Mustela nigripes (black-footed ferret): 132016591
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Entry
132016591 CDS
T09425
Symbol
ALOX5
Name
(RefSeq) polyunsaturated fatty acid 5-lipoxygenase isoform X1
KO
K00461
arachidonate 5-lipoxygenase [EC:
1.13.11.34
]
Organism
mnp
Mustela nigripes (black-footed ferret)
Pathway
mnp00590
Arachidonic acid metabolism
mnp01100
Metabolic pathways
mnp04148
Efferocytosis
mnp04664
Fc epsilon RI signaling pathway
mnp04726
Serotonergic synapse
mnp04913
Ovarian steroidogenesis
mnp05145
Toxoplasmosis
Brite
KEGG Orthology (KO) [BR:
mnp00001
]
09100 Metabolism
09103 Lipid metabolism
00590 Arachidonic acid metabolism
132016591 (ALOX5)
09140 Cellular Processes
09141 Transport and catabolism
04148 Efferocytosis
132016591 (ALOX5)
09150 Organismal Systems
09151 Immune system
04664 Fc epsilon RI signaling pathway
132016591 (ALOX5)
09152 Endocrine system
04913 Ovarian steroidogenesis
132016591 (ALOX5)
09156 Nervous system
04726 Serotonergic synapse
132016591 (ALOX5)
09160 Human Diseases
09174 Infectious disease: parasitic
05145 Toxoplasmosis
132016591 (ALOX5)
Enzymes [BR:
mnp01000
]
1. Oxidoreductases
1.13 Acting on single donors with incorporation of molecular oxygen (oxygenases)
1.13.11 With incorporation of two atoms of oxygen
1.13.11.34 arachidonate 5-lipoxygenase
132016591 (ALOX5)
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Gene cluster
GFIT
Motif
Pfam:
Lipoxygenase
PLAT
Motif
Other DBs
NCBI-GeneID:
132016591
NCBI-ProteinID:
XP_059254005
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Position
4:complement(153106221..153148668)
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AA seq
674 aa
AA seq
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MPSYTVTVATGSQWFAGTDDYIYLSLVGSAGCSEKHLLDKPFYNDFERGAVDSYDVTVDE
ELGEIQLVKIEKRKYWLHDDWYLKYITLKTPYGDYIEFPCYRWITGEGEIVLRDGRAKLA
CDDQIHILKQHRRKELETRQKQYRWMEWNPGFPLSIDAKCHKDLPRDIQFDSEKGVDFVL
NYSRAMENLFINRFMHMFQSSWSDFADFEKIFVKISNTISERVMNHWQEDLMFGYQFLNG
CNPVLIRRCTKLPKKLPVTTEMVECSLERQLTLQQEVEQGNIFIVDFELLDGIDANKTDP
CTLQFLAAPICLLYKNLANKIVPIAIQLNQIPGDENPIFLPSDAKYDWLLAKIWVRSSDF
HVHQTITHLLRTHLVSEVFGIALYRQLPAVHPIFKLLVAHVRFTIAINTKAREQLICEYG
LFDKANATGGGGHVQMVQKAMQDLTYTSLCFPEAIKARGMDSAEDIPNYFYRDDGLLVWE
AIKTFTAEVVGIYYESDQVVAEDQELQDFVNDVYVYGMRGKKTSGFPKSIKTREKLSEYL
TVVIFTASAQHAAVNFGQYDWCSWIPNAPPTMRAPPPTAKGVVTIEQIVDTLPDRGRSCW
HLGAVWALSQFQENELFLGMYPEEHFIEKPVKEAMARFRKNLDTIVSVIAERNKKKKLPY
YYLSPDRIPNSVAI
NT seq
2025 nt
NT seq
+upstream
nt +downstream
nt
atgccgtcctacaccgtcaccgtggccaccggcagccagtggttcgctggcaccgacgac
tacatctacctcagcctcgtgggttctgcgggctgcagcgagaagcacctcctggacaag
cccttctacaacgactttgagcgcggcgcggttgattcctatgatgtgacagtggatgaa
gaactgggcgaaatccagctggtcaaaattgagaagcgcaaatactggctccacgatgac
tggtacctgaagtacatcacgctgaagacgccctacggagattacatcgagttcccatgc
taccgctggatcaccggcgagggcgagatcgtcctgagagacggacgcgcaaagttggcc
tgcgatgaccaaattcacattctcaagcagcacagacgtaaagagctggaaacacggcag
aaacagtatcggtggatggagtggaaccctggcttccctttgagtattgatgccaaatgt
cacaaggatttaccccgagacatccagtttgatagtgagaagggtgtggacttcgttctg
aactactccagagcgatggagaacctgttcatcaaccgcttcatgcacatgttccagtct
tcctggagtgactttgccgatttcgagaaaatctttgtcaagatcagcaacactatttct
gagcgggtcatgaaccactggcaggaagacctcatgtttggctaccagttcctgaatggc
tgcaacccagtgttgatccggcgctgcacgaaactgcccaagaagctccctgtgaccaca
gagatggtggagtgcagcctggagcggcagctcaccttgcagcaggaggttgagcaaggg
aacatcttcatcgtggactttgagctgctggatggcattgatgccaacaaaacagacccc
tgcaccctgcagttcctggcagcgcccatctgcttgctgtacaagaatctggccaacaag
attgtccccattgccatccagctcaaccaaatcccaggagatgaaaacccgattttcctc
ccttcggatgcaaaatatgactggcttctggccaaaatctgggtgcgctccagtgacttc
cacgtccaccagaccatcacccaccttctgcgcacacacctggtatctgaagttttcggc
attgccctgtaccgccagctgcccgccgttcaccccattttcaagcttctggtggcacac
gtgcggttcaccatcgccatcaacaccaaggcccgcgagcagctcatctgcgagtatggc
ctctttgacaaggccaacgccacagggggcggagggcacgtgcagatggtgcagaaggcc
atgcaggacctgacctacacctccctgtgcttccctgaggccatcaaagctcggggaatg
gacagcgcagaggatattcccaactacttctatcgggatgacgggcttctggtgtgggag
gccatcaagacgttcacagccgaggtggtaggcatctactatgagagtgaccaggtggtg
gcagaggaccaggagctgcaggacttcgtgaatgatgtgtacgtgtacggcatgcggggc
aagaagacctcaggtttccccaagtccatcaagaccagagagaagctgtcggagtaccta
acggtagtgatcttcacagcctcagcccagcatgcagcagtcaactttggccagtatgac
tggtgctcctggattcccaatgcccccccaaccatgcgggccccaccaccaacagccaaa
ggtgtggtcaccatcgaacagattgtggatactctgccagaccgtggccgctcctgctgg
catctgggtgcagtgtgggcactaagccagttccaagaaaatgagctgttcctgggcatg
tacccagaagagcatttcatcgagaagcctgtaaaagaggccatggcccgattccgcaag
aaccttgacaccatcgtcagtgtgatcgccgagcgcaacaagaagaagaagctgccgtat
tactacttgtccccagaccggattcccaatagtgtagccatctaa
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