Lagenorhynchus albirostris (white-beaked dolphin): 132526580
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Entry
132526580 CDS
T10760
Symbol
TH
Name
(RefSeq) tyrosine 3-monooxygenase isoform X1
KO
K00501
tyrosine 3-monooxygenase [EC:
1.14.16.2
]
Organism
lalb Lagenorhynchus albirostris (white-beaked dolphin)
Pathway
lalb00350
Tyrosine metabolism
lalb00790
Folate biosynthesis
lalb01100
Metabolic pathways
lalb04728
Dopaminergic synapse
lalb04917
Prolactin signaling pathway
lalb05012
Parkinson disease
lalb05030
Cocaine addiction
lalb05031
Amphetamine addiction
lalb05034
Alcoholism
Module
lalb_M00042
Catecholamine biosynthesis, tyrosine => dopamine => noradrenaline => adrenaline
Brite
KEGG Orthology (KO) [BR:
lalb00001
]
09100 Metabolism
09105 Amino acid metabolism
00350 Tyrosine metabolism
132526580 (TH)
09108 Metabolism of cofactors and vitamins
00790 Folate biosynthesis
132526580 (TH)
09150 Organismal Systems
09152 Endocrine system
04917 Prolactin signaling pathway
132526580 (TH)
09156 Nervous system
04728 Dopaminergic synapse
132526580 (TH)
09160 Human Diseases
09164 Neurodegenerative disease
05012 Parkinson disease
132526580 (TH)
09165 Substance dependence
05030 Cocaine addiction
132526580 (TH)
05031 Amphetamine addiction
132526580 (TH)
05034 Alcoholism
132526580 (TH)
Enzymes [BR:
lalb01000
]
1. Oxidoreductases
1.14 Acting on paired donors, with incorporation or reduction of molecular oxygen
1.14.16 With reduced pteridine as one donor, and incorporation of one atom of oxygen into the other donor
1.14.16.2 tyrosine 3-monooxygenase
132526580 (TH)
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Motif
Pfam:
Biopterin_H
TH_ACT
TOH_N
LTP_2
Motif
Other DBs
NCBI-GeneID:
132526580
NCBI-ProteinID:
XP_060016904
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Position
9:complement(1574066..1581025)
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AA seq
500 aa
AA seq
DB search
MPTPNAASPQAKGFRRAVSELDAKQAEAIMVRGRLSPRFVGRRQSLIQDARNERQKAEAA
AAAAAAAAAAEPGETLGGRAGKAALNLLFTLRATKPPALSRAVKVFETFEAQIHHLETRP
AQKPQAGGPHLEYFVRCEVPSAALPTLLSSLRRVAEDVRGAGENKVLWFPRKVSELDKCH
HLVTKFDPDLDLDHPGFSDQVYRQRRKLIAEIAFQYKQGDPIPHVEYTAEETATWKEVYT
TLRGLYATHACREHLEAFELLEHFCGYREDSIPQLEDVSRFLKERTGFQLRPVAGLLSAR
DFLASLAFRVFQCTQYIRHASSPMHSPEPDCCHELLGHVPMLADRTFAQFSQDIGLASLG
ASDEEIEKLSTLYWFTVEFGLCKQNGEVKAYGAGLLSSYGELLHSLSEEPEIRAFDPDAA
AVQPYQDQTYQPVYFVSESFSDAKDKLRSYASRIQRPFSVKFDPYTLAIDVLDSPHAIQR
ALDGVRDELHALTHALSAIS
NT seq
1503 nt
NT seq
+upstream
nt +downstream
nt
atgcccacccccaacgctgcctcgccgcaggccaagggcttccgcagggccgtctccgag
ctggacgccaagcaggccgaggccatcatggtaagaggcaggctgtccccacgcttcgtc
gggaggcggcagagcctcatccaggatgcccgcaacgagcgacagaaggcggaggccgcc
gccgccgccgccgccgccgctgccgccgcggagccgggcgagaccctggggggacgggcc
gggaaggccgcgctgaatctcctcttcaccctgcgggccaccaagccccccgcgctgtcc
cgggctgtgaaggtgtttgagacatttgaagcccaaatccaccacctggagacccggccc
gcccagaagccgcaggcagggggcccgcacctggagtacttcgtgcgctgtgaggtaccc
agcgccgccctgcccaccctgctcagctcccttcgccgcgtggccgaagacgtgcggggc
gctggggagaacaaggtcctctggttcccaaggaaagtttctgagctggacaagtgtcac
cacctggtcaccaagtttgaccctgacctggacttggaccatccgggcttctcggaccag
gtgtaccgccagcgcaggaagctgattgctgagatcgccttccagtacaagcaaggcgac
cctattccccacgtggagtacacggccgaggagactgccacctggaaggaggtctacacc
acgctgcggggcctctacgccacccacgcgtgccgggaacacctggaggctttcgagctg
ctggagcacttctgcgggtaccgggaggacagcatcccccagctggaggacgtctcccgc
ttcctgaaggagcggaccggcttccagctgcggcccgtggccggcctgctgtccgcccgg
gacttcctggccagcctggccttccgcgtgttccagtgcacccagtacatccgccatgcc
tcctcacccatgcactcccccgagccggactgctgccacgagctgctggggcacgtgccc
atgctggccgaccggaccttcgcccagttctcccaggacatcggcctcgcatccctgggg
gcatcggacgaggaaattgagaagctgtccacgctgtactggttcaccgtggagtttggg
ctgtgcaaacagaacggcgaggtgaaggcctacggagcggggctgctgtcctcctatggg
gagctcctgcattccctgtctgaggagcccgagatccgggccttcgaccccgacgcagcg
gccgtgcagccctaccaggaccagacttatcaacctgtctacttcgtgtctgagagcttc
agcgacgccaaggacaaactcaggagctatgcctcccgcatccagcgccccttctccgtg
aagttcgacccatacacgctggccatcgatgtgctggacagcccccacgccatccaacgc
gccctggatggtgtccgggacgagctgcacgccctcacccacgccctgagcgccatcagc
tag
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