Mus musculus (house mouse): 11491
Help
Entry
11491 CDS
T01002
Symbol
Adam17, CD156b, Tace
Name
(RefSeq) disintegrin and metalloproteinase domain-containing protein 17 isoform 1 preproprotein
KO
K06059
disintegrin and metalloproteinase domain-containing protein 17 [EC:
3.4.24.86
]
Organism
mmu
Mus musculus (house mouse)
Pathway
mmu04148
Efferocytosis
mmu04330
Notch signaling pathway
mmu04668
TNF signaling pathway
mmu05010
Alzheimer disease
mmu05171
Coronavirus disease
Brite
KEGG Orthology (KO) [BR:
mmu00001
]
09130 Environmental Information Processing
09132 Signal transduction
04330 Notch signaling pathway
11491 (Adam17)
04668 TNF signaling pathway
11491 (Adam17)
09140 Cellular Processes
09141 Transport and catabolism
04148 Efferocytosis
11491 (Adam17)
09160 Human Diseases
09172 Infectious disease: viral
05171 Coronavirus disease
11491 (Adam17)
09164 Neurodegenerative disease
05010 Alzheimer disease
11491 (Adam17)
09180 Brite Hierarchies
09181 Protein families: metabolism
01002 Peptidases and inhibitors [BR:
mmu01002
]
11491 (Adam17)
09183 Protein families: signaling and cellular processes
04090 CD molecules [BR:
mmu04090
]
11491 (Adam17)
Enzymes [BR:
mmu01000
]
3. Hydrolases
3.4 Acting on peptide bonds (peptidases)
3.4.24 Metalloendopeptidases
3.4.24.86 ADAM 17 endopeptidase
11491 (Adam17)
Peptidases and inhibitors [BR:
mmu01002
]
Metallo peptidases
Family M12: astacin/adamalysin family
11491 (Adam17)
CD molecules [BR:
mmu04090
]
Proteins
11491 (Adam17)
SSDB
Ortholog
Paralog
GFIT
Motif
Pfam:
Reprolysin_2
Reprolysin_5
ADAM17_MPD
Disintegrin
Reprolysin_3
Reprolysin
Reprolysin_4
Pep_M12B_propep
Motif
Other DBs
NCBI-GeneID:
11491
NCBI-ProteinID:
NP_033745
MGI:
1096335
Ensembl:
ENSMUSG00000052593
UniProt:
Q9Z0F8
LinkDB
All DBs
Position
12:complement(21373510..21423633)
Genome browser
AA seq
827 aa
AA seq
DB search
MRRRLLILTTLVPFVLAPRPPEEAGSGSHPRLEKLDSLLSDYDILSLANIQQHSIRKRDL
QSATHLETLLTFSALKRHFKLYLTSSTERFSQNLRVVVVDGKEESEYSVKWQNFFSGHVV
GEPDSRVLAHIGDDDVTVRINTDGAEYNVEPLWRFVNDTKDKRMLVYKSEDIKDFSRLQS
PKVCGYLNADSEELLPKGLIDREPSEEFVRRVKRRAEPNPLKNTCKLLVVADHRFYKYMG
RGEESTTTNYLIELIDRVDDIYRNTSWDNAGFKGYGVQIEQIRILKSPQEVKPGERHFNM
AKSFPNEEKDAWDVKMLLEQFSFDIAEEASKVCLAHLFTYQDFDMGTLGLAYVGSPRANS
HGGVCPKAYYNPTVKKNIYLNSGLTSTKNYGKTILTKEADLVTTHELGHNFGAEHDPDGL
AECAPNEDQGGKYVMYPIAVSGDHENNKMFSNCSKQSIYKTIESKAQECFQERSNKVCGN
SRVDEGEECDPGIMYLNNDTCCNSDCTLKPGVQCSDRNSPCCKNCQFETAQKKCQEAINA
TCKGVSYCTGNSSECPPPGDAEDDTVCLDLGKCKAGKCIPFCKREQELESCACVDTDNSC
KVCCRNLSGPCVPYVDAEQKNLFLRKGKPCTVGFCDMNGKCEKRVQDVIERFWDFIDQLS
INTFGKFLADNIVGSVLVFSLIFWIPFSILVHCVDKKLDKQYESLSLFHHSNIEMLSSMD
SASVRIIKPFPAPQTPGRLQALQPAAMMPPVPAAPKLDHQRMDTIQEDPSTDSHADDDGF
