KEGG   PATHWAY: iti00531
Entry
iti00531                    Pathway                                
Name
Glycosaminoglycan degradation - Ictidomys tridecemlineatus (thirteen-lined ground squirrel)
Class
Metabolism; Glycan biosynthesis and metabolism
Pathway map
iti00531  Glycosaminoglycan degradation
iti00531

Module
iti_M00076  Dermatan sulfate degradation [PATH:iti00531]
iti_M00077  Chondroitin sulfate degradation [PATH:iti00531]
iti_M00078  Heparan sulfate degradation [PATH:iti00531]
iti_M00079  Keratan sulfate degradation [PATH:iti00531]
Other DBs
GO: 0006027
Organism
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) [GN:iti]
Gene
101954755  Sgsh; N-sulphoglucosamine sulphohydrolase [KO:K01565] [EC:3.10.1.1]
101956007  Galns; N-acetylgalactosamine-6-sulfatase [KO:K01132] [EC:3.1.6.4]
101960045  Hexa; beta-hexosaminidase subunit alpha [KO:K12373] [EC:3.2.1.52]
101960876  Hexb; LOW QUALITY PROTEIN: beta-hexosaminidase subunit beta [KO:K12373] [EC:3.2.1.52]
101961359  Hgsnat; heparan-alpha-glucosaminide N-acetyltransferase isoform X1 [KO:K10532] [EC:2.3.1.78]
101961467  Hpse2; inactive heparanase-2 [KO:K07965] [EC:3.2.1.-]
101961768  Glb1; beta-galactosidase isoform X2 [KO:K12309] [EC:3.2.1.23]
101961995  Ids; iduronate 2-sulfatase [KO:K01136] [EC:3.1.6.13]
101967452  Naglu; alpha-N-acetylglucosaminidase [KO:K01205] [EC:3.2.1.50]
101968870  Hpse; heparanase [KO:K07964] [EC:3.2.1.166]
101970770  Hyal4; hyaluronidase-4 [KO:K01197] [EC:3.2.1.35]
101971329  Arsb; arylsulfatase B [KO:K01135] [EC:3.1.6.12]
101972107  Gusb; beta-glucuronidase [KO:K01195] [EC:3.2.1.31]
101974489  Gns; N-acetylglucosamine-6-sulfatase [KO:K01137] [EC:3.1.6.14]
101975318  Hyal3; hyaluronidase-3 isoform X1 [KO:K01197] [EC:3.2.1.35]
101975781  Hyal1; hyaluronidase-1 isoform X2 [KO:K01197] [EC:3.2.1.35]
101976055  Hyal2; hyaluronidase-2 [KO:K01197] [EC:3.2.1.35]
101976566  Spam1; hyaluronidase PH-20 [KO:K01197] [EC:3.2.1.35]
101976844  [KO:K01197] [EC:3.2.1.35]
101978346  Idua; alpha-L-iduronidase isoform X4 [KO:K01217] [EC:3.2.1.76]
Compound
C00426  Dermatan sulfate
C00573  Keratan sulfate
C00634  Chondroitin 4-sulfate
C00925  Heparan sulfate
G00526  
G00711  
G00872  DWA-2
G01391  
G01945  
G01977  
G02632  
G09660  
G10008  
G10505  Hyaluronic acid
G12336  
G13034  
G13035  
G13036  
G13037  
G13038  
G13039  
G13040  
G13041  
G13042  
G13043  
G13073  
G13074  
Reference
PMID:27570
  Authors
Greiling H, Stuhlsatz HW, Cantz M, Gehler J
  Title
Increased urinary excretion of keratan sulfate in fucosidosis.
  Journal
J Clin Chem Clin Biochem 16:329-34 (1978)
DOI:10.1515/cclm.1978.16.6.329
Reference
PMID:3161730
  Authors
Fuchs W, Beck M, Kresse H
  Title
Intralysosomal formation and metabolic fate of N-acetylglucosamine 6-sulfate from keratan sulfate.
  Journal
Eur J Biochem 151:551-6 (1985)
DOI:10.1111/j.1432-1033.1985.tb09138.x
Related
pathway
iti00532  Glycosaminoglycan biosynthesis - chondroitin sulfate / dermatan sulfate
iti00533  Glycosaminoglycan biosynthesis - keratan sulfate
iti00534  Glycosaminoglycan biosynthesis - heparan sulfate / heparin
KO pathway
ko00531   

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