Mustela nigripes (black-footed ferret): 132016827 Help Entry 132016827         CDS       T09425                                  Symbol TH Name (RefSeq) tyrosine 3-monooxygenase   KO K00501   tyrosine 3-monooxygenase [EC:1.14.16.2] Organism mnp  Mustela nigripes (black-footed ferret) Pathway mnp00350   Tyrosine metabolism mnp00790   Folate biosynthesis mnp01100   Metabolic pathways mnp04728   Dopaminergic synapse mnp04917   Prolactin signaling pathway mnp05012   Parkinson disease mnp05030   Cocaine addiction mnp05031   Amphetamine addiction mnp05034   Alcoholism Module mnp_M00042   Catecholamine biosynthesis, tyrosine => dopamine => noradrenaline => adrenaline Brite KEGG Orthology (KO) [BR:mnp00001]  09100 Metabolism   09105 Amino acid metabolism    00350 Tyrosine metabolism     132016827 (TH)   09108 Metabolism of cofactors and vitamins    00790 Folate biosynthesis     132016827 (TH)  09150 Organismal Systems   09152 Endocrine system    04917 Prolactin signaling pathway     132016827 (TH)   09156 Nervous system    04728 Dopaminergic synapse     132016827 (TH)  09160 Human Diseases   09164 Neurodegenerative disease    05012 Parkinson disease     132016827 (TH)   09165 Substance dependence    05030 Cocaine addiction     132016827 (TH)    05031 Amphetamine addiction     132016827 (TH)    05034 Alcoholism     132016827 (TH) Enzymes [BR:mnp01000]  1. Oxidoreductases   1.14  Acting on paired donors, with incorporation or reduction of molecular oxygen    1.14.16  With reduced pteridine as one donor, and incorporation of one atom of oxygen into the other donor     1.14.16.2  tyrosine 3-monooxygenase      132016827 (TH) BRITE hierarchy SSDB OrthologParalogGene clusterGFIT Motif Pfam:  Biopterin_H TH_ACT TOH_N LTP_2 Motif Other DBs NCBI-GeneID:  132016827 NCBI-ProteinID:  XP_059254690 LinkDB All DBs Position 1:complement(1579737..1586924) Genome browser AA seq 495 aa AA seqDB search MPTPNAASPQAKGFRRAVSELDAKQAEAIMSPRFIGRRQSLIEDARKEREKAEAASAASS EPGDPLEAAVFKDKDGKATLNLLFTLRGAKTASLSRAVKAFETFEAQIQHLETRPVQRPR AGGPHLEYFVRCEVPRADLPALLSSVRRVAEDVRGAGENKVLWFPRKVSELDKCHHLVTK FDPDLDLDHPGFSDQAYRQRRKLIAEIAFQYKHGDPIPRVEYTAEEIATWKEVYTTLKGL YVTHACREHLEAFQLLERFSGYREDSIPQLEDVSRFLKERTGFQLRPVAGLLSARDFLAS LAFRVFQCTQYIRHGSSPMHSPEPDCCHELLGHVPMLADRTFAQFSQDIGLASLGASDEE IEKLSTLYWFTVEFGLCKQDGEVKAYGAGLLSSYGELLHSLSAEPEIRAFDPDVVAVQPY QDQTYQSVYFVSESFSDAKSKLRDYASRIQRPFSVKFDPYTLAIDVLDSPQAVRRSLESL QDELYTLTRALGALR NT seq 1488 nt NT seq  +upstreamnt  +downstreamnt atgcccactcccaacgccgcctcgccacaggccaagggcttccgcagggctgtctccgag ctggacgccaagcaggccgaagccatcatgtccccgcgcttcatcgggcggcgacagagc ctcatcgaggacgcccgcaaggagcgagagaaggccgaggctgcgtccgctgcttcctca gagcccggggaccccctagaggctgcagttttcaaggacaaggatgggaaggccacgctg aaccttctcttcacccttcgtggcgccaagaccgcgtccctgtcccgggccgtgaaggct ttcgagacgtttgaagcccaaatccagcacctggagacccggcccgtgcagaggccgcgg gcagggggcccccacctcgagtactttgtgcgctgcgaggtaccccgcgccgacctgccg gccctgctcagctccgtgcgccgggtggcggaggacgtgcgtggcgccggcgagaacaag gtcctctggttcccgaggaaagtttccgaactggacaagtgccaccatctggtcaccaag tttgaccctgacctggacttggatcacccgggtttctcggaccaggcgtaccgccagcgc cggaagctgatcgcggagatcgcattccagtacaagcatggcgaccccattccccgtgtg gagtacacggctgaggagatcgccacctggaaggaggtctacaccaccctcaagggcctg tacgtcacccacgcctgccgggagcacctggaggccttccagctgctggaacgcttcagc gggtaccgggaggacagcatcccccagctggaggacgtgtcccgcttcctgaaggagcgg acaggcttccagctgcggccagtggccggcctgctgtccgcccgggacttcctggccagc ctggccttccgagtgttccagtgcacgcagtacatccggcacgggtcctctcccatgcac tcgcccgagccggactgctgccacgagctgctggggcacgtgcccatgctggccgaccgc acctttgctcaattctcccaggacatcgggctggcctccctgggggcttccgacgaggag attgagaagctgtccacgctgtactggttcacggtggagttcgggctgtgcaagcaggat ggtgaggtgaaagcctacggcgccgggctgctgtcctcctacggggagctcctgcactcc ctgtctgcggagcccgagatccgggcctttgaccccgacgtcgtagccgtgcagccgtac caggaccagacctaccagtccgtgtactttgtgtccgaaagtttcagcgacgccaagagc aagctcagggactacgcttcccgcatccagcgccccttctctgtgaagtttgacccatac acgctggccatcgatgtgctggacagtccccaggctgtccgtcggtccctggagagcctg caggacgagctgtacaccctcacgcgtgcactgggcgccctccgctag

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