KEGG   VARIANT: 4609v1
Entry
4609v1                      Variant                                
Name
MYC amplification
Gene
MYC  MYC proto-oncogene, bHLH transcription factor [KO:K04377]
Organism
hsa_var Human gene variants (Homo sapiens)
Variation
Network
nt06230  Cell cycle
nt06267  Small cell lung cancer
  Element
N00088  Amplified MYC to p15-cell cycle G1/S
N00089  Amplified MYC to cell cycle G1/S
N00092  Amplified MYC to p27-cell cycle G1/S
Disease
H00013  Small cell lung cancer
Reference
PMID:9508209
  Authors
Salgia R, Skarin AT
  Title
Molecular abnormalities in lung cancer.
  Journal
J Clin Oncol 16:1207-17 (1998)
DOI:10.1200/JCO.1998.16.3.1207
Reference
  Authors
Osada H, Takahashi T.
  Title
Genetic alterations of multiple tumor suppressors and oncogenes in the carcinogenesis and progression of lung cancer.
  Journal
Oncogene 21:7421-34 (2002)
DOI:10.1038/sj.onc.1205802
Reference
  Authors
Meuwissen R, Berns A.
  Title
Mouse models for human lung cancer.
  Journal
Genes Dev 19:643-64 (2005)
DOI:10.1101/gad.1284505
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