KEGG   Ictidomys tridecemlineatus (thirteen-lined ground squirrel): 101977414
Entry
101977414         CDS       T10664                                 
Name
(RefSeq) steroid 21-hydroxylase
  KO
K00513  steroid 21-monooxygenase [EC:1.14.14.16]
Organism
iti  Ictidomys tridecemlineatus (thirteen-lined ground squirrel)
Pathway
iti00140  Steroid hormone biosynthesis
iti01100  Metabolic pathways
iti04925  Aldosterone synthesis and secretion
iti04927  Cortisol synthesis and secretion
iti04934  Cushing syndrome
Module
iti_M00109  C21-Steroid hormone biosynthesis, progesterone => cortisol/cortisone
Brite
KEGG Orthology (KO) [BR:iti00001]
 09100 Metabolism
  09103 Lipid metabolism
   00140 Steroid hormone biosynthesis
    101977414
 09150 Organismal Systems
  09152 Endocrine system
   04925 Aldosterone synthesis and secretion
    101977414
   04927 Cortisol synthesis and secretion
    101977414
 09160 Human Diseases
  09167 Endocrine and metabolic disease
   04934 Cushing syndrome
    101977414
 09180 Brite Hierarchies
  09181 Protein families: metabolism
   00199 Cytochrome P450 [BR:iti00199]
    101977414
Enzymes [BR:iti01000]
 1. Oxidoreductases
  1.14  Acting on paired donors, with incorporation or reduction of molecular oxygen
   1.14.14  With reduced flavin or flavoprotein as one donor, and incorporation of one atom of oxygen into the other donor
    1.14.14.16  steroid 21-monooxygenase
     101977414
Cytochrome P450 [BR:iti00199]
 Cytochrome P450, animal type
  CYP21 family
   101977414
SSDB
Motif
Pfam: p450
Other DBs
NCBI-GeneID: 101977414
NCBI-ProteinID: XP_040138349
LinkDB
Position
Unknown
AA seq 494 aa
MLFLGLLLLLTLLAGSRLLWGQRKLRGFHLPPRAPGFLHFLQPNLPIYLLSLTRKLGPIY
RLRLGLQDVVVLNSTRAIEEAMVRKWADFAGRPRVPSYKLVSHNHPDLSLGDYSLLWKAH
KKLARSALLLGVRESMESLLKQLTQEFCEHLRVQASAPLAIQKEFSFFACNIICCLTFGK
KVKDDILGHAIYNCVQDVLKAWNHWSVQILDLVPFLKFFPNPGVWKLKKIMEKRDKIVEQ
QLRQHKESLVTGQWRDMIDYMLQELGRPREDSGSGQLLEGHVHMAVVDLFIGGTETTATT
LSWAVAFLLHYPEVQHRLQKELDLQLGPGTSSSQVLYKDRMRLPLLNATISEVLRLRPVV
PLALPHRTIRPSSILGYDIPEDTVIIPNLQGANLDEMVWERPQEFWPDRFLKPGKNPKVT
SFGCGARVCLGEPLARVELFMVLANLLQAFTLLPEGALPSLQPQPYSGVNLLMQPFQVRL
QPRDLGAPGHDQCQ
NT seq 1485 nt   +upstreamnt  +downstreamnt
atgctgtttcttgggctgttgttgctgctgacactattggctggcagccgcctgctgtgg
ggccagaggaaactcaggggcttccacctccctcctcgtgccccaggcttcctgcacttt
ctgcaacccaacctccccatctatctgctcagcctcactcggaaacttgggcccatctac
aggctccgcttggggcttcaggatgtcgtggtgctgaactccaccagggccatcgaggaa
gccatggtcagaaagtgggcggacttcgctggcagaccccgggtaccatcctacaagctg
gtgtctcacaaccatccagacctgtcactaggggactactccctgctctggaaggcccat
aagaaacttgcccgctcagccctgctactgggtgtccgtgaatccatggagtccctgctg
aagcagctgactcaggagttctgtgagcacctcagagtccaggccagtgcccccctggcc
atccagaaggaattttctttctttgcctgtaacatcatctgctgcctcacctttggaaaa
aaggtaaaggatgacatcctgggacatgccatttataactgtgttcaggatgtcttgaaa
gcttggaaccactggtccgtccaaattttggacttggttcctttcctcaagttcttcccc
aacccaggggtctggaagctgaagaagatcatggaaaaaagggacaaaattgtagagcag
cagctgaggcagcacaaggagagtttggtgacaggccagtggagagacatgatagactac
atgctccaagagctggggcggccgagagaggacagtggttctggacagctccttgaaggg
cacgtgcacatggccgtggtggaccttttcatcggtggcactgagaccacagcgaccacc
ctctcctgggctgtggctttcttgcttcactaccctgaggttcagcatcgactgcagaag
gagctggatctccaactggggcccgggacttcaagctcccaggtcctatataaggaccga
atgcgactgcccttgctcaatgccaccatctcagaggtgttacgccttcggcctgtggtg
cccttggccttaccccaccgcaccatccggcccagcagcatccttggctacgacatccct
gaggatacagtcatcatccctaacctccaaggtgccaaccttgacgagatggtctgggag
cggccacaggagttctggcctgaccgattcctgaagcctggcaagaaccccaaagtgaca
tcctttggctgtggggcacgcgtgtgcctaggagaaccactggcgcgtgtggaactcttc
atggtgctggccaacctgctccaggccttcacgctgctgcctgagggtgccctgccctct
ctgcagccccagccctacagtggtgtgaaccttctgatgcagcctttccaggtgcggctg
cagccccgggacctgggggccccagggcatgaccagtgccagtga

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