Mandrillus leucophaeus (drill): 105553959 Help Entry 105553959         CDS       T08763                                  Symbol CASP3 Name (RefSeq) caspase-3   KO K02187   caspase 3 [EC:3.4.22.56] Organism mleu  Mandrillus leucophaeus (drill) Pathway mleu01524   Platinum drug resistance mleu04010   MAPK signaling pathway mleu04115   p53 signaling pathway mleu04148   Efferocytosis mleu04210   Apoptosis mleu04215   Apoptosis - multiple species mleu04623   Cytosolic DNA-sensing pathway mleu04650   Natural killer cell mediated cytotoxicity mleu04657   IL-17 signaling pathway mleu04668   TNF signaling pathway mleu04726   Serotonergic synapse mleu04932   Non-alcoholic fatty liver disease mleu04933   AGE-RAGE signaling pathway in diabetic complications mleu04936   Alcoholic liver disease mleu05010   Alzheimer disease mleu05012   Parkinson disease mleu05014   Amyotrophic lateral sclerosis mleu05016   Huntington disease mleu05020   Prion disease mleu05022   Pathways of neurodegeneration - multiple diseases mleu05132   Salmonella infection mleu05133   Pertussis mleu05134   Legionellosis mleu05145   Toxoplasmosis mleu05146   Amoebiasis mleu05152   Tuberculosis mleu05160   Hepatitis C mleu05161   Hepatitis B mleu05162   Measles mleu05163   Human cytomegalovirus infection mleu05164   Influenza A mleu05165   Human papillomavirus infection mleu05167   Kaposi sarcoma-associated herpesvirus infection mleu05168   Herpes simplex virus 1 infection mleu05169   Epstein-Barr virus infection mleu05170   Human immunodeficiency virus 1 infection mleu05200   Pathways in cancer mleu05203   Viral carcinogenesis mleu05205   Proteoglycans in cancer mleu05206   MicroRNAs in cancer mleu05210   Colorectal cancer mleu05222   Small cell lung cancer mleu05416   Viral myocarditis mleu05417   Lipid and atherosclerosis Brite KEGG Orthology (KO) [BR:mleu00001]  09130 Environmental Information Processing   09132 Signal transduction    04010 MAPK signaling pathway     105553959 (CASP3)    04668 TNF signaling pathway     105553959 (CASP3)  09140 Cellular Processes   09141 Transport and catabolism    04148 Efferocytosis     105553959 (CASP3)   09143 Cell growth and death    04210 Apoptosis     105553959 (CASP3)    04215 Apoptosis - multiple species     105553959 (CASP3)    04115 p53 signaling pathway     105553959 (CASP3)  09150 Organismal Systems   09151 Immune system    04623 Cytosolic DNA-sensing pathway     105553959 (CASP3)    04650 Natural killer cell mediated cytotoxicity     105553959 (CASP3)    04657 IL-17 signaling pathway     105553959 (CASP3)   09156 Nervous system    04726 Serotonergic synapse     105553959 (CASP3)  09160 Human Diseases   09161 Cancer: overview    05200 Pathways in cancer     105553959 (CASP3)    05206 MicroRNAs in cancer     105553959 (CASP3)    05205 Proteoglycans in cancer     105553959 (CASP3)    05203 Viral carcinogenesis     105553959 (CASP3)   09162 Cancer: specific types    05210 Colorectal cancer     105553959 (CASP3)    05222 Small cell lung cancer     105553959 (CASP3)   09172 Infectious disease: viral    05170 Human immunodeficiency virus 1 infection     105553959 (CASP3)    05161 Hepatitis B     105553959 (CASP3)    05160 Hepatitis C     105553959 (CASP3)    05164 Influenza A     105553959 (CASP3)    05162 Measles     105553959 (CASP3)    05168 Herpes simplex virus 1 infection     105553959 (CASP3)    