Mus caroli (Ryukyu mouse): 110300614 Help Entry 110300614         CDS       T05910                                  Symbol Irs2 Name (RefSeq) insulin receptor substrate 2   KO K07187   insulin receptor substrate 2 Organism mcal  Mus caroli (Ryukyu mouse) Pathway mcal04022   cGMP-PKG signaling pathway mcal04068   FoxO signaling pathway mcal04081   Hormone signaling mcal04140   Autophagy - animal mcal04152   AMPK signaling pathway mcal04211   Longevity regulating pathway mcal04213   Longevity regulating pathway - multiple species mcal04910   Insulin signaling pathway mcal04920   Adipocytokine signaling pathway mcal04923   Regulation of lipolysis in adipocytes mcal04930   Type II diabetes mellitus mcal04931   Insulin resistance mcal04932   Non-alcoholic fatty liver disease mcal04935   Growth hormone synthesis, secretion and action mcal05010   Alzheimer disease mcal05206   MicroRNAs in cancer Brite KEGG Orthology (KO) [BR:mcal00001]  09130 Environmental Information Processing   09132 Signal transduction    04068 FoxO signaling pathway     110300614 (Irs2)    04022 cGMP-PKG signaling pathway     110300614 (Irs2)    04152 AMPK signaling pathway     110300614 (Irs2)   09133 Signaling molecules and interaction    04081 Hormone signaling     110300614 (Irs2)  09140 Cellular Processes   09141 Transport and catabolism    04140 Autophagy - animal     110300614 (Irs2)  09150 Organismal Systems   09152 Endocrine system    04910 Insulin signaling pathway     110300614 (Irs2)    04923 Regulation of lipolysis in adipocytes     110300614 (Irs2)    04920 Adipocytokine signaling pathway     110300614 (Irs2)    04935 Growth hormone synthesis, secretion and action     110300614 (Irs2)   09149 Aging    04211 Longevity regulating pathway     110300614 (Irs2)    04213 Longevity regulating pathway - multiple species     110300614 (Irs2)  09160 Human Diseases   09161 Cancer: overview    05206 MicroRNAs in cancer     110300614 (Irs2)   09164 Neurodegenerative disease    05010 Alzheimer disease     110300614 (Irs2)   09167 Endocrine and metabolic disease    04930 Type II diabetes mellitus     110300614 (Irs2)    04932 Non-alcoholic fatty liver disease     110300614 (Irs2)    04931 Insulin resistance     110300614 (Irs2) BRITE hierarchy SSDB OrthologParalogGene clusterGFIT Motif Pfam:  IRS PH PH_11 MEKK4_N Motif Other DBs NCBI-GeneID:  110300614 NCBI-ProteinID:  XP_021026522 Ensembl:  MGP_CAROLIEiJ_G0030813 UniProt:  A0A6P5Q9L7 LinkDB All DBs Position 8:complement(7418280..7441266) Genome browser AA seq 1324 aa AA seqDB search MASAPLPGPPASAGGDGPNLNNNNNNNNHSVRKCGYLRKQKHGHKRFFVLRGPGTGGDEA SAAGGSPPQPPRLEYYESEKKWRSKAGAPKRVIALDCCLNINKRADAKHKYLIALYTKDE