggcacgactgggctggagagtctgagtctgggggaccgcggagctgcccccaccgtc
acctctagtgagcgcctagtcccagacccgccgaatgacctccgcaaagaagatgttgct
atggaattggaaagagtgggagaagatgaggaacaaatgatgataaaaagaagcagtgaa
tgtaatcccttgctacaagaacccatcgcttctgctcagtttggtgctactgcaggaaca
gaatgccgtaagtctgtcccatgtggatgggaaagagttgtgaagcaaaggttatttggg
aagacagcaggaagatttgatgtgtactttatcagcccacaaggactgaagttcagatcc
aaaagttcacttgctaattatcttcacaaaaatggagagacttctcttaagccagaagat
tttgattttactgtactttctaaaaggggtatcaagtcaagatataaagactgcagcatg
gcagccctgacatcccatctacaaaaccaaagtaacaattcaaactggaacctcaggacc
cgaagcaagtgcaaaaaggatgtgtttatgccgccaagtagtagttcagagttgcaggag
agcagaggactctctaactttacttccactcatttgcttttgaaagaagatgagggtgtt
gatgatgttaacttcagaaaggttagaaagcccaaaggaaaggtgactattttgaaagga
atcccaattaagaaaactaaaaaaggatgtaggaagagctgttcaggttttgttcaaagt
gatagcaaaagagaatctgtgtgtaataaagcagatgctgaaagtgaacctgttgcacaa
aaaagtcagcttgatagaactgtctgcatttctgatgctggagcatgtggtgagaccctc
agtgtgaccagtgaagaaaacagccttgtaaaaaaaaaagaaagatcattgagttcagga
tcaaatttttgttctgaacaaaaaacttctggcatcataaacaaattttgttcagccaaa
gactcagaacacaacgagaagtatgaggatacctttttagaatctgaagaaatcggaaca
aaagtagaagttgtggaaaggaaagaacatttgcatactgacattttaaaacgtggctct
gaaatggacaacaactgctcaccaaccaggaaagacttcactggtgagaaaatatttcaa
gaagataccatcccacgaacacagatagaaagaaggaaaacaagcctgtatttttccagc
aaatataacaaagaagctcttagccccccacgacgtaaagcctttaagaaatggacacct
cctcggtcaccttttaatctcgttcaagaaacactttttcatgatccatggaagcttctc
atcgctactatatttctcaatcggacctcaggcaaaatggcaatacctgtgctttggaag
tttctggagaagtatccttcagctgaggtagcaagaaccgcagactggagagatgtgtca
gaacttcttaaacctcttggtctctacgatcttcgggcaaaaaccattgtcaagttctca
gatgaatacctgacaaagcagtggaagtatccaattgagcttcatgggattggtaaatat
ggcaacgactcttaccgaattttttgtgtcaatgagtggaagcaggtgcaccctgaagac
cacaaattaaataaatatcatgactggctttgggaaaatcatgaaaaattaagtctatct
taa
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integrated database retrieval system
