Mus caroli (Ryukyu mouse): 110284110 Help Entry 110284110         CDS       T05910                                  Symbol Tnf Name (RefSeq) tumor necrosis factor   KO K03156   tumor necrosis factor superfamily, member 2 Organism mcal  Mus caroli (Ryukyu mouse) Pathway mcal01523   Antifolate resistance mcal04010   MAPK signaling pathway mcal04060   Cytokine-cytokine receptor interaction mcal04061   Viral protein interaction with cytokine and cytokine receptor mcal04064   NF-kappa B signaling pathway mcal04071   Sphingolipid signaling pathway mcal04150   mTOR signaling pathway mcal04210   Apoptosis mcal04217   Necroptosis mcal04350   TGF-beta signaling pathway mcal04380   Osteoclast differentiation mcal04612   Antigen processing and presentation mcal04620   Toll-like receptor signaling pathway mcal04621   NOD-like receptor signaling pathway mcal04622   RIG-I-like receptor signaling pathway mcal04625   C-type lectin receptor signaling pathway mcal04640   Hematopoietic cell lineage mcal04650   Natural killer cell mediated cytotoxicity mcal04657   IL-17 signaling pathway mcal04660   T cell receptor signaling pathway mcal04664   Fc epsilon RI signaling pathway mcal04668   TNF signaling pathway mcal04920   Adipocytokine signaling pathway mcal04930   Type II diabetes mellitus mcal04931   Insulin resistance mcal04932   Non-alcoholic fatty liver disease mcal04933   AGE-RAGE signaling pathway in diabetic complications mcal04936   Alcoholic liver disease mcal04940   Type I diabetes mellitus mcal05010   Alzheimer disease mcal05014   Amyotrophic lateral sclerosis mcal05020   Prion disease mcal05022   Pathways of neurodegeneration - multiple diseases mcal05132   Salmonella infection mcal05133   Pertussis mcal05134   Legionellosis mcal05135   Yersinia infection mcal05140   Leishmaniasis mcal05142   Chagas disease mcal05143   African trypanosomiasis mcal05144   Malaria mcal05145   Toxoplasmosis mcal05146   Amoebiasis mcal05152   Tuberculosis mcal05160   Hepatitis C mcal05161   Hepatitis B mcal05163   Human cytomegalovirus infection mcal05164   Influenza A mcal05165   Human papillomavirus infection mcal05166   Human T-cell leukemia virus 1 infection mcal05168   Herpes simplex virus 1 infection mcal05169   Epstein-Barr virus infection mcal05170   Human immunodeficiency virus 1 infection mcal05171   Coronavirus disease - COVID-19 mcal05205   Proteoglycans in cancer mcal05310   Asthma mcal05321   Inflammatory bowel disease mcal05322   Systemic lupus erythematosus mcal05323   Rheumatoid arthritis mcal05330   Allograft rejection mcal05332   Graft-versus-host disease mcal05410   Hypertrophic cardiomyopathy mcal05414   Dilated cardiomyopathy mcal05417   Lipid and atherosclerosis mcal05418   Fluid shear stress and atherosclerosis Brite KEGG Orthology (KO) [BR:mcal00001]  09130 Environmental Information Processing   09132 Signal transduction    04010 MAPK signaling pathway     110284110 (Tnf)    04350 TGF-beta signaling pathway     110284110 (Tnf)    04064 NF-kappa B signaling pathway     110284110 (Tnf)    04668 TNF signaling pathway     110284110 (Tnf)    04071 Sphingolipid signaling pathway     110284110 (Tnf)    04150 mTOR signaling pathway     110284110 (Tnf)   09133 Signaling molecules and interaction    04060 Cytokine-cytokine receptor interaction     110284110 (Tnf)    04061 Viral protein interaction with cytokine and cytokine receptor     110284110 (Tnf)  09140 Cellular Processes   09143 Cell growth and death    04210 Apoptosis     110284110 (Tnf)    04217 Necroptosis     110284110 (Tnf)  09150 Organismal Systems   09151 Immune system    04640 Hematopoietic cell lineage     110284110 (Tnf)    04620 Toll-like receptor signaling pathway     110284110 (Tnf)    04621 NOD-like receptor signaling pathway     110284110 (Tnf)    04622 RIG-I-like receptor signaling pathway     110284110 (Tnf)    04625 C-type lectin receptor signaling pathway     110284110 (Tnf)    04650 Natural killer cell mediated cytotoxicity     110284110 (Tnf)    04612 Antigen processing and presentation     110284110 (Tnf)    04660 T cell receptor signaling pathway     110284110 (Tnf)    04657 IL-17 signaling pathway     110284110 (Tnf)    04664 Fc epsilon RI signaling pathway     110284110 (Tnf)   09152 Endocrine system    04920 Adipocytokine signaling pathway     110284110 (Tnf)   09158 Development and regeneration    04380 Osteoclast differentiation     110284110 (Tnf)  09160 Human Diseases   09161 Cancer: overview    05205 Proteoglycans in cancer     110284110 (Tnf)   09172 Infectious disease: viral    05166 Human T-cell leukemia virus 1 infection     110284110 (Tnf)    05170 Human immunodeficiency virus 1 infection     110284110 (Tnf)    05161 Hepatitis B     110284110 (Tnf)    05160 Hepatitis C     110284110 (Tnf)    05171 Coronavirus disease - COVID-19     110284110 (Tnf)    05164 Influenza A     110284110 (Tnf)    05168 Herpes simplex virus 1 infection     110284110 (Tnf)    05163 Human cytomegalovirus infection     110284110 (Tnf)    05169 Epstein-Barr virus infection     110284110 (Tnf)    05165 Human papillomavirus infection     110284110 (Tnf)   09171 Infectious disease: bacterial    05132 Salmonella infection     110284110 (Tnf)    05135 Yersinia infection     110284110 (Tnf)    05133 Pertussis     110284110 (Tnf)    05134 Legionellosis     110284110 (Tnf)    05152 Tuberculosis     110284110 (Tnf)   09174 Infectious disease: parasitic    05146 Amoebiasis     110284110 (Tnf)    05144 Malaria     110284110 (Tnf)    05145 Toxoplasmosis     110284110 (Tnf)    05140 Leishmaniasis     110284110 (Tnf)    05142 Chagas disease     110284110 (Tnf)    05143 African trypanosomiasis     110284110 (Tnf)   09163 Immune disease    05310 Asthma     110284110 (Tnf)    05322 Systemic lupus erythematosus     110284110 (Tnf)    05323 Rheumatoid arthritis     110284110 (Tnf)    05321 Inflammatory bowel disease     110284110 (Tnf)    05330 Allograft rejection     110284110 (Tnf)    05332 Graft-versus-host disease     110284110 (Tnf)   09164 Neurodegenerative disease    05010 Alzheimer disease     110284110 (Tnf)    05014 Amyotrophic lateral sclerosis     110284110 (Tnf)    05020 Prion disease     110284110 (Tnf)    05022 Pathways of neurodegeneration - multiple diseases     110284110 (Tnf)   09166 Cardiovascular disease    05417 Lipid and atherosclerosis     110284110 (Tnf)    05418 Fluid shear stress and atherosclerosis     110284110 (Tnf)    05410 Hypertrophic cardiomyopathy     110284110 (Tnf)    05414 Dilated cardiomyopathy     110284110 (Tnf)   09167 Endocrine and metabolic disease    04930 Type II diabetes mellitus     110284110 (Tnf)    04940 Type I diabetes mellitus     110284110 (Tnf)    04936 Alcoholic liver disease     110284110 (Tnf)    04932 Non-alcoholic fatty liver disease     110284110 (Tnf)    04931 Insulin resistance     110284110 (Tnf)    04933 AGE-RAGE signaling pathway in diabetic complications     110284110 (Tnf)   09176 Drug resistance: antineoplastic    01523 Antifolate resistance     110284110 (Tnf)  09180 Brite Hierarchies   09183 Protein families: signaling and cellular processes    04052 Cytokines and neuropeptides [BR:mcal04052]     110284110 (Tnf)    00536 Glycosaminoglycan binding proteins [BR:mcal00536]     110284110 (Tnf) Cytokines and neuropeptides [BR:mcal04052]  Cytokines   Tumor necrosis fators    110284110 (Tnf) Glycosaminoglycan binding proteins [BR:mcal00536]  Heparan sulfate / Heparin   Cytokines    110284110 (Tnf) BRITE hierarchy SSDB OrthologParalogGene clusterGFIT Motif Pfam:  TNF Motif Other DBs NCBI-GeneID:  110284110 NCBI-ProteinID:  XP_021005394 Ensembl:  MGP_CAROLIEiJ_G0021514 UniProt:  A0A6P5NRJ1 LinkDB All DBs Position 17:complement(31941237..31943982) Genome browser AA seq 235 aa AA seqDB search MSTESMIRDVELAEEALPKKMGGFQNSRRCLCLSLFSFLLVAGATTLFCLLNFGVIGPQR DEKFPNGLPLISSMAQTLTLRSSSQNSSDKPVAHVVANHQVKEQLEWLSQRANALLANGM DLKDNQLVVPADGLYLVYSQVLFTGQGCPDYVLLTHTVSRFAIAYQEKVNLLSAIKSPCP KDTPEGAELKPWYEPIYLGGVFQLEKGDQLSAEVNLPEYLDFAESGQVYFGVIAL NT seq 708 nt NT seq  +upstreamnt  +downstreamnt atgagcacagaaagcatgatccgagacgtggaactggcagaagaggcactcccaaaaaag atggggggcttccagaactccaggcggtgcctgtgtctcagcctcttctcattcctgctt gtggcaggggccaccacgctcttctgtctactgaacttcggggtgatcggtccccaaagg gatgagaagttcccaaatggcctccctctcatcagttctatggcccagaccctcacactc agatcatcttctcaaaattcgagtgacaagcctgtagcccacgtcgtagcaaaccaccaa gtgaaggagcagctggagtggctgagccagcgcgccaacgccctcctggccaacggcatg gatctcaaagacaatcaactagtggtgccagccgatgggttgtaccttgtctactcccag gttctcttcacgggacaaggctgccccgactatgtgctcctcacccacaccgtcagccga tttgctatcgcataccaggagaaagtcaacctcctctctgccatcaagagcccctgcccc aaggacacccctgagggggctgagctcaaaccctggtatgagcccatatacctgggagga gtcttccaactggagaagggggaccaactcagcgctgaggtcaatctgcccgagtactta gactttgccgagtctgggcaggtctactttggagtcattgctctgtga

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