Mus caroli (Ryukyu mouse): 110309477
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Entry
110309477 CDS
T05910
Symbol
Itch
Name
(RefSeq) E3 ubiquitin-protein ligase Itchy homolog
KO
K05632
E3 ubiquitin-protein ligase Itchy [EC:
2.3.2.26
]
Organism
mcal
Mus caroli (Ryukyu mouse)
Pathway
mcal04120
Ubiquitin mediated proteolysis
mcal04144
Endocytosis
mcal04330
Notch signaling pathway
mcal04668
TNF signaling pathway
mcal04932
Non-alcoholic fatty liver disease
Brite
KEGG Orthology (KO) [BR:
mcal00001
]
09120 Genetic Information Processing
09123 Folding, sorting and degradation
04120 Ubiquitin mediated proteolysis
110309477 (Itch)
09130 Environmental Information Processing
09132 Signal transduction
04330 Notch signaling pathway
110309477 (Itch)
04668 TNF signaling pathway
110309477 (Itch)
09140 Cellular Processes
09141 Transport and catabolism
04144 Endocytosis
110309477 (Itch)
09160 Human Diseases
09167 Endocrine and metabolic disease
04932 Non-alcoholic fatty liver disease
110309477 (Itch)
09180 Brite Hierarchies
09182 Protein families: genetic information processing
04131 Membrane trafficking [BR:
mcal04131
]
110309477 (Itch)
04121 Ubiquitin system [BR:
mcal04121
]
110309477 (Itch)
Enzymes [BR:
mcal01000
]
2. Transferases
2.3 Acyltransferases
2.3.2 Aminoacyltransferases
2.3.2.26 HECT-type E3 ubiquitin transferase
110309477 (Itch)
Membrane trafficking [BR:
mcal04131
]
Endocytosis
Clathrin-mediated endocytosis
Ubiquitin E3 ligases
110309477 (Itch)
Ubiquitin system [BR:
mcal04121
]
Ubiquitin ligases (E3)
HECT type E3
110309477 (Itch)
BRITE hierarchy
SSDB
Ortholog
Paralog
Gene cluster
GFIT
Motif
Pfam:
HECT
WW
C2
YejG
Motif
Other DBs
NCBI-GeneID:
110309477
NCBI-ProteinID:
XP_021037821
Ensembl:
MGP_CAROLIEiJ_G0024523
UniProt:
A0A6P5QTS8
LinkDB
All DBs
Position
2:147052533..147176205
Genome browser
AA seq
864 aa
AA seq
DB search
MSDSGPQLDSMGSLTMKSQLQITVISAKLKENKKNWFGPSPYVEVTVDGQSKKTEKCNNT
NSPKWKQPLTVIVTPTSKLCFRVWSHQTLKSDVLLGTAGLDIYETLKSNNMKLEEVVMTL
QLVGDKEPTEMMGDLSVCLDGLQVEAEVVTNGETPCSESTTQNDDGCRPRDDTRVSTNGS
EDPEVAASGENKRANGNNSPSLSNGGFKPSRPPRPSRPPPPTPRRPASVNGSPSTNSDSD
GSSTGSLPPTNTNVNTSTSEGATSGLIIPLTISGGSGPRPLNTVSQAPLPPGWEQRVDQH
GRVYYVDHVEKRTTWDRPEPLPPGWERRVDNMGRIYYVDHFTRTTTWQRPTLESVRNYEQ
WQLQRSQLQGAMQQFNQRFIYGNQDLFATSQNKEFDPLGPLPPGWEKRTDSNGRVYFVNH
NTRITQWEDPRSQGQLNEKPLPEGWEMRFTVDGIPYFVDHNRRATTYIDPRTGKSALDNG
PQIAYVRDFKAKVQYFRFWCQQLAMPQHIKITVTRKTLFEDSFQQIMSFSPQDLRRRLWV
IFPGEEGLDYGGVAREWFFLLSHEVLNPMYCLFEYAGKDNYCLQINPASYINPDHLKYFR
FIGRFIAMALFHGKFIDTGFSLPFYKRILNKPVGLKDLESIDPEFYNSLIWVKENNIEEC
GLEMYFSVDKEILGEIKSHDLKPNGGNILVTEENKEEYIRMVAEWRLSRGVEEQTQAFFE
GFNEILPQQYLQYFDAKELEVLLCGMQEIDLNDWQRHAIYRHYTRTSKQIMWFWQFVKEI
DNEKRMRLLQFVTGTCRLPVGGFADLMGSNGPQKFCIEKVGKENWLPRSHTCFNRLDLPP
YKSYEQLKEKLLFAIEETEGFGQE
