KEGG   Mirounga leonina (Southern elephant seal): 118010074
Entry
118010074         CDS       T07472                                 
Symbol
CASP3
Name
(RefSeq) caspase-3 isoform X1
  KO
K02187  caspase 3 [EC:3.4.22.56]
Organism
mlx  Mirounga leonina (Southern elephant seal)
Pathway
mlx01524  Platinum drug resistance
mlx04010  MAPK signaling pathway
mlx04115  p53 signaling pathway
mlx04148  Efferocytosis
mlx04210  Apoptosis
mlx04215  Apoptosis - multiple species
mlx04623  Cytosolic DNA-sensing pathway
mlx04650  Natural killer cell mediated cytotoxicity
mlx04657  IL-17 signaling pathway
mlx04668  TNF signaling pathway
mlx04726  Serotonergic synapse
mlx04932  Non-alcoholic fatty liver disease
mlx04933  AGE-RAGE signaling pathway in diabetic complications
mlx04936  Alcoholic liver disease
mlx05010  Alzheimer disease
mlx05012  Parkinson disease
mlx05014  Amyotrophic lateral sclerosis
mlx05016  Huntington disease
mlx05020  Prion disease
mlx05022  Pathways of neurodegeneration - multiple diseases
mlx05132  Salmonella infection
mlx05133  Pertussis
mlx05134  Legionellosis
mlx05145  Toxoplasmosis
mlx05146  Amoebiasis
mlx05152  Tuberculosis
mlx05160  Hepatitis C
mlx05161  Hepatitis B
mlx05162  Measles
mlx05163  Human cytomegalovirus infection
mlx05164  Influenza A
mlx05165  Human papillomavirus infection
mlx05167  Kaposi sarcoma-associated herpesvirus infection
mlx05168  Herpes simplex virus 1 infection
mlx05169  Epstein-Barr virus infection
mlx05170  Human immunodeficiency virus 1 infection
mlx05200  Pathways in cancer
mlx05203  Viral carcinogenesis
mlx05205  Proteoglycans in cancer
mlx05206  MicroRNAs in cancer
mlx05210  Colorectal cancer
mlx05222  Small cell lung cancer
mlx05416  Viral myocarditis
mlx05417  Lipid and atherosclerosis
Brite
KEGG Orthology (KO) [BR:mlx00001]
 09130 Environmental Information Processing
  09132 Signal transduction
   04010 MAPK signaling pathway
    118010074 (CASP3)
   04668 TNF signaling pathway
    118010074 (CASP3)
 09140 Cellular Processes
  09141 Transport and catabolism
   04148 Efferocytosis
    118010074 (CASP3)
  09143 Cell growth and death
   04210 Apoptosis
    118010074 (CASP3)
   04215 Apoptosis - multiple species
    118010074 (CASP3)
   04115 p53 signaling pathway
    118010074 (CASP3)
 09150 Organismal Systems
  09151 Immune system
   04623 Cytosolic DNA-sensing pathway
    118010074 (CASP3)
   04650 Natural killer cell mediated cytotoxicity
    118010074 (CASP3)
   04657 IL-17 signaling pathway
    118010074 (CASP3)
  09156 Nervous system
   04726 Serotonergic synapse
    118010074 (CASP3)
 09160 Human Diseases
  09161 Cancer: overview
   05200 Pathways in cancer
    118010074 (CASP3)
   05206 MicroRNAs in cancer
    118010074 (CASP3)
   05205 Proteoglycans in cancer
    118010074 (CASP3)
   05203 Viral carcinogenesis
    118010074 (CASP3)
  09162 Cancer: specific types
   05210 Colorectal cancer
    118010074 (CASP3)
   05222 Small cell lung cancer
    118010074 (CASP3)
  09172 Infectious disease: viral
   05170 Human immunodeficiency virus 1 infection
    118010074 (CASP3)
   05161 Hepatitis B
    118010074 (CASP3)
   05160 Hepatitis C
    118010074 (CASP3)
   05164 Influenza A
    118010074 (CASP3)
   05162 Measles
    118010074 (CASP3)
   05168 Herpes simplex virus 1 infection
    118010074 (CASP3)
