Mus musculus (house mouse): 14061
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Entry
14061 CDS
T01002
Symbol
F2, Cf-2, Cf2, FII
Name
(RefSeq) coagulation factor II
KO
K01313
coagulation factor II (thrombin) [EC:
3.4.21.5
]
Organism
mmu
Mus musculus (house mouse)
Pathway
mmu04072
Phospholipase D signaling pathway
mmu04080
Neuroactive ligand-receptor interaction
mmu04610
Complement and coagulation cascades
mmu04611
Platelet activation
mmu04810
Regulation of actin cytoskeleton
mmu05171
Coronavirus disease - COVID-19
mmu05200
Pathways in cancer
Brite
KEGG Orthology (KO) [BR:
mmu00001
]
09130 Environmental Information Processing
09132 Signal transduction
04072 Phospholipase D signaling pathway
14061 (F2)
09133 Signaling molecules and interaction
04080 Neuroactive ligand-receptor interaction
14061 (F2)
09140 Cellular Processes
09142 Cell motility
04810 Regulation of actin cytoskeleton
14061 (F2)
09150 Organismal Systems
09151 Immune system
04610 Complement and coagulation cascades
14061 (F2)
04611 Platelet activation
14061 (F2)
09160 Human Diseases
09161 Cancer: overview
05200 Pathways in cancer
14061 (F2)
09172 Infectious disease: viral
05171 Coronavirus disease - COVID-19
14061 (F2)
09180 Brite Hierarchies
09181 Protein families: metabolism
01002 Peptidases and inhibitors [BR:
mmu01002
]
14061 (F2)
09183 Protein families: signaling and cellular processes
04147 Exosome [BR:
mmu04147
]
14061 (F2)
00536 Glycosaminoglycan binding proteins [BR:
mmu00536
]
14061 (F2)
Enzymes [BR:
mmu01000
]
3. Hydrolases
3.4 Acting on peptide bonds (peptidases)
3.4.21 Serine endopeptidases
3.4.21.5 thrombin
14061 (F2)
Peptidases and inhibitors [BR:
mmu01002
]
Serine peptidases
Family S1: chymotrypsin family
14061 (F2)
Exosome [BR:
mmu04147
]
Exosomal proteins
Exosomal proteins of hepatic cells
14061 (F2)
Glycosaminoglycan binding proteins [BR:
mmu00536
]
Heparan sulfate / Heparin
Coagulation and fibrinolysis
14061 (F2)
BRITE hierarchy
SSDB
Ortholog
Paralog
GFIT
Motif
Pfam:
Trypsin
Kringle
Thrombin_light
Gla
DUF1986
Trypsin_2
Motif
Other DBs
NCBI-GeneID:
14061
NCBI-ProteinID:
NP_034298
MGI:
88380
Ensembl:
ENSMUSG00000027249
UniProt:
P19221
Q3TJ94
Structure
PDB
PDBj
LinkDB
All DBs
Position
2:complement(91442742..91466799)
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AA seq
618 aa
AA seq
DB search
MSHVRGLGLPGCLALAALVSLVHSQHVFLAPQQALSLLQRVRRANSGFLEELRKGNLERE
CVEEQCSYEEAFEALESPQDTDVFWAKYTVCDSVRKPRETFMDCLEGRCAMDLGVNYLGT
