KEGG ORTHOLOGY: K08622

ORTHOLOGY: K08622

Entry

K08622                      KO

Symbol

ADAMTS7

Name

a disintegrin and metalloproteinase with thrombospondin motifs 7 [EC:3.4.24.-]

Brite

KEGG Orthology (KO) [BR:ko00001]
09180 Brite Hierarchies
  09181 Protein families: metabolism
   01002 Peptidases and inhibitors
    K08622  ADAMTS7; a disintegrin and metalloproteinase with thrombospondin motifs 7
Peptidases and inhibitors [BR:ko01002]
Metallo peptidases
  Family M12: astacin/adamalysin family
   K08622  ADAMTS7; a disintegrin and metalloproteinase with thrombospondin motifs 7

Genes

HSA:	11173(ADAMTS7)

PTR:	467749(ADAMTS7) 743568

PPS:	100976854 117976079(ADAMTS7) 129393975 129394029 134729056 134729057 134729058 134729059 134729060 134729061

GGO:	101152367(ADAMTS7) 109023513

PON:	100443530(ADAMTS7) 100450902 100452234

PPYG:

129013575(ADAMTS7) 129013878 129013882

NLE:	100601500(ADAMTS7)

HMH:

116481566

SSYN:

129481539 129482177(ADAMTS7)

MCC:	711193(ADAMTS7)

MCF:	123566778(ADAMTS7)

MTHB:

126960074

MNI:	105493127(ADAMTS7)

CATY:

105571744(ADAMTS7) 105600679

PANU:

101004454(ADAMTS7) 101027039

TGE:	112627860(ADAMTS7)

MLEU:

105542264 105542268(ADAMTS7)

RRO:	104662172(ADAMTS7)

TFN:

117070328

PTEH:

111534874

CANG:

105509265(ADAMTS7) 105525744

CJC:

100412393

CIMI:

108295091 108296555 108296747(ADAMTS7) 108298259

ANAN:

105732649(ADAMTS7)

CSYR:

103258597(ADAMTS7)

MMUR:

105856553(ADAMTS7)

LCAT:

123644643(ADAMTS7)

PCOQ:

105822752(ADAMTS7)

OGA:	100945540(ADAMTS7)

MMU:	108153(Adamts7)

MCAL:

110302406(Adamts7)

MPAH:

110327409(Adamts7)

RNO:	315879(Adamts7)

MCOC:

116073584(Adamts7)

ANU:	117693393(Adamts7)

ASYL:

127688724(Adamts7)

MUN:	110549498(Adamts7)

CGE:	100756390(Adamts7)

MAUA:

101827262(Adamts7)

PROB:

127238695(Adamts7)

PLEU:

114690945(Adamts7)

MORG:

121464365(Adamts7)

MFOT:

126510628

AAMP:

119809600(Adamts7)

NGI:	103726054(Adamts7)

HGL:	101710586(Adamts7)

CPOC:

100728771(Adamts7)

DORD:

105982380(Adamts7)

DSP:	122123428(Adamts7)

NCAR:

124975990

MMMA:

107137900(Adamts7)

ITI:	101962047(Adamts7)

OCU:

100340872

OPI:	101533386(ADAMTS7)

GVR:	103601853(ADAMTS7)

CFA:	488775(ADAMTS7)

CLUD:

112653965(ADAMTS7)

VVP:	112922763(ADAMTS7)

VLG:	121490060(ADAMTS7)

NPO:	129510627(ADAMTS7)

AML:	100481511(ADAMTS7)

UMR:	103660315(ADAMTS7)

UAH:	125282853(ADAMTS7)

UAR:	123796884(ADAMTS7)

ELK:

111152559

LLV:

125103815

MPUF:

101670058(ADAMTS7)

MNP:	132029222(ADAMTS7)

MLK:	131835481(ADAMTS7)

NVS:	122894698(ADAMTS7)

ORO:	101369024(ADAMTS7)

EJU:	114201263(ADAMTS7)

ZCA:	113908802(ADAMTS7)

