KEGG   Macaca fascicularis (crab-eating macaque): 102142023
Entry
102142023         CDS       T02918                                 
Symbol
HSD17B5
Name
(RefSeq) aldo-keto reductase family 1 member C3
  KO
K04119  aldo-keto reductase family 1 member C3 [EC:1.1.1.51 1.1.1.188 1.1.1.213 1.1.1.357]
Organism
mcf  Macaca fascicularis (crab-eating macaque)
Pathway
mcf00140  Steroid hormone biosynthesis
mcf00590  Arachidonic acid metabolism
mcf00790  Folate biosynthesis
mcf01100  Metabolic pathways
mcf04913  Ovarian steroidogenesis
mcf05208  Chemical carcinogenesis - reactive oxygen species
Module
mcf_M00976  C19-Steroid hormone biosynthesis, pregnenolone => testosterone => dihydrotestosterone
mcf_M00977  C19-Steroid hormone biosynthesis (androgen backdoor pathway), pregnenolone => androsterone => dihydrotestosterone
Brite
KEGG Orthology (KO) [BR:mcf00001]
 09100 Metabolism
  09103 Lipid metabolism
   00140 Steroid hormone biosynthesis
    102142023 (HSD17B5)
   00590 Arachidonic acid metabolism
    102142023 (HSD17B5)
  09108 Metabolism of cofactors and vitamins
   00790 Folate biosynthesis
    102142023 (HSD17B5)
 09150 Organismal Systems
  09152 Endocrine system
   04913 Ovarian steroidogenesis
    102142023 (HSD17B5)
 09160 Human Diseases
  09161 Cancer: overview
   05208 Chemical carcinogenesis - reactive oxygen species
    102142023 (HSD17B5)
Enzymes [BR:mcf01000]
 1. Oxidoreductases
  1.1  Acting on the CH-OH group of donors
   1.1.1  With NAD+ or NADP+ as acceptor
    1.1.1.51  3(or 17)beta-hydroxysteroid dehydrogenase
     102142023 (HSD17B5)
    1.1.1.188  prostaglandin-F synthase
     102142023 (HSD17B5)
    1.1.1.213  3alpha-hydroxysteroid 3-dehydrogenase (Re-specific)
     102142023 (HSD17B5)
    1.1.1.357  3alpha-hydroxysteroid 3-dehydrogenase
     102142023 (HSD17B5)
SSDB
Motif
Pfam: Aldo_ket_red
Other DBs
NCBI-GeneID: 102142023
NCBI-ProteinID: XP_045255420
Ensembl: ENSMFAG00000034543
LinkDB
Position
9:join(6001341..6001424,6003222..6003389,6004235..6004351,6005613..6005690,6006135..6006257,6008909..6009018,6009289..6009454,6012653..6012735,6014521..6014563)
AA seq 323 aa
MDSKHQRVKLNDGHFMPVLGFGTYAPPEVPRSKALEVTKLAIEAGFRHIDSAHLYNNEEQ
VGLAIRSKIADGTVKREDIFYTSKLWSTFHRPELVRPALENSLKKAQLDYVDLYLIHSPV
SLKPGEELSPTDENGKLIFDIVDLCTTWEAMEKCKDAGLAKSIGVSNFNHRQLEMILNKP
GLKYKPVCNQVECHPYFNQSKLLDFCKSKDTVLVAYSALGSQRDKRWVDQNSPVLLEDPV
LCALAKKHKRTPALIALRYQLQRGVVVLAKSYNEQRIRENVQVFEFQLTSEDMKAIDGLN
RNLRYFNSDSLASHPNYPYSDEY
NT seq 972 nt   +upstreamnt  +downstreamnt
atggattccaaacaccagcgtgtgaagctaaatgatggccacttcatgcctgtattggga
tttggcacctatgcacctccagaggttcccagaagtaaagctttagaggtcacaaaattg
gcaatagaagctgggttccgccatatagattctgctcatttgtacaataatgaggagcag
gttggactggccatccgaagcaagattgcagatggtactgtgaagagagaagacatattc
tacacttcaaagctttggtccacttttcatcgaccagagttggtccgaccagccttggaa
aactcgctgaaaaaagctcaattggactatgttgacctctatctcattcattctccagtg
tctctaaagccaggtgaggaactttcaccaacagatgaaaatggaaaactaatatttgac
atagtggatctctgtaccacttgggaggccatggagaagtgtaaggatgcaggtttggcc
aagtccatcggggtgtcaaacttcaaccacaggcaactggagatgatcctcaacaagcca
ggactcaagtacaagcccgtctgcaaccaggtagaatgtcatccgtatttcaaccagagt
aaattgctagatttctgcaagtcaaaagatactgttctggttgcctatagtgctctggga
tctcagcgagacaaacgatgggtggaccagaactccccggttctcttggaggacccagtc
ctttgtgccttggcaaaaaagcacaagcgaaccccagccctgattgccctgcgctaccag
ctgcagcgtggggttgtggtcctggccaagagctacaatgagcagcggatcagagagaac
gtgcaggtttttgaattccagttgacttcagaggacatgaaagccatagatggcctaaac
agaaatctccgatattttaacagtgatagtctcgctagccaccctaattatccatattca
gatgaatattaa

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