Micromonospora sp. L5: ML5_4403
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Entry
ML5_4403 CDS
T01379
Name
(GenBank) Beta-ketoacyl synthase
KO
K05552
minimal PKS chain-length factor (CLF/KS beta) [EC:2.3.1.-
2.3.1.260
2.3.1.235
]
Organism
mil
Micromonospora sp. L5
Pathway
mil00253
Tetracycline biosynthesis
mil01056
Biosynthesis of type II polyketide backbone
mil01100
Metabolic pathways
mil01110
Biosynthesis of secondary metabolites
Module
mil_M00778
Type II polyketide backbone biosynthesis, acyl-CoA + malonyl-CoA => polyketide
Brite
KEGG Orthology (KO) [BR:
mil00001
]
09100 Metabolism
09109 Metabolism of terpenoids and polyketides
01056 Biosynthesis of type II polyketide backbone
ML5_4403
00253 Tetracycline biosynthesis
ML5_4403
09180 Brite Hierarchies
09181 Protein families: metabolism
01004 Lipid biosynthesis proteins [BR:
mil01004
]
ML5_4403
01008 Polyketide biosynthesis proteins [BR:
mil01008
]
ML5_4403
Enzymes [BR:
mil01000
]
2. Transferases
2.3 Acyltransferases
2.3.1 Transferring groups other than aminoacyl groups
2.3.1.235 tetracenomycin F2 synthase
ML5_4403
2.3.1.260 tetracycline polyketide synthase
ML5_4403
Lipid biosynthesis proteins [BR:
mil01004
]
Polyketide synthase
Component type
ML5_4403
Polyketide biosynthesis proteins [BR:
mil01008
]
Polyketide synthase (PKS)
Type II PKS
C7-C14 cyclized polyketide type
Octaketide PKS
ML5_4403
Nonaketide PKS
ML5_4403
Decaketide PKS
ML5_4403
BRITE hierarchy
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Ortholog
Paralog
Gene cluster
GFIT
Motif
Pfam:
ketoacyl-synt
Ketoacyl-synt_C
Motif
Other DBs
NCBI-ProteinID:
ADU09880
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All DBs
Position
4680288..4681487
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AA seq
399 aa
AA seq
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MSTAVVTGLGVVAPNGVGAGDYWAATLRGRSAIGRIDLFDVEDYPSRLGGVVTGFDAGNH
LPSRLLPQTDRMTRFALAAADWAVADAGIDRSALAATDLGVSTASASGGFAFGQKELEHL
CADGPSHVSVYQSFAWFYAVNSGQISIRHDMRGPIGVLVADQAGGLDAIAHARRSVRKGA
PLVLTGGMDSALSPYGLAALISSGMLSTADDPHHAYLPFDRRANGHVPGEGGAILTVEDG
DCARERGAHVYGEIAGYAATFDPSPGSGRPGNLGRAVRAALADAGIGPDEVGVVFADAAG
DADADRAEAEVIVDLFGPRGVPVTAPKTMTGRLYSGAGPLDVATALLALRDKVIPPTVNV
VADYALDLVEAPRQLTASVALVLARGRQGFNSALVVRAP
NT seq
1200 nt
NT seq
+upstream
nt +downstream
nt
atgagcaccgccgtggtgacagggctcggcgtcgtcgcgcccaacggcgtcggtgccggg
gactactgggcggcgaccctgcggggccgcagcgcgatcgggagaatcgacctgttcgac
gtcgaggactacccgagccgcctcggcggcgtggtcaccggcttcgacgccgggaaccac
ctgcccagccggctgctgccgcagaccgatcgcatgaccaggttcgcgctggccgccgcg
gactgggcggtcgccgacgccggcatcgaccggtcggcgctggccgcgaccgacctcggc
gtgtcgaccgcgagcgcgtcgggcggattcgcgttcggacagaaggagctcgagcacctg
tgcgccgacggaccgagccacgtcagcgtctaccagtcgtttgcctggttctacgccgtc
aactccggccagatctcgatccggcacgacatgcgcggcccgatcggtgtactcgtcgcc
gaccaggccggtggtctcgacgccatcgcgcacgcccgccgctccgtccgaaagggcgcg
ccgctcgtgctcaccggcgggatggactccgcgctgtccccgtacgggctggccgcgctg
atctccagcggcatgctgtccaccgccgacgacccgcaccatgcctaccttcccttcgac
cgcagggcgaacggccacgtgcccggcgagggcggcgccatcctcaccgtcgaggacggc
gactgtgcccgcgagcgtggtgcccacgtctacggcgagatcgccgggtacgccgccacg
ttcgatccctcaccgggctcgggtcgtccgggcaacctcgggcgtgccgtgcgggcggcc
ctcgccgacgccgggatcggcccggacgaggtcggcgtggtcttcgccgacgcagccggc
gacgcggacgccgaccgggcggaggccgaggtgatcgtcgacctcttcggcccgcgtggc
gtcccggtcaccgcgcccaagacgatgaccggtcgcctgtactccggcgccggcccgctc
gacgtggcgaccgcgctgctcgcgctgcgcgacaaggtcatcccgccgaccgtgaacgtc
gtcgcggactacgccctcgacctggtcgaggccccccggcagctgacggcgtcggttgcc
ctggtgctggcccgcggccggcagggcttcaacagcgcactggttgtacgtgccccatga
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