MLX:	118023171(ADAMTS7)

NSU:	110572216(ADAMTS7)

LWW:	102744775(ADAMTS7)

FCA:	101092185(ADAMTS7)

PBG:	122468164(ADAMTS7)

PVIV:

125159010(ADAMTS7)

LRUF:

124527851

LGF:	123582382(ADAMTS7)

AJU:

113601999

PPAD:

109273306(ADAMTS7)

PUC:

125910727

PLEZ:

122221495(ADAMTS7)

HHV:	120219891(ADAMTS7)

BTA:	504694(ADAMTS7)

BOM:	102283528(ADAMTS7)

BIU:	109575188(ADAMTS7)

BBUB:

102415531(ADAMTS7)

BBIS:

104991039(ADAMTS7)

CHX:	102186909(ADAMTS7)

OAS:	101114142(ADAMTS7)

BTAX:

128066668(ADAMTS7)

CSUM:

138094972(ADAMTS7)

ODA:	120875514(ADAMTS7)

CCAD:

122419731(ADAMTS7)

MREE:

136147099(ADAMTS7)

OVR:	110131321(ADAMTS7)

MBEZ:

129550395(ADAMTS7)

SSC:	100154398(ADAMTS7)

CFR:	102506674(ADAMTS7)

CBAI:

105069143(ADAMTS7)

CDK:	105092240(ADAMTS7)

VPC:	102534019(ADAMTS7)

BACU:

103011709(ADAMTS7)

BMUS:

118889819(ADAMTS7)

LVE:	103086328(ADAMTS7)

OOR:	101280629(ADAMTS7)

LALB:

132523703(ADAMTS7)

DLE:	111177883(ADAMTS7)

PCAD:

102978331(ADAMTS7)

PSIU:

116749677(ADAMTS7)

NASI:

112405771(ADAMTS7)

ECB:	100059959(ADAMTS7)

EPZ:	103559014(ADAMTS7)

EAI:	106840818(ADAMTS7)

MMYO:

118679118(ADAMTS7)

MDT:	132222737(ADAMTS7)

PKL:	118719735(ADAMTS7)

EFUS:

103303837(ADAMTS7)

DRO:	112306149(ADAMTS7)

SHON:

118991859(ADAMTS7)

AJM:	119057263(ADAMTS7)

PDIC:

114488698(ADAMTS7)

PHAS:

123809808(ADAMTS7)

MMF:	118641012(ADAMTS7)

PPAM:

129082873(ADAMTS7)

HAI:	109381488(ADAMTS7)

RFQ:	117018780(ADAMTS7)

PALE:

102889866(ADAMTS7)

PGIG:

120599321(ADAMTS7)

PVP:	105301642(ADAMTS7)

RAY:	107500378(ADAMTS7)

TOD:	119245128(ADAMTS7)

SARA:

101557287(ADAMTS7)

SFUM:

130023406(ADAMTS7)

SETR:

126021982(ADAMTS7)

LAV:	100661729(ADAMTS7)

TMU:

101360618

ETF:	101655006(ADAMTS7)

DNM:	101421417(ADAMTS7)

MDO:	100026396(ADAMTS7)

GAS:	123234383(ADAMTS7)

SHR:	100927114(ADAMTS7)

AFZ:

127552040

PCW:	110200617(ADAMTS7)

TVP:	118828969(ADAMTS7)

PBRV:

138148606(ADAMTS7)

OAA:	100086116(ADAMTS7)

TACU:

119945813(ADAMTS7)

GGA:	415570(ADAMTS7)

PCOC:

116225500(ADAMTS7)

MGP:	100549682(ADAMTS7)

CJO:	107318908(ADAMTS7)

TPAI:

128075118(ADAMTS7)

LMUT:

125698018(ADAMTS7)

NMEL:

110403884(ADAMTS7)

APLA:

101791383(ADAMTS7)

ACYG:

106043633(ADAMTS7)

CATA:

118259425(ADAMTS7)

AFUL:

