Entry
Name
Flavone and flavonol biosynthesis
Description
Flavones and flavonols (3-hydroxyflavones) are common flavonoids in the plant kingdom. They are synthesized as part of the flavonoid modification pathways in aglycone and glucoside forms.
Class
Metabolism; Biosynthesis of other secondary metabolites
BRITE hierarchy
Pathway map
ko00944 Flavone and flavonol biosynthesis
Ortholog table
Orthology
K13080 flavanone 7-O-glucoside 2''-O-beta-L-rhamnosyltransferase [EC:2.4.1.236 ]
K15787 flavonol-3-O-rhamnosyltransferase [EC:2.4.1.-]
K22771 flavonol-3-O-L-rhamnoside-7-O-glucosyltransferase [EC:2.4.1.-]
K22794 flavonol-3-O-glucoside/galactoside glucosyltransferase [EC:2.4.1.239 2.4.1.-]
Compound
C01155 Quercetin 3,3'-bissulfate
C01156 Quercetin 3,4'-bissulfate
C01265 3,7-Di-O-methylquercetin
C03515 Luteolin 7-O-glucuronide
C03897 Quercetin 3,3',7-trissulfate
C03898 Quercetin 3,4',7-trissulfate
C03951 Luteolin 7-O-beta-D-glucoside
C04024 Vitexin 2''-O-beta-D-glucoside
C04199 Isovitexin 2''-O-beta-D-glucoside
C04444 3,7,4'-Tri-O-methylquercetin
C04608 Apigenin 7-O-beta-D-glucoside
C04858 Apigenin 7-O-[beta-D-apiosyl-(1->2)-beta-D-glucoside]
C04900 Luteolin 7-O-[beta-D-glucuronosyl-(1->2)-beta-D-glucuronide]-4'-O-beta-D-glucuronide
C10175 Quercetin 3-(2G-xylosylrutinoside)
C12249 Kaempferol 3-O-glucoside
C12626 Kaempferol-3-O-galactoside
C12627 Apigenin 7-O-neohesperidoside
C12628 Vitexin 2''-O-beta-L-rhamnoside
C12629 Isoswertisin 2''-rhamnoside
C12632 Luteolin 7-O-[beta-D-glucuronosyl-(1->2)-beta-D-glucuronide]
C12634 Kaempferol 3-O-beta-D-glucosyl-(1->2)-beta-D-glucoside
C12635 Kaempferol 3-sophorotrioside
C12636 Kaempferol 3-O-[6-(4-coumaroyl)-beta-D-glucosyl-(1->2)-beta-D-glucosyl-(1->2)-beta-D-glucoside]
C12637 Quercetin 3-O-[beta-D-xylosyl-(1->2)-beta-D-glucoside]
C12638 Quercetin 3-O-(6-O-malonyl-beta-D-glucoside)
C12667 Quercetin 3-O-beta-D-glucosyl-(1->2)-beta-D-glucoside
C12668 Quercetin 3-sophorotrioside
C16490 Kaempferol 3-O-beta-D-glucosylgalactoside
C19796 Quercetin 3-O-rhamnoside 7-O-glucoside
C21833 Kaempferol-3-O-rutinoside
C21854 Kaempferol 3-O-rhamnoside-7-O-glucoside
Reference
Authors
De Luca V, Ibrahim RK
Title
Enzymatic synthesis of polymethylated flavonols in Chrysosplenium americanum. I. Partial purification and some properties of S-adenosyl-L-methionine:flavonol 3-, 6-, 7-, and 4'-O-methyltransferases.
Journal
Reference
Authors
Jourdan PS, Mansell RL
Title
Isolation and partial characterization of three glucosyl transferases involved in the biosynthesis of flavonol triglucosides in Pisum sativum L.
Journal
Reference
Authors
Miller KD, Guyon V, Evans JN, Shuttleworth WA, Taylor LP
Title
Purification, cloning, and heterologous expression of a catalytically efficient flavonol 3-O-galactosyltransferase expressed in the male gametophyte of Petunia hybrida.
Journal
Reference
Authors
Cacace S, Schroder G, Wehinger E, Strack D, Schmidt J, Schroder J
Title
A flavonol O-methyltransferase from Catharanthus roseus performing two sequential methylations.
Journal
Reference
Authors
Tohge T, Nishiyama Y, Hirai MY, Yano M, Nakajima J, Awazuhara M, Inoue E, Takahashi H, Goodenowe DB, Kitayama M, Noji M, Yamazaki M, Saito K
Title
Functional genomics by integrated analysis of metabolome and transcriptome of Arabidopsis plants over-expressing an MYB transcription factor.
Journal
Reference
Authors
Kubo H, Nawa N, Lupsea SA
Title
Anthocyaninless1 gene of Arabidopsis thaliana encodes a UDP-glucose:flavonoid-3-O-glucosyltransferase.
Journal
Reference
Authors
Knogge W, Weissenbock G
Title
Tissue-distribution of secondary phenolic biosynthesis in developing primary leaves of Avena sativa L.
Journal
Reference
Authors
Anhalt S, Weissenbock G
Title
Subcellular localization of luteolin glucuronides and related enzymes in rye mesophyll.
Journal
Reference
Authors
Suzuki H, Nakayama T, Nagae S, Yamaguchi M, Iwashita T, Fukui Y, Nishino T.
Title
cDNA cloning and functional characterization of flavonol 3-O-glucoside-6"-O-malonyltransferases from flowers of Verbena hybrida and Lamium purpureum.
Journal
Related pathway
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