YFAVAAENEQEQEGWYRALTDLVSEGRSGEGGSGTTGGSCSASLPGVLGGSAGAAGCDDN YGLVTPATAVYREVWQVNLKPKGLGQSKNLTGVYRLCLSARTIGFVKLNCEQPSVTLQLM NIRRCGHSDSFFFIEVGRSAVTGPGELWMQADDSVVAQNIHETILEAMKALKELFEFRPR SKSQSSGSSATHPISVPGARRHHHLVNLPPSQTGLVRRSRTDSLAATPPAAKCTSCRVRT ASEGDGGAAGGAGTAGGRPMSVAGSPLSPGPVRAPLSRSHTLSAGCGGRPSKVTLAPAGG ALQHSRSMSMPVAHSPPAATSPGSLSSSSGHGSGSYPLPPGSHPHLPHPLHHPQGQRPSS GSASASGSPSDPGFMSLDEYGSSPGDLRAFSSHRSNTPESIAETPPARDGSGGELYGYMS MDRPLSHCGRPYRRVSGDGAQDLDRGLRKRTYSLTTPARQRQVPQPSSASLDEYTLMRAT FSGSSGRLCPSFPASSPKVAYNPYPEDYGDIEIGSHKSSSSNLGADDGYMPMTPGAALRS GGPNSCKSDDYMPMSPTSVSAPKQILQPRLAAALPPSGAAVPAPPSGVGRTFPVNGGGYK ASSPAESSPEDSGYMRMWCGSKLSMENPDPKLLPNGDYLNMSPSEAGTAGTPPDFSAALR GGSEGLKGIPGHCYSSLPRSYKAPCSCSGDNDQYVLMSSPVGRILEEERLEPQATPGAGT FGAAGGSHTQPHHSAVPSSMRPSAIGGRPEGFLGQRCRAVRPTRLSLEGLQTLPSMQEYP LPTEPKSPGEYINIDFGEAGTRLSPPAPPLLASAASSSSLLSASSPASSLGSGTPGTSSD SRQRSPLSDYMNLDFSSPKSPKPSTRSGDTVGSMDGLLSPEASSPYPPLPPRPSTSPSSL QQPLPPAPGELYRLPPASPATSQGPTVGSSMSSEPGDNGDYTEMAFGVAATPPQPIVAPP KPEGARVASPTSGLKRLSLMDQVSGVEAFLQVSQPPDPHRGAKVIRADPQGGRRRHSSET FSSTTTVTPVSPSFAHNSKRHNSASVENVSLRKSSEGSSTLGGGDEPPTSPGQAQPLVAV PPVPQARPWNPGQPGALIGCPGGSSSPMRRETSVGFQNGLNYIAIDVRGEQGSLAQSQPQ HPQPGDKNSWSRTRSLGGLLGTVGGSGASGVCGGPGTGALPSASTYASIDFLSHHLKEAT VVKE NT seq 3975 nt NT seq  +upstreamnt  +downstreamnt atggctagcgcgcccctgcctgggccccccgcatcggcgggcggggacggcccgaacctc aataacaacaacaacaacaacaaccacagcgtgcgcaagtgcggctacctgcgcaagcag aagcacggccacaagcgctttttcgtgctgcgcggccccggcacgggcggcgacgaggca tccgcggctggggggtcgccgccgcagcctccgcggctggagtactacgagagcgagaag aagtggaggagcaaggcgggcgcgccgaagcgagtgatcgcgctcgactgctgtctgaac atcaacaagcgtgcggacgccaagcacaagtacctgatcgccctctacaccaaggacgag tacttcgctgtagcggcggagaacgagcaggagcaggagggctggtaccgcgcactcacc gacttggtcagcgaaggccgctctggcgaggggggctcgggcaccaccggcggctcttgc agcgcctctctcccgggagtcctgggcggctcagcgggcgccgctggctgcgatgacaac tacgggctcgtgacacccgccacggccgtctaccgcgaggtgtggcaggtgaacctgaaa cctaagggactgggccagagcaagaacctgactggtgtataccgcctatgcctgtctgcg cgcaccatcggcttcgtgaagctcaattgcgaacagccgtcggtgacgctgcagcttatg aacattcgccgctgcggccactcggacagcttcttcttcatcgaggtgggccgttcggcc gtcaccggtcccggggagttgtggatgcaagccgacgactcggtggtggcgcagaacatc catgagaccatcctggaggctatgaaggcactcaaagagctcttcgagttccggcctcgc agcaagagtcagtcgtccgggtcgtcagccacgcatcccatcagcgtgccgggcgcgcgc cgccaccaccacctagtcaacctaccccctagccagaccggcctggtgcgtcgctcgcgc actgacagcctggctgccacccccccagcagccaagtgcacttcgtgccgggttcgtacg gccagcgagggcgacggcggcgcggcaggcggggccgggacggcaggaggcaggccgatg tcggtggcagggagccccctgagtcccgggccggtgcgcgcgccccttagccgctcgcac accctgagcgccggctgcggaggccgcccgagcaaagtgactctggcgccggcaggggga gccctgcaacacagccgctccatgtccatgcccgtggcgcactcgccgcctgcagccacc agccctggcagcctgtcctccagcagtgggcacggctcgggctcctacccgctgcctcct