116493450(ADAMTS7)

TGU:	100225113(ADAMTS7)

LSR:	110477565(ADAMTS7)

SCAN:

103816265(ADAMTS7)

PMOA:

120508942(ADAMTS7)

OTC:	121343373(ADAMTS7)

PRUF:

121354345(ADAMTS7)

ATRC:

139596667(ADAMTS7)

OMA:	130257523(ADAMTS7)

PHI:	102107658(ADAMTS7)

PMAJ:

107209142(ADAMTS7)

CCW:	104684057(ADAMTS7)

CBRC:

103619765(ADAMTS7)

ACOE:

138116624(ADAMTS7)

ETL:	114067180(ADAMTS7)

ZLE:	135452445(ADAMTS7)

ACHL:

103802316

SVG:	106860107(ADAMTS7)

MMEA:

130582549(ADAMTS7)

HRT:	120758615(ADAMTS7)

SATI:

136366816(ADAMTS7)

CCIC:

134049014(ADAMTS7)

FPG:	101923188(ADAMTS7)

FCH:	102056796(ADAMTS7)

CCRI:

104164217(ADAMTS7)

SHAB:

115612761(ADAMTS7)

ACUN:

113483963(ADAMTS7)

TALA:

116959105(ADAMTS7)

ACHC:

115341951(ADAMTS7)

HLE:	104834755(ADAMTS7)

AGEN:

126043918

HHAR:

128151230(ADAMTS7)

GCL:

127020773

DPUB:

104305815(ADAMTS7)

PPUS:

135183046(ADAMTS7)

EGZ:	104132134(ADAMTS7)

NNI:	104017194(ADAMTS7)

PADL:

103914798

AFOR:

103899906(ADAMTS7)

CBOY:

140655902(ADAMTS7)

CLV:	102088575(ADAMTS7)

MUI:

104548098

EHS:	104516483(ADAMTS7)

CUCA:

104065202(ADAMTS7)

ACAR:

104529773

CPEA:

104393364(ADAMTS7)

CVF:	104283021(ADAMTS7)

RTD:	128915022(ADAMTS7)

CRID:

134520670(ADAMTS7)

AAM:	106484425(ADAMTS7)

AROW:

112963558(ADAMTS7)

NPD:	112948390(ADAMTS7)

TGT:	104570355(ADAMTS7)

DNE:	112987927(ADAMTS7)

SCAM:

104151502(ADAMTS7)

AMJ:	102567674(ADAMTS7)

CPOO:

109309230(ADAMTS7)

GGN:	109288290(ADAMTS7)

PSS:	102460053(ADAMTS7)

CMY:	102937796(ADAMTS7)

CCAY:

125644060(ADAMTS7)

DCC:	119862992(ADAMTS7)

CPIC:

101932984(ADAMTS7)

TST:	117884519(ADAMTS7)

CABI:

116815748(ADAMTS7)

MRV:	120373053(ADAMTS7)

ACS:	100558772(adamts7)

ASAO:

132762435(ADAMTS7)

PVT:	110089862(ADAMTS7)

SUND:

121933241(ADAMTS7)

PBI:

103059333

PMUR:

107283904(ADAMTS7)

CTIG:

120316408(ADAMTS7)

TSR:	106547930(ADAMTS7)

APRI:

131184463(ADAMTS7)

PTEX:

113441985

NSS:	113425681(ADAMTS7)

VKO:	123030753(ADAMTS7)

PMUA:

114584018(ADAMTS7)

PRAF:

128401771(ADAMTS7)

ZVI:	118093010(ADAMTS7)

HCG:	128334690(ADAMTS7)

GJA:	107116559(ADAMTS7)

EMC:	129345601(ADAMTS7)

XLA:	108711515(adamts7.L)

XTR:	100491770(adamts7)

NPR:

108796025

RTEM:

120931079(ADAMTS7)

BBUF:

120986048(ADAMTS7)

BGAR:

122927472

PWL:	138284312(ADAMTS7)

