Mus caroli (Ryukyu mouse): 110311491
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Entry
110311491 CDS
T05910
Symbol
Bace2
Name
(RefSeq) beta-secretase 2
KO
K07747
beta-site APP-cleaving enzyme 2 (memapsin 1) [EC:
3.4.23.45
]
Organism
mcal
Mus caroli (Ryukyu mouse)
Pathway
mcal05010
Alzheimer disease
Brite
KEGG Orthology (KO) [BR:
mcal00001
]
09160 Human Diseases
09164 Neurodegenerative disease
05010 Alzheimer disease
110311491 (Bace2)
09180 Brite Hierarchies
09181 Protein families: metabolism
01002 Peptidases and inhibitors [BR:
mcal01002
]
110311491 (Bace2)
Enzymes [BR:
mcal01000
]
3. Hydrolases
3.4 Acting on peptide bonds (peptidases)
3.4.23 Aspartic endopeptidases
3.4.23.45 memapsin 1
110311491 (Bace2)
Peptidases and inhibitors [BR:
mcal01002
]
Aspartic peptidases
Family A1: pepsin family
110311491 (Bace2)
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Motif
Pfam:
Asp
TAXi_C
TAXi_N
Motif
Other DBs
NCBI-GeneID:
110311491
NCBI-ProteinID:
XP_021040482
Ensembl:
MGP_CAROLIEiJ_G0021008
UniProt:
A0A6P5R6B0
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All DBs
Position
16:91953711..92040041
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AA seq
514 aa
AA seq
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MGALLRALLLPLLAQWLLSAVPALAPAPFTLPLQVAGAMNHRASAGPGLGTPELPRADGL
ALALEPVRATANFLAMVDNLQGDSGRGYYLEMLIGTPPQKVQILVDTGSSNFAVAGAPHS
YIDTYFDSESSSTYHSKGFDVTVKYTQGSWTGFVGEDLVTIPKGFNSSFLVNIATIFESE
NFFLPGIKWNGILGLAYAALAKPSSSLETFFDSLVAQAKIPDIFSMQMCGAGLPVAGSGT
NGGSLVLGGIEPSLYKGDIWYTPIKEEWYYQIEILKLEIGGQNLNLDCREYNADKAIVDS
GTTLLRLPQKVFDAVVEAVARTSLIPEFSDGFWTGAQLACWTNSETPWAYFPKISIYLRD
ENASRSFRITILPQLYIQPMMGAGFNYECYRFGISSSTNALVIGATVMEGFYVVFDRAQR
RVGFAVSPCAEIEGTTVSEISGPFSTEDIASNCVPAQALNEPILWIVSYALMSVCGAILL
VLILLLLLPLHCRHAPRDPEVVNDESSLVRHRWK
NT seq
1545 nt
NT seq
+upstream
nt +downstream
nt
atgggcgcgctgcttcgagcactcttgctcccgctgctggcgcagtggctcttgagtgcg
gtccccgcgctggcccccgcgcccttcacgctgcccctccaagtggccggggccatgaac
cacagagcctcggctggtcccggactcgggacccccgagttgccccgggccgatggtctg
gccctcgcactggagcctgtcagggctactgccaacttcttggctatggtggacaacctt
cagggggactctggccgcggctactacctagagatgctgatcgggacccctccgcagaag
gtacagattcttgtggacactggaagcagtaacttcgctgtggcaggtgccccacattcc
tacatagacacctactttgactcagagagctccagcacataccactccaagggctttgat
gtcactgtgaagtacacacaggggagctggactggctttgttggtgaggaccttgtcacc
atcccaaaaggcttcaacagctctttcttggtcaatattgccactatttttgagtctgag
aatttctttttgcctgggattaaatggaatggaatccttggacttgcttatgctgctttg
gccaagccatcaagctctctggaaacgttttttgattccctggtggcccaagcaaagatt
ccggacattttctccatgcagatgtgcggggctggattgccagtagctggttctggtacc
aacggaggtagtcttgtcctgggtgggattgaaccaagtttgtataaaggagatatctgg
tataccccaattaaagaggaatggtactatcaaatagaaatcctgaagttggaaattgga
ggccagaacctcaacctggactgcagagagtataacgcagacaaggccattgtggacagt
ggtaccacgctcctgcgcctgccccagaaggtgtttgatgcagtggtggaagctgtggca
cgcacatctctgattccagagttttctgatggcttctggacaggggcccagctggcatgc
tggacaaattctgaaacgccatgggcatatttccctaagatttctatctacctgagagat
gagaatgccagtcgctccttccggatcaccattctcccacagctctacattcagcccatg
atgggagctggtttcaattatgaatgctaccgttttggtatctcctcttccacaaatgcg
ctggtgattggtgcgaccgtgatggaaggcttctacgtggtctttgacagagctcagagg
agggtgggctttgcagtgagtccctgtgcagagattgaaggtaccacagtgtctgaaatt
tctgggcccttttccacagaagacatagccagcaactgtgttccagcacaggctctgaat
gagcccatcttgtggattgtgtcctatgccctaatgagtgtgtgtggagccattctcctg
gttctgatcctcctcctactgctcccgctgcactgccgtcatgccccccgagaccctgag
gtagttaacgatgagtcctcactagtcagacatcgctggaaatga
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