05163 Human cytomegalovirus infection     105553959 (CASP3)    05167 Kaposi sarcoma-associated herpesvirus infection     105553959 (CASP3)    05169 Epstein-Barr virus infection     105553959 (CASP3)    05165 Human papillomavirus infection     105553959 (CASP3)   09171 Infectious disease: bacterial    05132 Salmonella infection     105553959 (CASP3)    05133 Pertussis     105553959 (CASP3)    05134 Legionellosis     105553959 (CASP3)    05152 Tuberculosis     105553959 (CASP3)   09174 Infectious disease: parasitic    05146 Amoebiasis     105553959 (CASP3)    05145 Toxoplasmosis     105553959 (CASP3)   09164 Neurodegenerative disease    05010 Alzheimer disease     105553959 (CASP3)    05012 Parkinson disease     105553959 (CASP3)    05014 Amyotrophic lateral sclerosis     105553959 (CASP3)    05016 Huntington disease     105553959 (CASP3)    05020 Prion disease     105553959 (CASP3)    05022 Pathways of neurodegeneration - multiple diseases     105553959 (CASP3)   09166 Cardiovascular disease    05417 Lipid and atherosclerosis     105553959 (CASP3)    05416 Viral myocarditis     105553959 (CASP3)   09167 Endocrine and metabolic disease    04936 Alcoholic liver disease     105553959 (CASP3)    04932 Non-alcoholic fatty liver disease     105553959 (CASP3)    04933 AGE-RAGE signaling pathway in diabetic complications     105553959 (CASP3)   09176 Drug resistance: antineoplastic    01524 Platinum drug resistance     105553959 (CASP3)  09180 Brite Hierarchies   09181 Protein families: metabolism    01002 Peptidases and inhibitors [BR:mleu01002]     105553959 (CASP3) Enzymes [BR:mleu01000]  3. Hydrolases   3.4  Acting on peptide bonds (peptidases)    3.4.22  Cysteine endopeptidases     3.4.22.56  caspase-3      105553959 (CASP3) Peptidases and inhibitors [BR:mleu01002]  Cysteine peptidases   Family C14: caspase family    105553959 (CASP3) BRITE hierarchy SSDB OrthologParalogGFIT Motif Pfam:  Peptidase_C14 SICA_beta Motif Other DBs NCBI-GeneID:  105553959 NCBI-ProteinID:  XP_011855548 Ensembl:  ENSMLEG00000028788 UniProt:  A0A2K5Y0W1 LinkDB All DBs Position Unknown AA seq 277 aa AA seqDB search MENSENSVDSKSIKSLESKIIHGSKSVDSGISLDNSYKMDYPEMGLCIIINNKNFHKSTG MASRSGTDVDAANLRETFINLKYEVRNKNDLTREEIVELMRNVSKEDHSKRSSFVCVLLS HGEEGIIFGTNGPLDLKKITSFFRGDCCRSLTGKPKLFIIQACRGTELDCGIETDSGVED DMACHKIPVEADFLYAYSTAPGYYSWRNSKDGSWFIQSLCAMLKQYADKLEFMHILTRVN RKVATEFESFSLDATFHAKKQIPCIVSMLTKELYFYH NT seq 834 nt NT seq  +upstreamnt  +downstreamnt atggagaacagtgaaaactcagtggattcaaaatccattaaaagtttggaatcaaaaatc atacatggaagcaaatcagtggactctggaatatccctggacaacagttataaaatggat tatcctgagatgggtttatgtataataattaataataagaattttcataaaagcactgga atggcatctcggtctggtacagatgttgatgcagcaaacctcagggaaacattcataaac ttgaaatatgaagtcaggaataaaaacgatcttacacgtgaagaaattgtggaattgatg cgtaatgtttctaaagaagatcacagcaaaaggagcagttttgtttgtgtgcttctgagc catggtgaagaaggaataatttttggaacaaatggacctcttgacctgaaaaaaattaca agctttttcagaggggattgttgtagaagtctaactggaaaacccaaacttttcattatt caggcctgccgtggcacagaactggactgtggcattgagacagacagtggtgttgaggat gacatggcgtgtcataaaatcccagtggaggccgacttcttgtatgcatactccacagca cctggttattattcttggcgaaattcaaaggatggctcctggttcatccagtcgctttgt gccatgctgaaacagtacgccgacaagcttgaatttatgcacattcttacccgggttaac cgaaaggtggcaacagaatttgagtccttttcccttgatgctacttttcatgcaaagaaa cagattccatgtattgtttccatgctcacaaaagaactgtatttttatcactaa

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