MUO:	115459960(ADAMTS7)

GSH:	117348231(ADAMTS7)

DRE:

560364

SRX:	107730163 107738910

SANH:

SGH:

CCAR:

CAUA:

CGIB:

PTET:

LROH:

OMC:

PPRM:

RKG:

MAMB:

CIDE:

CERY:

MASI:

TROS:

TDW:

MANU:

PDAB:

IPU:

IFU:

PHYP:

113536575(adamts7)

SMEO:

TFD:

TVC:

CGAR:

NGRA:

TRN:

AMEX:

CMAO:

EEE:

CHAR:

SPIL:

TRU:	101076359(adamts7)

TFS:

130521913

TNG:	GSTEN00018130G001

LCO:

104920626

NCC:	104955849(adamts7)

TBEN:

CGOB:

PGEO:

GACU:

EMAC:

ELY:

EFO:

PLEP:

SLUC:

ECRA:

ESP:

PFLV:

GAT:

PPUG:

AFB:

CLUM:

PSWI:

CANA:

CVE:

MSAM:

SCHU:

CUD:

SPUL:

LMIX:

ALAT:

ASTR:

ONL:

OAU:

OLA:

OML:

CSAI:

XMA:

XCO:	114143061(adamts7)

XHE:

116718638

PRET:

103462126(adamts7)

PFOR:

103135945(adamts7)

PLAI:

106952188(adamts7)

PMEI:

106921103(adamts7)

GAF:

PPRL:

CVG:

CTUL:

GMU:

NFU:

KMR:

ALIM:

106512975(adamts7)

NWH:

AOCE:

EJA:

BFRE:

MCEP:

CSEM:

103398480(adamts7)

POV:	109637276(adamts7)

SSEN:

SSOE:

HHIP:

HSP:

PPLT:

SMAU:

LCF:

SDU:

SLAL:

XGL:

HCQ:

SSCV:

SBIA:

PEE:

PTAO:

ENY:	140380783(adamts7)

MALB:

BSPL:

SJO:

SSCO:

GMH:

SASA:

STRU:

115167442 115202536(adamts7)

OTW:

112264251

OMY:	110513865 110515416

OGO:	124022070 124035397

OKI:	109877978(adamts7)

OKE:

118372296

OMM:

135556025

OCLA:

139384817 139384852 139411724

SNH:

CCLU:

ELS:

OEP:

SFM:

PKI:

AANG:

AROT:

CCOG:

LOC:

PSPA:

ARUT:

PSEX:

LCM:	102362239(ADAMTS7)

CMK:

RTP:

CPLA:

HOC:

LERI:

PMRN:

LRJ:	133346657 133355025

CIN:

SCLV:

SPU:

LPIC:

AJJ:

AAMU:

AFIL:

PFLL:

PJA:

PCHN:

HAME:

PTRU:

ESN:

MRJ:

HAZT:

PPOI:

DSV:

RSAN:

RMP:

VJA:

CVS:

ABRU:

SDM:

LPOL:

LSAX:

BGT:

HRF:	124134126 124145569

HRJ:

HASI:

HCRA:

MMER:

RPHI:

MAEA:

LLON:

NVE:

MCAZ:

MFOO:

SPIS:

RES:

Reference

PMID:15987500

Authors

Jones GC, Riley GP

Title

ADAMTS proteinases: a multi-domain, multi-functional family with roles in extracellular matrix turnover and arthritis.

Journal

Arthritis Res Ther 7:160-9 (2005)
DOI:10.1186/ar1783

Reference

PMID:16585064

Authors

Liu CJ, Kong W, Ilalov K, Yu S, Xu K, Prazak L, Fajardo M, Sehgal B, Di Cesare PE

Title

ADAMTS-7: a metalloproteinase that directly binds to and degrades cartilage oligomeric matrix protein.

Journal

FASEB J 20:988-90 (2006)
DOI:10.1096/fj.05-3877fje

Sequence

[hsa:11173]

LinkDB

DBGET integrated database retrieval system