KEGG   Manis javanica (Malayan pangolin): 108389793
Entry
108389793         CDS       T06054                                 
Symbol
CASP3
Name
(RefSeq) caspase-3
  KO
K02187  caspase 3 [EC:3.4.22.56]
Organism
mjv  Manis javanica (Malayan pangolin)
Pathway
mjv01524  Platinum drug resistance
mjv04010  MAPK signaling pathway
mjv04115  p53 signaling pathway
mjv04148  Efferocytosis
mjv04210  Apoptosis
mjv04215  Apoptosis - multiple species
mjv04623  Cytosolic DNA-sensing pathway
mjv04650  Natural killer cell mediated cytotoxicity
mjv04657  IL-17 signaling pathway
mjv04668  TNF signaling pathway
mjv04726  Serotonergic synapse
mjv04932  Non-alcoholic fatty liver disease
mjv04933  AGE-RAGE signaling pathway in diabetic complications
mjv04936  Alcoholic liver disease
mjv05010  Alzheimer disease
mjv05012  Parkinson disease
mjv05014  Amyotrophic lateral sclerosis
mjv05016  Huntington disease
mjv05020  Prion disease
mjv05022  Pathways of neurodegeneration - multiple diseases
mjv05132  Salmonella infection
mjv05133  Pertussis
mjv05134  Legionellosis
mjv05145  Toxoplasmosis
mjv05146  Amoebiasis
mjv05152  Tuberculosis
mjv05160  Hepatitis C
mjv05161  Hepatitis B
mjv05162  Measles
mjv05163  Human cytomegalovirus infection
mjv05164  Influenza A
mjv05165  Human papillomavirus infection
mjv05167  Kaposi sarcoma-associated herpesvirus infection
mjv05168  Herpes simplex virus 1 infection
mjv05169  Epstein-Barr virus infection
mjv05170  Human immunodeficiency virus 1 infection
mjv05200  Pathways in cancer
mjv05203  Viral carcinogenesis
mjv05205  Proteoglycans in cancer
mjv05206  MicroRNAs in cancer
mjv05210  Colorectal cancer
mjv05222  Small cell lung cancer
mjv05416  Viral myocarditis
mjv05417  Lipid and atherosclerosis
Brite
KEGG Orthology (KO) [BR:mjv00001]
 09130 Environmental Information Processing
  09132 Signal transduction
   04010 MAPK signaling pathway
    108389793 (CASP3)
   04668 TNF signaling pathway
    108389793 (CASP3)
 09140 Cellular Processes
  09141 Transport and catabolism
   04148 Efferocytosis
    108389793 (CASP3)
  09143 Cell growth and death
   04210 Apoptosis
    108389793 (CASP3)
   04215 Apoptosis - multiple species
    108389793 (CASP3)
   04115 p53 signaling pathway
    108389793 (CASP3)
 09150 Organismal Systems
  09151 Immune system
   04623 Cytosolic DNA-sensing pathway
    108389793 (CASP3)
   04650 Natural killer cell mediated cytotoxicity
    108389793 (CASP3)
   04657 IL-17 signaling pathway
    108389793 (CASP3)
  09156 Nervous system
   04726 Serotonergic synapse
    108389793 (CASP3)
 09160 Human Diseases
  09161 Cancer: overview
   05200 Pathways in cancer
    108389793 (CASP3)
   05206 MicroRNAs in cancer
    108389793 (CASP3)
   05205 Proteoglycans in cancer
    108389793 (CASP3)
   05203 Viral carcinogenesis
    108389793 (CASP3)
  09162 Cancer: specific types
   05210 Colorectal cancer
    108389793 (CASP3)
   05222 Small cell lung cancer
    108389793 (CASP3)
  09172 Infectious disease: viral
   05170 Human immunodeficiency virus 1 infection
    108389793 (CASP3)
   05161 Hepatitis B
    108389793 (CASP3)
   05160 Hepatitis C
    108389793 (CASP3)
   05164 Influenza A
    108389793 (CASP3)
   05162 Measles
    108389793 (CASP3)
   05168 Herpes simplex virus 1 infection