EKDPFPNSSTAAKSFEDLTDHPVTRSEKAASFKLQRQSRVDSKETEC
NT seq
2484 nt
NT seq
+upstream
nt +downstream
nt
atgaggcggcgtctcctcatcctgaccactttggtgcctttcgtcctggcaccccgacct
ccggaggaagcaggctctggctcccatccgcgacttgagaagcttgattctttgctctca
gactacgacatcctctccttagctaatattcagcagcactccataaggaaaagggatcta
cagtctgcgacacacttagaaacattactaactttttcagctttgaaaagacattttaaa
ttatacttgacatcaagtaccgaacgcttttcacaaaacttgagagtcgtggtggtggac
gggaaagaagaaagcgagtacagcgtgaagtggcagaacttcttcagtggtcacgtggtt
ggtgagcctgactctagggttctagcccacataggagatgatgatgttacagtgagaatc
aacacagatggggcagaatataacgtagagccactttggaggtttgtcaatgatactaaa
gataaacgaatgctggtgtataagtctgaagatatcaaggatttttcacgtttgcagtct
ccaaaagtatgtggttatttaaatgcagatagtgaagagctgcttccaaaagggctcata
gacagagagccatctgaagagtttgttcgtcgagtgaagagacgagctgaacctaacccc
ttgaagaatacttgtaaattactggtggtagcagatcatcgattttataaatacatgggc
cgtggagaagagagcaccactacaaattacttaatagagctaattgaccgagttgatgac
atataccggaacacgtcgtgggataatgcagggtttaaagggtatggagtgcagatagag
cagattcgaattctcaagtctccacaagaggtaaaacctggtgaaagacacttcaatatg
gcaaaaagtttcccaaacgaagagaaggatgcttgggatgtgaagatgctattagagcaa
tttagctttgatatagctgaagaagcatctaaagtctgcctggctcatcttttcacgtac
caggattttgatatgggaactcttggattagcttacgttggttctcccagagcaaacagt
catggaggggtttgtccaaaagcttattacaacccaactgtgaagaaaaacatctattta
aatagtggtctgactagtactaaaaattatggcaaaactattctcacaaaggaagctgac
ctggttacaactcatgaattgggacataattttggagcagaacatgaccctgatgggcta
gcagaatgtgccccaaatgaggaccaaggaggaaagtatgtcatgtatcccatagctgtg
agcggtgaccacgagaataataagatgttttcaaactgcagtaaacagtccatctacaag
accatagaaagtaaggctcaagagtgcttccaggagcgcagcaacaaggtgtgtggcaac
tccagggtggatgaaggagaggagtgtgacccgggtattatgtacctgaacaacgacacc
tgctgcaatagtgactgcacactgaagccgggtgtgcagtgcagtgataggaacagtcct
tgctgtaaaaactgtcagtttgagacggcgcagaagaagtgccaggaggctattaatgct
acatgcaaaggagtgtcttactgcacagggaatagcagtgagtgccccccacccggagat
gctgaagatgacactgtgtgcttggaccttggcaagtgcaaggctgggaaatgcatccct
ttctgcaagagggagcaggagctggagtcctgcgcatgcgttgacactgacaactcgtgc
aaggtgtgctgcaggaacctttctggcccgtgtgtgccgtacgtcgatgcagagcaaaag
aacttgtttttgaggaaagggaagccatgtacagtagggttttgcgacatgaatggcaaa
tgtgagaaacgagtacaggacgtaattgagcgattttgggatttcattgaccagctgagc
atcaacacttttgggaagtttctggcagataacatcgttgggtctgttctggttttctcc
ttgatattttggattcctttcagcattcttgtccactgtgtggataagaaactggacaag
cagtatgaatccctgtctctgtttcatcacagtaacattgagatgctgagcagcatggac
tcagcatctgttcgcatcatcaagccctttcctgcaccccagactccaggtcgtctgcag
gccctgcagccagctgccatgatgccgccagtacctgcagctccaaaactggaccaccag
aggatggacaccatccaggaagaccccagcacagactcacatgcagatgatgacggtttt
gagaaggaccccttccccaacagcagcacagctgccaagtcctttgaggatctcacagac
cacccagtcaccaggagcgaaaaggcggcctcattcaagctgcagcgtcagagccgagtt
gacagcaaagagacagagtgctag
DBGET
integrated database retrieval system
