Leopardus geoffroyi (Geoffroy's cat): 123602094 Help Entry 123602094         CDS       T10761                                  Symbol TH Name (RefSeq) tyrosine 3-monooxygenase   KO K00501   tyrosine 3-monooxygenase [EC:1.14.16.2] Organism lgf  Leopardus geoffroyi (Geoffroy's cat) Pathway lgf00350   Tyrosine metabolism lgf00790   Folate biosynthesis lgf01100   Metabolic pathways lgf04728   Dopaminergic synapse lgf04917   Prolactin signaling pathway lgf05012   Parkinson disease lgf05030   Cocaine addiction lgf05031   Amphetamine addiction lgf05034   Alcoholism Module lgf_M00042   Catecholamine biosynthesis, tyrosine => dopamine => noradrenaline => adrenaline Brite KEGG Orthology (KO) [BR:lgf00001]  09100 Metabolism   09105 Amino acid metabolism    00350 Tyrosine metabolism     123602094 (TH)   09108 Metabolism of cofactors and vitamins    00790 Folate biosynthesis     123602094 (TH)  09150 Organismal Systems   09152 Endocrine system    04917 Prolactin signaling pathway     123602094 (TH)   09156 Nervous system    04728 Dopaminergic synapse     123602094 (TH)  09160 Human Diseases   09164 Neurodegenerative disease    05012 Parkinson disease     123602094 (TH)   09165 Substance dependence    05030 Cocaine addiction     123602094 (TH)    05031 Amphetamine addiction     123602094 (TH)    05034 Alcoholism     123602094 (TH) Enzymes [BR:lgf01000]  1. Oxidoreductases   1.14  Acting on paired donors, with incorporation or reduction of molecular oxygen    1.14.16  With reduced pteridine as one donor, and incorporation of one atom of oxygen into the other donor     1.14.16.2  tyrosine 3-monooxygenase      123602094 (TH) BRITE hierarchy SSDB OrthologParalogGene clusterGFIT Motif Pfam:  Biopterin_H TH_ACT TOH_N LTP_2 Motif Other DBs NCBI-GeneID:  123602094 NCBI-ProteinID:  XP_045342279 LinkDB All DBs Position D1:113993027..114000450 Genome browser AA seq 494 aa AA seqDB search MPTPNAASPQAKGFRRAVSELDAKQAEAIMSPRFIGRRQSLIEDARKEREKAEAAGAASS EPGDPLETAVFKEKDGKATLNLIFTLRGAKASLSRAVKVFETFEAQIRHLETRPAQRPRA GGPRLEYFVCCQVPSADLPALLSSVRRVAEDVRGARENKVFWFPRKVSELDKCHHLVTKF DPDLDLGHPGFSDQAYRQRRKLIAEIAFQYKHGDPIPRVEYTAEEIATWKEVYTTLKGLY VTHACREHLEAFQLLERFSGYREDSIPQLEDVSRFLKERTGFQLRPVAGLLSARDFLASL AFRVFQCTQYIRHASSPMHSPEPDCCHELLGHVPMLADRTFAQFSQDIGLASLGASDEEI EKLSTLYWFTVEFGLCKQNGEVKAYGAGLLSSYGELLHSLSEEPEIRAFDPDAAAVQPYQ DQTYQPVYFVSESFSDAKDKLRNYASRIQRPFSVKFDPYTLAIDVLDSPHAIRRSLQGVQ DELHTLTHALSAIG NT seq 1485 nt NT seq  +upstreamnt  +downstreamnt atgcccactcccaacgccgcctcgccgcaggccaagggcttccgcagggccgtctccgag ctggacgccaagcaggccgaagccatcatgtccccgcgcttcatcgggcgacggcagagc ctcatcgaggacgctcgcaaggagcgagagaaggcagaggccgcgggggccgcctcctca gagcctggggaccccctggagaccgcagtgttcaaggagaaggacggaaaggccacactc aacttgatcttcaccctgcggggcgccaaagcctcactgtcccgggccgtgaaggtgttc gagacgtttgaggcccaaatccggcacctggagacccggccggcccagaggccgcgcgca gggggcccccgcctggaatacttcgtgtgctgtcaggtacccagcgcggacctgcccgcc ctgctcagctccgtgcgccgggtggctgaggacgtgcggggtgccagggagaacaaagtc ttctggttcccgaggaaagtttccgagctggacaagtgccaccacctggtcaccaagttt gaccctgacctggacctgggtcacccgggtttctcggaccaggcctaccggcagcgcagg aagctgatcgccgagatagcctttcagtacaagcatggcgaccccattccccgtgtggag tacacggccgaggagatcgccacctggaaggaggtctacaccaccctcaagggcctctac gtcactcacgcctgccgggaacacttggaggctttccagctgctggagcgtttcagcggg taccgggaggacagcatccctcagctggaagacgtgtcccgcttcctgaaggaacggaca gggttccagctgcggcccgtggccggcctgctgtccgcccgggacttcctggccagcctg gccttccgagtgttccagtgcacccagtacatccgacacgcctcctcgcccatgcactcc ccggagccggactgctgccacgagctgctggggcacgtgcccatgctggccgaccgcacc ttcgctcagttctcccaggacattgggctcgcgtccttgggggcttccgacgaggagatt gagaagctgtccacgctgtactggttcacggtggagttcgggctgtgcaaacagaatggg gaggtgaaggcctacggtgctggactgctgtcctcctacggggagctcctgcactctctg tctgaggagcccgagatccgggccttcgacccggatgctgcagccgtacagccttaccag gaccagacttaccagcccgtctacttcgtgtccgagagtttcagcgacgccaaggacaaa ctcaggaactatgcttcccgcatccagcgccccttctctgtgaagtttgacccgtacacg ctggccatcgacgtgctggacagtccccatgccatccggcgctccctgcagggcgtccag gacgagctgcacaccctcacccatgcgctgagcgccatcggctag

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