Mirounga leonina (Southern elephant seal): 118015655
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Entry
118015655 CDS
T07472
Symbol
TH
Name
(RefSeq) tyrosine 3-monooxygenase isoform X1
KO
K00501
tyrosine 3-monooxygenase [EC:
1.14.16.2
]
Organism
mlx
Mirounga leonina (Southern elephant seal)
Pathway
mlx00350
Tyrosine metabolism
mlx00790
Folate biosynthesis
mlx01100
Metabolic pathways
mlx04728
Dopaminergic synapse
mlx04917
Prolactin signaling pathway
mlx05012
Parkinson disease
mlx05030
Cocaine addiction
mlx05031
Amphetamine addiction
mlx05034
Alcoholism
Module
mlx_M00042
Catecholamine biosynthesis, tyrosine => dopamine => noradrenaline => adrenaline
Brite
KEGG Orthology (KO) [BR:
mlx00001
]
09100 Metabolism
09105 Amino acid metabolism
00350 Tyrosine metabolism
118015655 (TH)
09108 Metabolism of cofactors and vitamins
00790 Folate biosynthesis
118015655 (TH)
09150 Organismal Systems
09152 Endocrine system
04917 Prolactin signaling pathway
118015655 (TH)
09156 Nervous system
04728 Dopaminergic synapse
118015655 (TH)
09160 Human Diseases
09164 Neurodegenerative disease
05012 Parkinson disease
118015655 (TH)
09165 Substance dependence
05030 Cocaine addiction
118015655 (TH)
05031 Amphetamine addiction
118015655 (TH)
05034 Alcoholism
118015655 (TH)
Enzymes [BR:
mlx01000
]
1. Oxidoreductases
1.14 Acting on paired donors, with incorporation or reduction of molecular oxygen
1.14.16 With reduced pteridine as one donor, and incorporation of one atom of oxygen into the other donor
1.14.16.2 tyrosine 3-monooxygenase
118015655 (TH)
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Paralog
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Motif
Pfam:
Biopterin_H
TH_ACT
TOH_N
LTP_2
Motif
Other DBs
NCBI-GeneID:
118015655
NCBI-ProteinID:
XP_034868293
LinkDB
All DBs
Position
Unknown
AA seq
524 aa
AA seq
DB search
MPTPSSASPQAKGFRRAVSELDAKQAEAIMVRGLLGPPSLAGAPRPGAAALLCSHPRGQS
PRFIGRRQSLIEDARKEREKAEAASAASSEPGDPLEAAVFKDKDGKAMLNLLFTLRGAKT
ASLSRAVKAFETFEAQIHHLETRPAQKPRAGGPHLEYFVRCEVPSADLPALLSSVRRVAE
DVRGAGENKVLWFPRKVSELDKCHHLVTKFDPDLDLDHPGFSDQAYRQRRKLIAEIAFQY
KHGDPIPRVEYTAEEIATWKEVYTTLKGLYATHACREHLEAFQLLERFSGYREDSIPQLE
DVSRFLKERTGFQLRPVAGLLSARDFLASLAFRVFQCTQYIRHASSPMHSPEPDCCHELL
GHVPMLADRTFAQFSQDIGLASLGASDEEIEKLSTLYWFTVEFGLCKQNGEVKAYGAGLL
SSYGELLHSLSEEPEIRAFDPDAAAVQPYQDQTYQSVYFVSESFSDAKDKLRNYASRIQR
PFSVKFDPYTLAIDVLDSPHAIRRSLEGVQDELHTLTHALSAIS
NT seq
1575 nt
NT seq
+upstream
nt +downstream
nt
atgcccactcccagctctgcctcgccccaggccaagggcttccgcagggcggtctccgag
ctggatgccaagcaggccgaagccatcatggtaagggggctgctgggcccacccagcctt
gcaggtgctccccgacccggggctgcagccctgctctgctcacacccccgaggccaatcc
ccgcgcttcatcgggcggcgacagagcctcatcgaggacgctcgcaaggagcgagagaag
gccgaggccgcgtcggccgcctcctcggagcccggggaccccctagaggccgcagtgttc
aaggacaaggacgggaaggccatgctgaatctgctcttcaccctccggggcgccaagacc
gcgtcgctgtcccgggccgtgaaggcatttgagacgtttgaagcccaaatccaccatctg
gagacccggcccgcccagaagccacgggcagggggcccccacctggagtactttgtgcgc
tgtgaggtgcccagtgccgacctgcccgccctgctcagctccgtgcgccgggtggcagag
gacgtgcgtggtgctggggagaacaaggtcctctggttcccgaggaaagtttctgagctg
gacaagtgtcaccatctggtcaccaagtttgaccctgacctggacttggatcatccgggc
ttctcggaccaggcttaccgccagcgccggaagctgatcgcggagatcgcattccagtac
aagcacggcgaccctattccccgtgtggagtacacggccgaggagattgccacctggaag
gaggtctacaccaccctcaagggcctctacgccacccacgcctgccgggagcacctggag
gccttccagctgctggagcgcttcagcggctaccgggaggacagcatcccccagctggag
gacgtgtcccgcttcctgaaggagcgcacgggcttccagctgcggcccgtggccggcctg
ctgtccgcccgggacttcctggccagcctggccttccgcgtgttccagtgcacccagtac
atccgacatgcgtcctcgcccatgcactcccccgagccggactgttgccatgagctgctg
gggcacgtgcccatgctggccgaccggacctttgctcagttctcccaggacatcgggctt
gcgtccttgggggcttctgacgaggaaatcgagaagctgtccacgctgtactggttcacg
gtggagttcgggctgtgtaagcagaatggcgaggtgaaggcctacggcgcggggctgctg
tcctcctacggggagctcctgcactccctgtctgaggagcctgagatccgggccttcgac
ccggacgctgccgccgtgcagccctaccaggaccagacctaccagtccgtgtactttgtg
tccgaaagcttcagcgatgccaaggacaagctcaggaactacgcttcccgcatccaacgc
cccttctccgtgaagtttgacccgtataccctggccatcgacgtgctggacagtccccac
gcgatccggcgctccctggagggcgtccaggatgagctgcacaccctcacccatgcgctg
agcgccatcagctag
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