Leopardus geoffroyi (Geoffroy's cat): 123597189
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Entry
123597189 CDS
T10761
Symbol
MTHFR
Name
(RefSeq) methylenetetrahydrofolate reductase isoform X1
KO
K25004
methylenetetrahydrofolate reductase (NADPH) [EC:
1.5.1.53
]
Organism
lgf Leopardus geoffroyi (Geoffroy's cat)
Pathway
lgf00670
One carbon pool by folate
lgf01100
Metabolic pathways
lgf01523
Antifolate resistance
lgf04981
Folate transport and metabolism
Brite
Enzymes [BR:
lgf01000
]
1. Oxidoreductases
1.5 Acting on the CH-NH group of donors
1.5.1 With NAD+ or NADP+ as acceptor
1.5.1.53 methylenetetrahydrofolate reductase (NADPH)
123597189 (MTHFR)
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Motif
Pfam:
MTHFR_C
MTHFR
DUF6919
Motif
Other DBs
NCBI-GeneID:
123597189
NCBI-ProteinID:
XP_045331597
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Position
C1:complement(8637159..8650846)
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AA seq
720 aa
AA seq
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MDHPTPKVLLARPRCPSLRMWALEASSGRFSVPPSISISHLTLPLRVLAACPLTLLPSTP
CSRNPAMVNEPRGDGGPTSRSEGSSSGSESSKDSSRCSTPGLDPERHDRLREKMRRRMES
GDKWFSLEFFPPRTAQGAVNLISRFDRMGAGGPLFIDVTWHPAGDPGSDKETSSMVIAST
AVNYCGLETILHMTCCCQSREQITGYLHKAKRLGLKNILALRGDPVGDQWEEEEGGFSYA
ADLVRHIRSEFGDYFDVCVAGYPKGHPDAGSFEADLKYLKEKVSAGADFIITQLFFEADT
FFHFVKACSEIGITCPILPGIFPIQGYHSLRQLVKLSKLEVPQQIKDVIEPIKDNDAAIR
NYGIEQAVSLCQELLTSGSVPGLHFYTLNREMATTEVLKRLGMWIEDPRRPLPWAVSAHP
KRREEDVRPIFWASRPKSYIYRTQEWDEFPNGRWGNSSSPAFGELKDYYLFYLTSKSPRE
ELLKMWGEELTGEESVFEVFACYLSGEPNQNGYKVTCLPWNDEPLAAETSLMKEELLRVN
RQGILTINSQPNINGKPSSDPIVGWGPSGGYVFQKAYLEFFTSRETVGALLQVLKKYELR
VNYHIVDVKGENVTNAPELQPNAVTWGIFPGREIIQPTVVDPVSFMFWKDEAFALWIEQW
GKLYEEESPSRMIIQYIHDNYFLVNLVDNEFPLDNCLWQVVEDTFELLNRPGPEQETETL
NT seq
2163 nt
NT seq
+upstream
nt +downstream
nt
atggaccatccaacacccaaggtcctcctagccaggccccgctgcccctccctacgaatg
tgggctttggaggccagcagcgggaggttctcagtgccaccctccatcagcatctctcac
ttgaccctgccactccgggtcctggctgcctgccctctgacgctcctgccctccaccccg
tgcagcaggaacccggccatggtgaacgaacccagaggggatggtggccccacgtcccgc
tcggagggcagcagcagtggcagcgagagctccaaggatagttcgagatgttccacgccg
gggctggaccccgagcgccacgacagactcagggagaagatgaggcggaggatggaatct
ggtgacaagtggttctccctagaattcttccctcctcggaccgctcagggagccgtcaat
ctcatctcgaggtttgatcggatgggggcaggtggccccctcttcatagatgtgacctgg
cacccggcaggggatcccggctcagacaaggagacctcctccatggtgatcgccagcacc
gccgtgaactactgtggcctggagaccatcctgcacatgacctgctgctgtcagagccgg
gaacagatcacaggctatctgcacaaggccaagcggctgggcctgaagaacatcttggcg
ttgaggggagaccccgtgggtgaccagtgggaagaggaggaaggaggcttcagctatgct
gcagacttggtgaggcacatccgaagcgagtttggagactactttgacgtctgtgtggca
ggttaccccaaaggccaccccgacgcagggagctttgaggccgacctgaagtacttgaag
gagaaggtatccgcaggagccgacttcatcatcacccagcttttctttgaggctgacaca
ttcttccactttgttaaggcttgcagcgagataggcattacctgccccatcctccccgga
atctttcctatccagggctaccactcccttcggcagcttgtgaaactgtccaagctggag
gtaccgcagcagatcaaggacgtgatcgagccaatcaaagacaatgacgctgccatccgc
aactatggcatcgagcaggctgtgagcctgtgccaggagcttctgaccagtggctcggtg
ccaggccttcacttctacaccctcaaccgcgagatggccaccacagaggtgctgaagcgc
ctgggcatgtggattgaggaccccaggcgtcccctgccctgggccgtcagtgcccacccc
aagcgccgggaggaggacgtgcgtcccatcttctgggcctccagaccaaagagttacatc
taccgcacccaggagtgggatgagttccccaacggccgctggggcaattcctcctctcca
gccttcggggagctgaaggactactacctcttctacctgacgagcaagtccccgagggag
gagctgctgaagatgtggggggaggagctgaccggggaagaaagcgtctttgaagtcttt
gcctgctacctctcgggagagcccaaccagaatggctataaggtgacttgcctgccctgg
aatgacgagcccttggcggccgagaccagcctgatgaaggaggagctgcttcgagtgaac
cggcagggcatcctcaccatcaactcccagcccaacatcaacgggaagccatcctctgac
cccattgtgggctggggccccagtgggggctatgtcttccagaaggcctacttggagttc
tttacttcccgtgagacggtgggggcgcttctgcaggtgctgaagaagtatgagctccgg
gttaattaccacatcgtggatgtgaagggtgaaaacgtcaccaatgcccccgagctgcag
cccaatgcagtcacttggggcatcttccctgggcgagaaatcatccagcctacagtggtg
gatcctgtcagcttcatgttctggaaggatgaagcctttgccctgtggatcgagcagtgg
ggcaagctgtatgaggaggagtctccgtcccgcatgatcatccagtacatccacgacaac
tacttcctggtcaacctggtagataacgagtttccgctggacaactgcctgtggcaagtg
gtagaagacacgtttgagcttctcaacagacccgggccagagcaggagacagagaccctg
tga
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