ggctcccacccgcacctgcctcatccactgcatcacccccaaggccagcgtccgtccagc ggtagtgcctccgcctcgggctcccccagcgacccgggtttcatgtcccttgacgagtat ggctccagccctggcgacctgagagccttcagtagccacaggagcaacacacccgagtca atcgcggagaccccgccagccagagatggcagtgggggcgaactctatgggtacatgagc atggatagacccctgagccactgtggccgcccttaccgtagggtctcaggggatggggcc caggacctggatagaggactgaggaagaggacttactccctaaccacgcctgccaggcag cggcaggtacctcagccttcctctgcctctctagatgaatacactctcatgagggccacc ttctctggcagttcaggtcgcctctgcccatccttccctgcgtcctctcccaaagtggcc tacaacccttacccagaggactatggagacattgagattggttctcacaagagttccagc agtaacctgggagcagatgatggctacatgcccatgacccctggggcagcccttaggagt ggtggtcccaatagctgcaagagcgatgactacatgcccatgagccccaccagcgtgtct gctcccaaacagattctgcagccacgcttggcagcggccttgcccccttccggagcagcc gtgccagcacccccttcaggggtgggcaggaccttcccagtaaacggaggtggctacaaa gccagctccccagcggagagctccccagaagatagtgggtacatgcgaatgtggtgtggc tccaagctgtctatggagaacccagaccctaagctactccccaacggggactacctcaac atgtcccccagcgaggcaggcactgcagggaccccacctgacttctcagcagctttgcgt ggaggcagtgaaggcctcaaaggcatccccggccactgctacagctctttgccccgctct tataaggctccctgttcctgcagcggagacaatgaccagtatgtgctcatgagctcccct gtgggccggatcttggaagaggagagactggagccccaggccaccccaggggctggcacc tttggggcagctggtggtagtcatacccagcctcatcactcagcagtgccttcctccatg aggccgagtgccatcggtggccgccctgagggcttcctgggccagcgctgtcgggcagtg cggcccacacgcctatcactagagggactgcagacccttcccagcatgcaagagtaccct ctacccacagagcccaagagccctggcgagtatatcaacattgactttggtgaggcaggt acccgtctgtctccgcctgcccccccactactggcatccgcagcctcatcttcttcactg ctctcagccagtagtcctgcttcatccctgggttcaggtaccccaggcaccagcagcgac agccggcagcgctctccactctctgactatatgaacctggacttcagttctcccaagtcc cctaagcctagcacccgcagtggggacacagtaggctccatggatggccttctctctcca gaggcttcatccccatacccaccactgcctccacgtccttccacttccccttcctcctta cagcagcctctgccacctgccccgggagaactataccgcctgcctccagcatcacctgcc acttcccagggtcccactgttggctcctcaatgtcctctgagcctggggataatggtgac tataccgagatggcctttggtgtggctgcaaccccgcctcaacctatcgtggcaccccca aagccagaaggtgcccgagtggccagtcccacttcgggcttgaagcggctaagtctcatg gatcaggtatccggggtggaggccttccttcaagtcagccagccccctgacccccaccgg ggtgctaaggtcatccgtgcagacccacaggggggacgtcgtcgccacagttcagagacc ttttcctctaccaccaccgtcaccccagtgtccccatcctttgcccacaattccaagcgc cacaattcggcctctgtggaaaatgtctcactcaggaaaagcagtgaaggcagcagcacc ctgggaggaggtgatgagccacccacatccccaggacaggcacagcccttggtggctgtg cccccagtgccacaggctaggccgtggaatccaggtcagcccggagctttgattggctgt cctggaggcagcagttctcccatgcgcagagagacctccgtgggtttccagaacggcctc aactatatcgccatcgatgtgagaggtgagcaggggtccttggcgcagtctcagccgcag catccgcagccaggagacaagaactcctggagccggacccgtagccttggggggctcctc ggcaccgtcggaggctctggcgccagcggagtgtgtgggggtccaggcactggagctttg ccctctgccagcacctatgcaagcatcgacttcctgtcccatcacttgaaggaagccaca gtcgtgaaagagtga

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