NT seq
2595 nt
NT seq
+upstream
nt +downstream
nt
atgtctgacagtggaccacagcttgattccatgggtagtctgaccatgaaatctcaactt
cagatcactgtcatctcagccaaacttaaagaaaataaaaagaattggtttggaccaagt
ccttatgtagaagtcacagtagatgggcagtcaaagaagacagaaaaatgcaataataca
aacagtcccaagtggaagcagcccctcacagttattgttacccctacgagtaaattatgt
tttcgtgtgtggagtcaccagaccctgaaatctgatgttttattgggaactgctggatta
gatatttatgaaacattaaagtcaaacaatatgaaacttgaagaagtagttatgactttg
cagcttgtaggtgacaaagagccaacagagatgatgggagatttgtcagtttgtcttgat
gggctgcaagtagaagctgaggttgttactaacggtgaaacgccatgctcagagagtact
acacagaatgatgatggctgcagacccagagatgatacaagagtgagcacaaatggatca
gaggaccctgaggttgcagcatcaggggaaaacaagagggccaatgggaacaattctccg
tccctttcaaatggtggttttaagccttctagacctcctagaccttccagaccacctcca
cctaccccacgaagaccagcttctgtcaatggctcaccatccacgaattctgacagtgat
ggatctagtacaggctccttgccaccaacaaatacaaatgtaaatacaagtacatctgaa
ggagcaacatctggattaataattcctcttactatatctggaggctcgggccctaggccc
ctgaatactgtaagccaagctcccctaccacctgggtgggagcagagagtagaccagcat
gggcgtgtttactatgtagaccatgttgaaaagcgaacaacatgggatagaccagaacct
ctacctcctggctgggaacggcgtgtggacaatatgggacgtatttattatgttgaccat
ttcacaagaaccacaacatggcagaggccaaccttggaatctgtccggaactatgaacaa
tggcagctacagcgtagtcagcttcagggagcaatgcagcagtttaaccagagattcatc
tatgggaatcaagatttgtttgctacatcacaaaacaaagaatttgatccgcttggtccg
ttgccccctggatgggagaagagaactgatagcaacggcagagtgtattttgtcaaccat
aacacccggattactcagtgggaagaccccagaagccaaggtcagttaaatgaaaagccc
ttaccagaaggctgggaaatgagattcacagtggatggaattccgtattttgtggaccac
aatagaagagcaactacttatatagatccacgaacaggaaaatcagccttagacaatggg
ccccaaatagcctatgtgcgggacttcaaggcaaaagttcagtatttccggttctggtgc
cagcaactggccatgccacagcatataaagatcacagtgacaagaaaaacattgtttgag
gattcctttcagcagatcatgagcttcagcccgcaagatctgagaagacgtctgtgggtg
atcttcccaggagaagaaggcttagactatggaggtgtagccagagaatggttctttctt
ttgtcacatgaagtgttgaacccaatgtattgcctgtttgaatatgcagggaaggataac
tactgcctgcagataaaccccgcttcttacatcaatccagaccacctgaaatactttcgt
tttattggcagatttattgccatggctctgtttcatgggaaattcatagatactggattt
tctttaccattctataaacgtatcctgaataaaccagttggacttaaggatttagaatct
attgatccagaattttataattcgctcatctgggttaaagaaaacaatatcgaagaatgt
ggtttggaaatgtacttctcagttgataaagaaattctaggtgaaattaagagtcatgat
ttgaaacccaatggtggtaatattcttgtgacagaagaaaacaaggaggaatacatcagg
atggtagctgagtggaggttgtctcgaggtgttgaagaacagacacaagctttctttgag
ggctttaatgaaattcttcctcagcaatatttgcaatattttgatgcgaaggaattagag
gttcttttgtgtgggatgcaagagattgatttgaatgactggcagagacatgccatctac
cgtcactacaccagaacaagcaagcagatcatgtggttttggcagtttgttaaagaaatt
gataacgagaagaggatgagactcctgcagtttgtcactgggacctgccgactgccagtg
ggcggatttgcggacctcatggggagtaatggaccacagaagttctgcatcgaaaaagtt
ggcaaagaaaattggttacccagaagccatacttgttttaaccgcctggacctcccacct
tacaagagctatgagcagctgaaggaaaagctgttatttgccattgaagaaactgaagga
tttggacaagagtaa
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