KEGG   Myotis daubentonii (Daubenton's bat): 132241615
Entry
132241615         CDS       T10294                                 
Symbol
TH
Name
(RefSeq) tyrosine 3-monooxygenase
  KO
K00501  tyrosine 3-monooxygenase [EC:1.14.16.2]
Organism
mdt  Myotis daubentonii (Daubenton's bat)
Pathway
mdt00350  Tyrosine metabolism
mdt00790  Folate biosynthesis
mdt01100  Metabolic pathways
mdt04728  Dopaminergic synapse
mdt04917  Prolactin signaling pathway
mdt05012  Parkinson disease
mdt05030  Cocaine addiction
mdt05031  Amphetamine addiction
mdt05034  Alcoholism
Module
mdt_M00042  Catecholamine biosynthesis, tyrosine => dopamine => noradrenaline => adrenaline
Brite
KEGG Orthology (KO) [BR:mdt00001]
 09100 Metabolism
  09105 Amino acid metabolism
   00350 Tyrosine metabolism
    132241615 (TH)
  09108 Metabolism of cofactors and vitamins
   00790 Folate biosynthesis
    132241615 (TH)
 09150 Organismal Systems
  09152 Endocrine system
   04917 Prolactin signaling pathway
    132241615 (TH)
  09156 Nervous system
   04728 Dopaminergic synapse
    132241615 (TH)
 09160 Human Diseases
  09164 Neurodegenerative disease
   05012 Parkinson disease
    132241615 (TH)
  09165 Substance dependence
   05030 Cocaine addiction
    132241615 (TH)
   05031 Amphetamine addiction
    132241615 (TH)
   05034 Alcoholism
    132241615 (TH)
Enzymes [BR:mdt01000]
 1. Oxidoreductases
  1.14  Acting on paired donors, with incorporation or reduction of molecular oxygen
   1.14.16  With reduced pteridine as one donor, and incorporation of one atom of oxygen into the other donor
    1.14.16.2  tyrosine 3-monooxygenase
     132241615 (TH)
SSDB
Motif
Pfam: Biopterin_H TH_ACT TOH_N LTP_2
Other DBs
NCBI-GeneID: 132241615
NCBI-ProteinID: XP_059566549
LinkDB
Position
9:86176595..86183779
AA seq 493 aa
MPTPSATAPQAKAFRRAVSELDAKQAEAIMSPRFIGRRQSLIEDARKEREKAAAAAAAEP
GEPLGAGACVERDGKALLSLLFTLRGAKAAPLSRALKAFETFEAQILHLETRPAQRPRGG
APQLEYFVRCEVPSADLPHLLSSVRRVAEDVRGPGESRVLWFPRKVSELDKCHHLVTKFD
PDLDQDHPGFSDQEYRQRRRLIAEIAFQYRHGDPIPRVEYTAEEIATWKAVYTTLKGLYA
THACREHLEAFELLERFCGYQEDSIPQLEAVSRFLKERTGFQLRPVAGLLSARDFLASLA
FRVFQCTQYIRHASSPMHSPEPDCCHELLGHVPMLADRTFAQFSQDIGLASLGASDEEIE
KLSTLYWFTVEFGLCKQNGEVKAYGAGLLSSYGELLHALSEEPEIRAFDPDAAALQPYQD
QTYQSVYFVSESFSDAKDKLRSYAARIQRPFSVKFDPYTQAIDVLDSPRAVRSSLEGIRD
EMHALTHALSAIS
NT seq 1482 nt   +upstreamnt  +downstreamnt
atgcccacgcccagcgccaccgcgccccaggccaaggccttccgccgggccgtctccgag
ctggacgccaagcaggccgaggccatcatgtcaccgcgcttcatcggacggaggcagagc
ctcatcgaggacgcacgcaaggagagggagaaggcggcggcggcggcggccgcggagccc
ggggagccgttgggggcgggcgcctgcgtggagagagacgggaaggcactgctcagcctg
ctcttcaccctgcgaggggccaaggccgccccgctctcccgcgccctgaaggcctttgag
accttcgaggcccagatcctgcacctggagacgcggccagcgcagcggccgcgggggggc
gccccccaactggagtacttcgtgcgctgcgaggtgcccagcgccgacctgccccacctg
ctcagctccgtgcgccgggtggcggaggacgtgcgcggccccggggagagcagagtcctg
tggttcccgaggaaagtgtctgagctggacaagtgccaccacctggtcaccaagtttgac
cctgacctggaccaggaccacccgggcttctcggaccaggagtaccgccagcgccggagg
ctgatcgccgagatagccttccagtaccgccacggcgaccccattccccgtgtggagtac
acggcggaggagattgccacctggaaggcggtgtacaccaccctcaagggcctgtacgcc
acgcacgcctgccgggagcacctggaggccttcgagctgctggagcgcttctgtgggtac
caggaggacagcatcccccagctggaggccgtctcccgcttcctcaaggagcggaccggc
ttccagctgcggccagtggccggcctgctgtccgcccgggacttcctggccagcctggcc
ttccgtgtgttccagtgcacccagtacatccggcacgcgtcctcgcccatgcactcgccc
gagccggactgctgccatgagctgctggggcacgtgcccatgctggccgaccggaccttt
gcccagttctcccaggacatcggcctggcgtccttgggcgcttcggacgaggagatcgag
aagctgtccacgctgtactggttcacggtggagttcgggctgtgcaagcagaacggagag
gtgaaggcgtacggcgctgggctgctgtcgtcctacggggagctcctgcacgccctgtcc
gaggagcctgagatccgggcctttgaccccgacgcggccgccctgcagccctaccaggac
cagacctaccagtcggtctacttcgtgtcggagagtttcagcgacgccaaggacaagctc
aggagctatgccgcccgcatccagcgtcccttctccgtgaagtttgacccgtacacgcag
gccatcgacgtgctggacagcccccgggccgtccggagctccctggagggcatccgggac
gagatgcacgccctcacccacgcgctcagtgccatcagctaa

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