VNVTHTGIQCQLWRSRYPHKPEINSTTHPGADLKENFCRNPDSSTTGPWCYTTDPTVRRE
ECSVPVCGQEGRTTVVMTPRSGGSKDNLSPPLGQCLTERGRLYQGNLAVTTLGSPCLPWN
SLPAKTLSKYQDFDPEVKLVENFCRNPDWDEEGAWCYVAGQPGDFEYCNLNYCEEAVGEE
NYDVDESIAGRTTDAEFHTFFNEKTFGLGEADCGLRPLFEKKSLKDTTEKELLDSYIDGR
IVEGWDAEKGIAPWQVMLFRKSPQELLCGASLISDRWVLTAAHCILYPPWDKNFTENDLL
VRIGKHSRTRYERNVEKISMLEKIYVHPRYNWRENLDRDIALLKLKKPVPFSDYIHPVCL
PDKQTVTSLLRAGYKGRVTGWGNLRETWTTNINEIQPSVLQVVNLPIVERPVCKASTRIR
ITDNMFCAGFKVNDTKRGDACEGDSGGPFVMKSPFNNRWYQMGIVSWGEGCDRKGKYGFY
THVFRLKRWIQKVIDQFG
NT seq
1857 nt
NT seq
+upstream
nt +downstream
nt
atgtcgcacgtccgcggcctgggcctccctggctgcttggctctggctgccctggttagc
ctggtacacagccagcatgtgttcctggcgcctcagcaagcactatcgctgctccagcgg
gtccgcagagccaacagtggcttcctggaggagctccgaaagggcaacctagagcgtgag
tgcgtggaagagcagtgcagctatgaggaggcctttgaggccctggagtctccccaagac
acagacgtgttctgggccaagtacacagtgtgtgattcagtgaggaaacctcgagagact
ttcatggactgtctggaaggtcgctgtgctatggatctgggtgtgaactaccttgggact
gtgaatgtcacccataccggtatccagtgccagctgtggcggagccgctacccccacaag
cctgaaatcaactccaccacccatcctggggcagacctgaaggagaacttctgccgcaat
ccagacagcagtaccacgggaccctggtgctacaccacagatcctactgtgcgcagagag
gaatgcagtgtccctgtctgtggccaggagggccgtaccactgtggtgatgactcctcgc
tctggaggttccaaggacaatctgtcacctccactgggacagtgcctcactgagcgtggc
cgactataccaggggaatttggctgtgacaacacttgggtccccctgcctgccctggaac
agcttaccagccaagaccctgagcaagtaccaagacttcgaccccgaggtgaaactcgtg
gaaaacttctgccgcaacccagactgggatgaggagggcgcatggtgctatgttgcgggg
cagcctggcgactttgaatactgcaacctcaactactgcgaggaggcggtgggagaggag
aactatgatgtggacgagtccatcgcgggacgcaccaccgatgcggagttccacaccttc
ttcaatgagaagaccttcggccttggggaggcagactgtggcctgcggcctttgttcgag
aagaagtcgttgaaagacacaaccgaaaaggagcttcttgactcttacatagacgggcgc
atcgtggagggctgggacgctgagaagggtatcgccccctggcaggtgatgctttttcgg
aagagtccccaagagctgctgtgtggggccagccttatcagtgaccgatgggtcctcact
gctgcccactgcattctgtacccaccctgggacaagaacttcactgagaatgacctcctg
gtgcgcattggcaagcattcccgaaccagatatgagcggaatgttgaaaagatctccatg
ctggaaaagatctacgtccaccccagatataactggcgggagaacctagaccgcgatatc
gctctgctcaagctaaagaaacctgtacccttcagtgactatattcaccccgtgtgtttg
ccagacaagcagacagtaaccagcttgctccgggctggttataaagggcgggtgacaggc
tggggcaaccttcgggagacatggacaaccaacatcaatgagatacagcccagcgtcctg
caggtggtgaacctgcccattgtagagcggccagtgtgcaaggcctccacccggattcga
attactgacaacatgttctgtgctggcttcaaggtgaatgacaccaagcgaggagatgct
tgtgaaggtgacagtggaggaccttttgtcatgaagagcccctttaacaaccgctggtat
caaatgggtattgtctcatggggtgaaggatgtgaccggaaggggaaatacggcttctac
acgcatgtgttccgtctgaaaaggtggatacagaaagtcattgatcaatttggatag
DBGET
integrated database retrieval system
