KEGG   Hibiscus syriacus (Rose-of-Sharon): 120175428
Entry
120175428         CDS       T09559                                 
Name
(RefSeq) bifunctional dihydrofolate reductase-thymidylate synthase-like isoform X1
  KO
K13998  dihydrofolate reductase / thymidylate synthase [EC:1.5.1.3 2.1.1.45]
Organism
hsyr  Hibiscus syriacus (Rose-of-Sharon)
Pathway
hsyr00240  Pyrimidine metabolism
hsyr00670  One carbon pool by folate
hsyr00790  Folate biosynthesis
hsyr01100  Metabolic pathways
hsyr01232  Nucleotide metabolism
hsyr01240  Biosynthesis of cofactors
Module
hsyr_M00126  Tetrahydrofolate biosynthesis, GTP => THF
hsyr_M00938  Pyrimidine deoxyribonucleotide biosynthesis, UDP => dTTP
Brite
KEGG Orthology (KO) [BR:hsyr00001]
 09100 Metabolism
  09104 Nucleotide metabolism
   00240 Pyrimidine metabolism
    120175428
  09108 Metabolism of cofactors and vitamins
   00790 Folate biosynthesis
    120175428
   00670 One carbon pool by folate
    120175428
Enzymes [BR:hsyr01000]
 1. Oxidoreductases
  1.5  Acting on the CH-NH group of donors
   1.5.1  With NAD+ or NADP+ as acceptor
    1.5.1.3  dihydrofolate reductase
     120175428
 2. Transferases
  2.1  Transferring one-carbon groups
   2.1.1  Methyltransferases
    2.1.1.45  thymidylate synthase
     120175428
SSDB
Motif
Pfam: Thymidylat_synt DHFR_1
Other DBs
NCBI-GeneID: 120175428
NCBI-ProteinID: XP_039037978
LinkDB
Position
Unknown
AA seq 560 aa
MFPIQIGRFYLKQIWKTSPLSVCFVFSSNMSANTMTSKPNGNGNGNVDVDFLPDPRRTYQ
VVMAATKDWGIGKNGKLPWKIPTDIKFFNDVTRTTLDPGKRNAVIMGRKTWESITPEYRP
LSSRLNVVLTRSGSFDIATAENVVICGSLASALELLAASPYCLSIEKVFVIGGGQILRDS
LNAAGCDAIHITEIETSIECDTFMPAIDFSVFQPWYSSFPLVENNIRYSFNTYVRVRTSA
VEHINQDCNQILDIDSSKFEVHNFSFLPKMIFEKHEEYLYLNMIQDIISDGNMKDDRTGT
GTLSKFGCQMRFNLRKTFPLLTTKKVFWRGVVEELLWFISGSTNAKVLQEKDIHIWDGNA
SREFLDSIGLTGREEGDLGPVYGFQWRHFGARYTNMHADYTGQGFDQLSDVIDKIKNNPN
DRRIILSAWNPSDLKLMALPPCHMFAQFYVANGELSCQLYQRSCDMGLGVPFNIASYALL
TCMIAHVCDLVPGDFIHVLGDTHVYTTHVRPLQEQLQKLPKPFPILKINPVKKNIDSLVA
SDFKLIGYDPHKKIEMKMAV
NT seq 1683 nt   +upstreamnt  +downstreamnt
atgtttccgattcagatcggtcggttttatctaaaacaaatttggaagacttccccattg
agtgtctgttttgtttttagttcaaatatgtctgccaacaccatgacgagcaaacctaat
ggaaatggtaatggcaatgttgatgtcgatttcttacctgatccacgacgaacttaccaa
gtcgttatggccgcgactaaagattggggtatcggtaagaatgggaagttgccttggaaa
atacctaccgatataaaattcttcaatgatgtcactcgtactactttagaccctgggaaa
aggaatgcagtcataatgggcagaaaaacatgggaaagtattacccctgaatatcgacct
ctttcgagtcgtctcaatgttgttctgactcgttccggaagttttgatattgcaaccgct
gagaatgttgttatatgtggaagcctggcgtccgctttggaattattagctgcttctcct
tattgtctctcgatcgagaaagtctttgtaattggcggtggccaaatattgagggactcc
ctcaatgcagctggatgtgatgctattcacattacagaaattgagacgagcatcgaatgt
gatacttttatgcctgccattgatttctctgtattccagccttggtactcatcatttcct
ctggtagagaacaacatacggtatagtttcaatacatatgttcgtgtgagaacctctgca
gttgaacacattaaccaggactgcaatcagatccttgatatagattcctccaagtttgag
gtacataatttctctttcctgcccaagatgatttttgagaaacacgaggagtacttgtac
ctcaatatgattcaagacatcatctccgatggtaatatgaaggatgacaggaccgggact
ggtacattatcaaaatttggttgccagatgcggttcaacttgcgaaaaacttttccgctt
ctgacaactaagaaagtattttggcgaggtgttgttgaagagttgctatggttcatcagt
ggctcaactaatgccaaggtccttcaagaaaaggacattcatatatgggatgggaatgca
tccagggagtttcttgacagtattgggttgactggcagggaggagggtgacttgggacct
gtgtatgggttccagtggagacattttggtgctaggtataccaacatgcatgccgattac
actggacaaggatttgatcagttgtcggatgttattgacaagattaagaataatccaaat
gatagaaggattatactctcagcctggaatccttcggatctcaaactgatggcacttcct
ccttgccacatgtttgctcagttctatgtagcaaatggggagttatcatgtcaattgtat
cagcgctcatgtgacatgggcttgggtgtgccatttaacattgcatcttatgctctcctc
acgtgcatgattgctcacgtttgtgatcttgttccgggtgatttcatccacgttcttggc
gatactcatgtttataccactcatgtcaggcccctgcaggagcagcttcagaaattgcca
aagccttttccgattttgaagatcaatcccgtgaaaaagaatatcgattccttagtggct
tccgatttcaaactcataggttatgatcctcacaagaaaatagagatgaaaatggctgta
tag

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