    108389793 (CASP3)
   05163 Human cytomegalovirus infection
    108389793 (CASP3)
   05167 Kaposi sarcoma-associated herpesvirus infection
    108389793 (CASP3)
   05169 Epstein-Barr virus infection
    108389793 (CASP3)
   05165 Human papillomavirus infection
    108389793 (CASP3)
  09171 Infectious disease: bacterial
   05132 Salmonella infection
    108389793 (CASP3)
   05133 Pertussis
    108389793 (CASP3)
   05134 Legionellosis
    108389793 (CASP3)
   05152 Tuberculosis
    108389793 (CASP3)
  09174 Infectious disease: parasitic
   05146 Amoebiasis
    108389793 (CASP3)
   05145 Toxoplasmosis
    108389793 (CASP3)
  09164 Neurodegenerative disease
   05010 Alzheimer disease
    108389793 (CASP3)
   05012 Parkinson disease
    108389793 (CASP3)
   05014 Amyotrophic lateral sclerosis
    108389793 (CASP3)
   05016 Huntington disease
    108389793 (CASP3)
   05020 Prion disease
    108389793 (CASP3)
   05022 Pathways of neurodegeneration - multiple diseases
    108389793 (CASP3)
  09166 Cardiovascular disease
   05417 Lipid and atherosclerosis
    108389793 (CASP3)
   05416 Viral myocarditis
    108389793 (CASP3)
  09167 Endocrine and metabolic disease
   04936 Alcoholic liver disease
    108389793 (CASP3)
   04932 Non-alcoholic fatty liver disease
    108389793 (CASP3)
   04933 AGE-RAGE signaling pathway in diabetic complications
    108389793 (CASP3)
  09176 Drug resistance: antineoplastic
   01524 Platinum drug resistance
    108389793 (CASP3)
 09180 Brite Hierarchies
  09181 Protein families: metabolism
   01002 Peptidases and inhibitors [BR:mjv01002]
    108389793 (CASP3)
Enzymes [BR:mjv01000]
 3. Hydrolases
  3.4  Acting on peptide bonds (peptidases)
   3.4.22  Cysteine endopeptidases
    3.4.22.56  caspase-3
     108389793 (CASP3)
Peptidases and inhibitors [BR:mjv01002]
 Cysteine peptidases
  Family C14: caspase family
   108389793 (CASP3)
SSDB
Motif
Pfam: Peptidase_C14
Other DBs
NCBI-GeneID: 108389793
NCBI-ProteinID: XP_036852437
LinkDB
Position
Unknown
AA seq 277 aa
METSENSVDSKSIKNSETKIFHGSKSVDSGIFLDSSYKMDYPEMGLCVIINNKNFDESTG
MQSRPGTDVDAADLRETFTNLKYEVRNKNDLTCEQIMELMYSVSKEDHSKRSSFICVLLS
HGDEGVIFGTDGPIDLKKLTRFFRGDCCRSLTGKPKLFIIQACRGTELDSGIETDSSAQD
DMGCQKIPVEADFLYAYSTAPGYYSWRNSRNGSWFIQSLCTMLKQYAHKLEVIHILTRVN
RKVAIEFESYSLDSALHAKKQIPCIVSMLTKELYFYH
NT seq 834 nt   +upstreamnt  +downstreamnt
atggagaccagtgaaaactcagtggattcaaaatccattaaaaattcagaaacaaagatc
tttcatggaagcaagtcagtggactctggaatattcttggacagtagttacaaaatggat
tatcctgaaatgggtttatgtgtaataattaataataagaactttgatgaaagtactgga
atgcagtctcggcctggtacagatgttgatgcagcagacctcagggaaacattcacaaac
ttgaaatatgaagtcaggaataaaaatgatcttacatgcgagcaaattatggaattgatg
tacagtgtttctaaagaagatcatagcaaaaggagcagtttcatttgcgtgctactaagc
catggtgatgaaggagtaatttttggaacagatggacctattgacctgaaaaaattaaca
cgtttcttcagaggggattgttgtagaagtctaactggaaaacccaaacttttcattatt
caggcctgccgaggtacagaactggactctggtattgagactgacagtagtgctcaggat
gacatggggtgtcagaaaataccagttgaggccgacttcttgtatgcatattctacagca
cctggttactattcctggcgaaattcaaggaatggatcctggttcatccagtcactctgt
actatgctcaaacagtacgctcacaaacttgaggttatacacatccttactcgggttaac
cggaaagtagcaatagaatttgagtcttactctcttgattccgctcttcatgcaaagaaa
cagattccatgtattgtgtctatgctcacaaaagaactgtatttttatcactaa

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