Mus musculus (house mouse): 97212
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Entry
97212 CDS
T01002
Symbol
Hadha, MLCL_AT, Mtpa, TP-alpha
Name
(RefSeq) hydroxyacyl-CoA dehydrogenase trifunctional multienzyme complex subunit alpha
KO
K07515
enoyl-CoA hydratase / long-chain 3-hydroxyacyl-CoA dehydrogenase [EC:
4.2.1.17
1.1.1.211
]
Organism
mmu
Mus musculus (house mouse)
Pathway
mmu00062
Fatty acid elongation
mmu00071
Fatty acid degradation
mmu00280
Valine, leucine and isoleucine degradation
mmu00310
Lysine degradation
mmu00380
Tryptophan metabolism
mmu00410
beta-Alanine metabolism
mmu00640
Propanoate metabolism
mmu00650
Butanoate metabolism
mmu01100
Metabolic pathways
mmu01212
Fatty acid metabolism
Module
mmu_M00032
Lysine degradation, lysine => saccharopine => acetoacetyl-CoA
mmu_M00085
Fatty acid elongation in mitochondria
mmu_M00087
beta-Oxidation
Brite
KEGG Orthology (KO) [BR:
mmu00001
]
09100 Metabolism
09101 Carbohydrate metabolism
00640 Propanoate metabolism
97212 (Hadha)
00650 Butanoate metabolism
97212 (Hadha)
09103 Lipid metabolism
00062 Fatty acid elongation
97212 (Hadha)
00071 Fatty acid degradation
97212 (Hadha)
09105 Amino acid metabolism
00280 Valine, leucine and isoleucine degradation
97212 (Hadha)
00310 Lysine degradation
97212 (Hadha)
00380 Tryptophan metabolism
97212 (Hadha)
09106 Metabolism of other amino acids
00410 beta-Alanine metabolism
97212 (Hadha)
Enzymes [BR:
mmu01000
]
1. Oxidoreductases
1.1 Acting on the CH-OH group of donors
1.1.1 With NAD+ or NADP+ as acceptor
1.1.1.211 long-chain-3-hydroxyacyl-CoA dehydrogenase
97212 (Hadha)
4. Lyases
4.2 Carbon-oxygen lyases
4.2.1 Hydro-lyases
4.2.1.17 enoyl-CoA hydratase
97212 (Hadha)
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Ortholog
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Gene cluster
GFIT
Motif
Pfam:
3HCDH_N
ECH_1
3HCDH
ECH_2
Motif
Other DBs
NCBI-GeneID:
97212
NCBI-ProteinID:
NP_849209
MGI:
2135593
Ensembl:
ENSMUSG00000025745
UniProt:
Q8BMS1
LinkDB
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Position
5:complement(30324421..30359978)
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AA seq
763 aa
AA seq
DB search
MVASRAIGSLSRFSAFRILRSRGCICRSFTTSSALLTRTHINYGVKGDVAVIRINSPNSK
VNTLNKEVQSEFIEVMNEIWANDQIRSAVLISSKPGCFVAGADINMLSSCTTPQEATRIS
QEGQRMFEKLEKSPKPVVAAISGSCLGGGLELAIACQYRIATKDRKTVLGVPEVLLGILP
GAGGTQRLPKMVGVPAAFDMMLTGRNIRADRAKKMGLVDQLVEPLGPGIKSPEERTIEYL
EEVAVNFAKGLADRKVSAKQSKGLVEKLTTYAMTVPFVRQQVYKTVEEKVKKQTKGLYPA
PLKIIDAVKAGLEQGSDAGYLAESQKFGELALTKESKALMGLYNGQVLCKKNKFGAPQKN
VQQLAILGAGLMGAGIAQVSVDKGLKTLLKDTTVTGLGRGQQQVFKGLNDKVKKKALTSF
ERDSIFSNLIGQLDYKGFEKADMVIEAVFEDLGVKHKVLKEVESVTPEHCIFASNTSALP
INQIAAVSKRPEKVIGMHYFSPVDKMQLLEIITTDKTSKDTTASAVAVGLRQGKVIIVVK
