Mus musculus (house mouse): 11689
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Entry
11689 CDS
T01002
Symbol
Alox5, 5-LO, 5-LOX, 5LO, 5LX, F730011J02
Name
(RefSeq) arachidonate 5-lipoxygenase
KO
K00461
arachidonate 5-lipoxygenase [EC:
1.13.11.34
]
Organism
mmu
Mus musculus (house mouse)
Pathway
mmu00590
Arachidonic acid metabolism
mmu01100
Metabolic pathways
mmu04148
Efferocytosis
mmu04664
Fc epsilon RI signaling pathway
mmu04726
Serotonergic synapse
mmu04913
Ovarian steroidogenesis
mmu05145
Toxoplasmosis
Brite
KEGG Orthology (KO) [BR:
mmu00001
]
09100 Metabolism
09103 Lipid metabolism
00590 Arachidonic acid metabolism
11689 (Alox5)
09140 Cellular Processes
09141 Transport and catabolism
04148 Efferocytosis
11689 (Alox5)
09150 Organismal Systems
09151 Immune system
04664 Fc epsilon RI signaling pathway
11689 (Alox5)
09152 Endocrine system
04913 Ovarian steroidogenesis
11689 (Alox5)
09156 Nervous system
04726 Serotonergic synapse
11689 (Alox5)
09160 Human Diseases
09174 Infectious disease: parasitic
05145 Toxoplasmosis
11689 (Alox5)
Enzymes [BR:
mmu01000
]
1. Oxidoreductases
1.13 Acting on single donors with incorporation of molecular oxygen (oxygenases)
1.13.11 With incorporation of two atoms of oxygen
1.13.11.34 arachidonate 5-lipoxygenase
11689 (Alox5)
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SSDB
Ortholog
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Gene cluster
GFIT
Motif
Pfam:
Lipoxygenase
PLAT
Motif
Other DBs
NCBI-GeneID:
11689
NCBI-ProteinID:
NP_033792
MGI:
87999
Ensembl:
ENSMUSG00000025701
UniProt:
P48999
LinkDB
All DBs
Position
6:complement(116387030..116438139)
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AA seq
674 aa
AA seq
DB search
MPSYTVTVATGSQWFAGTDDYIYLSLIGSAGCSEKHLLDKAFYNDFERGAVDSYDVTVDE
ELGEIYLVKIEKRKYWLHDDWYLKYITLKTPHGDYIEFPCYRWITGEGEIVLRDGRAKLA
RDDQIHILKQHRRKELEARQKQYRWMEWNPGFPLSIDAKCHKDLPRDIQFDSEKGVDFVL
NYSKAMENLFINRFMHMFQSSWHDFADFEKIFVKISNTISERVKNHWQEDLMFGYQFLNG
CNPVLIKRCTALPPKLPVTTEMVECSLERQLSLEQEVQEGNIFIVDYELLDGIDANKTDP
CTHQFLAAPICLLYKNLANKIVPIAIQLNQTPGESNPIFLPTDSKYDWLLAKIWVRSSDF
HVHQTITHLLRTHLVSEVFGIAMYRQLPAVHPLFKLLVAHVRFTIAINTKAREQLICEYG
LFDKANATGGGGHVQMVQRAVQDLTYSSLCFPEAIKARGMDSTEDIPFYFYRDDGLLVWE
AIQSFTMEVVSIYYENDQVVEEDQELQDFVKDVYVYGMRGKKASGFPKSIKSREKLSEYL
TVVIFTASAQHAAVNFGQYDWCSWIPNAPPTMRAPPPTAKGVVTIEQIVDTLPDRGRSCW
HLGAVWALSQFQENELFLGMYPEEHFIEKPVKEAMIRFRKNLEAIVSVIAERNKNKKLPY
YYLSPDRIPNSVAI
NT seq
2025 nt
NT seq
+upstream
nt +downstream
nt
atgccctcctacacggtcaccgtggccaccggcagccagtggttcgcgggcaccgacgac
tacatctacctcagcctcattggctctgcgggctgtagcgagaagcatctgctggacaag
gcattctacaatgacttcgaacggggcgcggtggactcctacgatgtcaccgtggatgag
gagctgggcgagatctacctagtcaaaattgagaagcgcaaatactggctccatgatgac
tggtacctgaagtacatcacactgaagacaccccacggggactacatcgagttcccatgt
taccgctggatcacaggcgagggcgagattgtcctgagggatggacgtgcaaaattggcc
cgagatgaccaaattcacatcctcaagcagcacagacgtaaagaactggaggcacggcaa
aaacagtatcgatggatggagtggaaccccggcttccctttgagtattgatgccaaatgc
cacaaggatctgccccgagatatccagtttgatagtgaaaaaggagtggactttgttctg
aactactcaaaagcgatggagaacctgttcatcaaccgcttcatgcacatgttccagtct
tcctggcacgactttgctgactttgagaaaatcttcgtcaaaatcagcaacactatatct
gagcgagtcaagaaccactggcaggaagacctcatgtttggctaccagttcctgaatggc
tgcaacccagtactcatcaagcgctgcacagcgttgcccccgaagctcccagtgaccaca
gagatggtggagtgcagcctagagcggcagctcagtttagaacaggaagtacaggaaggg
aacattttcatcgttgattacgagctactggatggcatcgatgctaacaaaactgacccc
tgtacacaccagttcctggctgcccccatctgcctgctatataagaacctagccaacaag
attgttcccattgccatccagctcaaccaaacccctggagagagtaacccaatcttcctc
cctacggattcaaagtacgactggcttttggccaaaatctgggtgcgttccagtgacttc
cacgtccatcaaacgatcacccaccttctgcgcacgcatctggtgtctgaggtgtttggt
atcgccatgtaccgccagctgcctgctgtgcatccccttttcaagctgctggtagcccat
gtgaggttcaccattgctatcaacactaaggcccgggaacagcttatctgcgagtatggc
ctttttgacaaggccaatgccaccgggggtggagggcacgtgcagatggtgcagagggct
gtccaggatctgacctattcctccctgtgtttcccggaggccatcaaggcccggggcatg
gacagcacggaagacatccccttctacttctatcgtgatgatggactgctcgtgtgggag
gctatccagtcgttcacaatggaggtggtgagcatctactatgagaacgaccaggtggtg
gaggaggaccaggaactgcaggacttcgtgaaggatgtttacgtgtacggcatgcggggc
aaaaaggcctcaggtttccccaagtccatcaagagcagggagaagctgtccgagtacctg
acggtggtgatcttcacggcctctgcccagcatgcagctgtaaacttcggccagtatgac
tggtgctcctggatccccaacgctcctccaactatgcgggccccaccacccacggccaag
ggtgtggtcaccatcgagcagatcgtggatactctaccagaccgtggccgatcatgttgg
catctaggtgcagtgtgggccttgagccagtttcaagaaaatgagctgtttctaggcatg
tacccagaggagcatttcattgagaagccagtgaaggaagccatgatccgattccgcaag
aacctggaggccatcgtcagcgtgatcgccgagcgcaataagaacaaaaagctcccctac
tactacctgtcaccagacaggattcccaacagcgtagccatctaa
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