KEGG   Lipotes vexillifer (Yangtze River dolphin): 103086024
Entry
103086024         CDS       T03090                                 
Symbol
TH
Name
(RefSeq) tyrosine 3-monooxygenase
  KO
K00501  tyrosine 3-monooxygenase [EC:1.14.16.2]
Organism
lve  Lipotes vexillifer (Yangtze River dolphin)
Pathway
lve00350  Tyrosine metabolism
lve00790  Folate biosynthesis
lve01100  Metabolic pathways
lve04728  Dopaminergic synapse
lve04917  Prolactin signaling pathway
lve05012  Parkinson disease
lve05030  Cocaine addiction
lve05031  Amphetamine addiction
lve05034  Alcoholism
Module
lve_M00042  Catecholamine biosynthesis, tyrosine => dopamine => noradrenaline => adrenaline
Brite
KEGG Orthology (KO) [BR:lve00001]
 09100 Metabolism
  09105 Amino acid metabolism
   00350 Tyrosine metabolism
    103086024 (TH)
  09108 Metabolism of cofactors and vitamins
   00790 Folate biosynthesis
    103086024 (TH)
 09150 Organismal Systems
  09152 Endocrine system
   04917 Prolactin signaling pathway
    103086024 (TH)
  09156 Nervous system
   04728 Dopaminergic synapse
    103086024 (TH)
 09160 Human Diseases
  09164 Neurodegenerative disease
   05012 Parkinson disease
    103086024 (TH)
  09165 Substance dependence
   05030 Cocaine addiction
    103086024 (TH)
   05031 Amphetamine addiction
    103086024 (TH)
   05034 Alcoholism
    103086024 (TH)
Enzymes [BR:lve01000]
 1. Oxidoreductases
  1.14  Acting on paired donors, with incorporation or reduction of molecular oxygen
   1.14.16  With reduced pteridine as one donor, and incorporation of one atom of oxygen into the other donor
    1.14.16.2  tyrosine 3-monooxygenase
     103086024 (TH)
SSDB
Motif
Pfam: Biopterin_H TH_ACT TOH_N LTP_2
Other DBs
NCBI-GeneID: 103086024
NCBI-ProteinID: XP_007466016
UniProt: A0A340XXD3
LinkDB
Position
Unknown
AA seq 492 aa
MPTPNAASPQAKGFRRAVSELDAKQAEAIMSPRFVGRRQSLIQDARNERQKAEAAAAAAA
AAEPGEALGGRAGKAALNLLFALRATKPPALSRAVKVFETFEAQIHHLETRPAQKPQAGG
PHLEYFVRCEVPSAALPTLLSSLRRVAEDVRGAGENKVLWFPRKVSELDKCHHLVTKFDP
DLDLDHPGFSDQVYRQRRKLIAEIAFQYKQGDPIPHVEYTAEETATWKEVYTTLRGLYAT
HACREHLEAFELLEHFCGYREDSIPQLEDVSRFLKERTGFQLRPVAGLLSARDFLASLAF
RVFQCTQYIRHASSPMHSPEPDCCHELLGHVPMLADRTFAQFSQDIGLASLGASDEEIEK
LSTLYWFTVEFGLCKQNGEVKAYGAGLLSSYGELLHSLSEGPEIRAFDPDAAAVQPYQDQ
TYQPVYFVSESFSDAKDKLRSYASRIQRPFSVKFDPYTLAIDVLDSPHAIRRALDGVQDE
LHALTHALSAIS
NT seq 1479 nt   +upstreamnt  +downstreamnt
atgcccacccccaatgctgcctcgccgcaggccaagggcttccgcagggccgtctccgag
ctggacgccaagcaggccgaggccatcatgtccccacgcttcgtcgggaggcggcagagc
ctcatccaggacgcccgcaacgagcgacagaaggcggaggccgccgccgccgccgctgca
gccgcggagccgggcgaggccctggggggacgggccgggaaggccgcactgaatctcctc
ttcgccctgcgggccaccaagccccccgcgctgtcccgggctgtgaaggtgtttgagaca
tttgaagcccaaatccaccacctggagacccggcccgcccagaagccgcaggcagggggc
ccgcacctggagtactttgtgcgctgtgaggtacccagcgccgccctgcccaccctgctc
agctccctgcgccgcgtggccgaagatgtgcggggcgctggggagaacaaggtcctctgg
ttcccaaggaaagtttctgagctggacaagtgtcaccacctggtcaccaagtttgaccct
gacctggacttggaccatccgggcttctcggaccaggtgtaccgccagcgcaggaagctg
attgctgagattgccttccagtacaagcaaggcgaccctattccccacgtggagtacacg
gccgaggagactgccacctggaaggaggtctacaccacgctgcggggcctctatgccacc
cacgcgtgccgggaacacctggaggctttcgagctgctggagcacttctgcgggtaccgg
gaggacagcatcccccagctggaggacgtctcccgcttcctaaaggagcggacgggcttc
cagctgcggcccgtggccggcctgctgtccgcccgggacttcctggccagcctggccttc
cgcgtgttccagtgcacccagtacatccgccatgcctcctcccccatgcactcccctgag
ccggactgctgccacgagctgctggggcacgtgcccatgctggccgaccggaccttcgcc
cagttctcccaggacatcggcctcgcatccctgggggcatcggacgaagaaattgagaag
ctgtccacgctgtactggttcacggtggagtttgggctgtgcaaacagaacggcgaggtg
aaggcctacggagcggggctgctgtcctcctatggggagctcctgcattccctgtctgag
gggcccgagatccgggccttcgaccccgatgcagcggccgtgcagccctaccaggaccag
acttatcagcctgtctactttgtgtctgagagcttcagcgatgccaaggacaaactcagg
agctatgcctcccgcatccagcgccccttctccgtgaagtttgacccatacacgctggcc
atcgatgtgctggacagcccccacgccatccgacgcgccctggatggtgtccaggacgag
ctgcacgccctcacccacgccctgagcgccatcagctag

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