DGPGFYTTRCLAPMMSEVMRILQEGVDPKKLDALTTGFGFPVGAATLADEVGVDVAQHVA
EDLGKAFGERFGGGSVELLKQMVSKGFLGRKSGKGFYIYQEGSKNKSLNSEMDNILANLR
LPAKPEVSSDEDVQYRVITRFVNEAVLCLQEGILATPAEGDIGAVFGLGFPPCLGGPFRF
VDLYGAQKVVDRLRKYESAYGTQFTPCQLLLDHANNSSKKFYQ
NT seq
2292 nt
NT seq
+upstream
nt +downstream
nt
atggtggcgtcccgggcgattggcagtctcagtcgcttctctgccttcaggatcctacgc
tccagaggctgcatttgccgcagctttacaacgtcttctgctctgctgaccagaacccat
attaattatggcgtcaaaggggatgtggcagttattcggattaactcacccaattcaaag
gtaaatacattgaataaagaagtacagtcagagttcatagaagtcatgaacgaaatctgg
gccaacgaccaaatcaggagtgctgtccttatctcatcaaagcctggctgctttgtcgca
ggggctgacatcaacatgctatcctcttgtacaaccccccaagaagcaacacgaatatca
caggaaggtcagagaatgtttgagaaacttgaaaagtccccaaagcccgttgtggccgcc
atcagtggatcctgcttgggaggaggacttgagcttgccatagcatgccaatacagaata
gcaacaaaagacagaaaaacagtattaggtgtccctgaagtgttgctggggatcttacca
ggagccggaggtacccagagactgcccaaaatggtgggtgtgcctgctgcatttgacatg
atgctgactggcaggaacattcgtgcagacagagcaaagaaaatgggactggttgaccag
ttggtggaaccgctgggaccaggaataaaatcaccagaagaaaggacaattgaataccta
gaggaagttgcagttaattttgccaaaggcctggctgatcggaaagtctctgcaaagcag
agcaaaggccttgtggaaaagctgacaacgtatgccatgactgtcccatttgtcagacaa
caggtttacaaaacagttgaagaaaaagtgaagaagcagactaaaggcctttatcctgcc
cctttgaaaataattgatgctgtgaaggctggacttgagcaaggcagtgacgctggttat
cttgctgaatcgcagaaatttggagagcttgcattgaccaaagaatcgaaggccctgatg
gggctttataacggccaggtcctgtgcaagaaaaataaatttggagcaccacagaagaac
gttcagcagctagccatccttggcgcagggctgatgggggctggcattgcccaggtctct
gtggataagggactgaaaactcttcttaaagacaccacagtgacggggctgggccgggga
cagcagcaagtgttcaaagggctgaacgacaaagtgaagaagaaagctctcacatcattt
gaaagggattccatcttcagcaacttgattgggcagctggattacaaaggctttgagaag
gccgacatggtgattgaggctgtgtttgaggacctcggtgtaaagcacaaagtgttaaag
gaagtggaaagcgtgactccagaacactgtatctttgccagcaacacatctgctctccca
atcaatcaaattgctgctgtcagcaaaaggcctgagaaggtgatcggcatgcactacttc
tcccccgtggacaagatgcagctcctagaaatcatcaccactgacaaaacctccaaggac
acaacggcctctgccgtggccgtggggctcaggcaagggaaggtcatcattgtggtcaag
gacggacccggcttctacaccaccaggtgtcttgcacccatgatgtctgaagtcatgcga
atcctccaggaaggagttgaccctaagaagctggacgccttgaccacaggtttcggcttc
cctgtgggtgctgccacgctggcagacgaagtgggtgtggatgtagcacagcacgtagca
gaagatctaggcaaagcctttggggagcgatttggaggtggcagcgtagaactgctgaaa
cagatggtctccaagggcttcttaggtcgcaagtctgggaagggcttttacatctatcag
gagggctcaaagaataagagtttgaattctgaaatggataatatcttggcaaatctgagg
ctgcctgccaagcccgaggtctcctctgatgaagacgtccaataccgtgtgataacaagg
ttcgtgaacgaggcagtcctgtgcctacaggaagggatcctggccacaccggcagaggga
gacatcggagctgtctttgggcttggctttcccccttgtctcggagggcccttccgcttt
gtggatctgtatggtgctcagaaggtagtggaccggctacggaagtacgagtctgcctat
ggaacacagtttaccccatgccagctgctcctcgaccacgctaacaactctagcaagaag
ttctaccagtga
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