   05163 Human cytomegalovirus infection
    118010074 (CASP3)
   05167 Kaposi sarcoma-associated herpesvirus infection
    118010074 (CASP3)
   05169 Epstein-Barr virus infection
    118010074 (CASP3)
   05165 Human papillomavirus infection
    118010074 (CASP3)
  09171 Infectious disease: bacterial
   05132 Salmonella infection
    118010074 (CASP3)
   05133 Pertussis
    118010074 (CASP3)
   05134 Legionellosis
    118010074 (CASP3)
   05152 Tuberculosis
    118010074 (CASP3)
  09174 Infectious disease: parasitic
   05146 Amoebiasis
    118010074 (CASP3)
   05145 Toxoplasmosis
    118010074 (CASP3)
  09164 Neurodegenerative disease
   05010 Alzheimer disease
    118010074 (CASP3)
   05012 Parkinson disease
    118010074 (CASP3)
   05014 Amyotrophic lateral sclerosis
    118010074 (CASP3)
   05016 Huntington disease
    118010074 (CASP3)
   05020 Prion disease
    118010074 (CASP3)
   05022 Pathways of neurodegeneration - multiple diseases
    118010074 (CASP3)
  09166 Cardiovascular disease
   05417 Lipid and atherosclerosis
    118010074 (CASP3)
   05416 Viral myocarditis
    118010074 (CASP3)
  09167 Endocrine and metabolic disease
   04936 Alcoholic liver disease
    118010074 (CASP3)
   04932 Non-alcoholic fatty liver disease
    118010074 (CASP3)
   04933 AGE-RAGE signaling pathway in diabetic complications
    118010074 (CASP3)
  09176 Drug resistance: antineoplastic
   01524 Platinum drug resistance
    118010074 (CASP3)
 09180 Brite Hierarchies
  09181 Protein families: metabolism
   01002 Peptidases and inhibitors [BR:mlx01002]
    118010074 (CASP3)
Enzymes [BR:mlx01000]
 3. Hydrolases
  3.4  Acting on peptide bonds (peptidases)
   3.4.22  Cysteine endopeptidases
    3.4.22.56  caspase-3
     118010074 (CASP3)
Peptidases and inhibitors [BR:mlx01002]
 Cysteine peptidases
  Family C14: caspase family
   118010074 (CASP3)
SSDB
Motif
Pfam: Peptidase_C14
Other DBs
NCBI-GeneID: 118010074
NCBI-ProteinID: XP_034860153
LinkDB
Position
Unknown
AA seq 302 aa
MGSTFTSGRPEKTWENSGRQVLEVSMENTEHSVDAKSIKNSETKILHGSKSVDSGMFLDN
SYKMDYPEMGLCIIINNKNFHRSTGMTPRSGTDVDAANLRETFTNLKYEVRNKNDLTCEE
ILELMDSVSKEDHSKRSSFVCVLLSHGDEGIIFGTNGPIDLKKLTGFFRGDYCRSLTGKP
KLFIIQACRGTELDCGIETDSGTEDDMTCQKIPVEADFLYAYSTAPGYYSWRNSKDGSWF
IQSLCMMLKLYAYKLEFMHILTRVNRKVATEFESFSLDSAFHGKKQIPCIVSMLTKELYL
YH
NT seq 909 nt   +upstreamnt  +downstreamnt
atgggaagtacctttacttctggaaggccagagaagacatgggagaactccggaagacaa
gtattagaagtatccatggagaacactgaacactcagtggatgcaaaatccattaaaaat
tcagaaacaaagatcttacatggaagcaaatcagtggactctggaatgttcttggacaac
agttataaaatggattatcctgaaatgggtttatgtataataattaataataagaacttt
catagaagtactggaatgacacctcgatctggtacagatgtagatgcagcaaacctccgg
gaaacattcacaaacttgaaatatgaagtcaggaataaaaatgatctcacatgtgaagaa
attttggaattaatggacagtgtctctaaagaagatcacagcaaaaggagcagttttgtt
tgcgtgcttctaagccatggggatgaaggaataatttttggaacaaatggacccattgac
ctgaaaaaattaacaggtttcttcagaggggattattgtcgaagtctgactggaaaaccc
aaacttttcattattcaggcctgccgaggcacagaactggactgcggtattgagacagac
agtggaaccgaggatgacatgacctgtcagaaaataccagttgaagcagacttcttgtat
gcctattctacagcccctggttactattcctggcgaaattcaaaggatggatcctggttc
atccagtcactttgtatgatgctgaaactatatgcttacaagcttgaatttatgcacatt
cttacccgggttaaccgaaaggtagccacagaatttgagtccttttctcttgattctgct
tttcatggaaagaaacagattccgtgtattgtgtctatgctcacaaaagaactgtatctt
tatcactaa

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