Mustela nigripes (black-footed ferret): 132021122
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Entry
132021122 CDS
T09425
Symbol
ADAM17
Name
(RefSeq) disintegrin and metalloproteinase domain-containing protein 17 isoform X1
KO
K06059
disintegrin and metalloproteinase domain-containing protein 17 [EC:
3.4.24.86
]
Organism
mnp
Mustela nigripes (black-footed ferret)
Pathway
mnp04148
Efferocytosis
mnp04330
Notch signaling pathway
mnp04668
TNF signaling pathway
mnp05010
Alzheimer disease
mnp05171
Coronavirus disease - COVID-19
Brite
KEGG Orthology (KO) [BR:
mnp00001
]
09130 Environmental Information Processing
09132 Signal transduction
04330 Notch signaling pathway
132021122 (ADAM17)
04668 TNF signaling pathway
132021122 (ADAM17)
09140 Cellular Processes
09141 Transport and catabolism
04148 Efferocytosis
132021122 (ADAM17)
09160 Human Diseases
09172 Infectious disease: viral
05171 Coronavirus disease - COVID-19
132021122 (ADAM17)
09164 Neurodegenerative disease
05010 Alzheimer disease
132021122 (ADAM17)
09180 Brite Hierarchies
09181 Protein families: metabolism
01002 Peptidases and inhibitors [BR:
mnp01002
]
132021122 (ADAM17)
09183 Protein families: signaling and cellular processes
04090 CD molecules [BR:
mnp04090
]
132021122 (ADAM17)
Enzymes [BR:
mnp01000
]
3. Hydrolases
3.4 Acting on peptide bonds (peptidases)
3.4.24 Metalloendopeptidases
3.4.24.86 ADAM 17 endopeptidase
132021122 (ADAM17)
Peptidases and inhibitors [BR:
mnp01002
]
Metallo peptidases
Family M12: astacin/adamalysin family
132021122 (ADAM17)
CD molecules [BR:
mnp04090
]
Proteins
132021122 (ADAM17)
BRITE hierarchy
SSDB
Ortholog
Paralog
Gene cluster
GFIT
Motif
Pfam:
Reprolysin_5
Reprolysin_2
ADAM17_MPD
Disintegrin
Reprolysin_3
Reprolysin
Reprolysin_4
Pep_M12B_propep
Motif
Other DBs
NCBI-GeneID:
132021122
NCBI-ProteinID:
XP_059261112
LinkDB
All DBs
Position
7:complement(6241362..6293354)
Genome browser
AA seq
822 aa
AA seq
DB search
MRQCLLFLTSVVPFVLAPRPPGDSPERLEKLDSLLSDYDILSLSNIQQHSVRKRDLQAST
HLETLLTFSALKRHFKLYLTSSTEHFSQNFKVVVVDGKDESEYTVKWQDFFRGHVVGEPD
SRVLAHIGDDDITIRINTDGAEYNIEPLWRLINDTKDKRILVYKSEDIKNVSRLQSPKVC
GYIKADNEELLPKGLVDREPPDELVHRVKRRAEPNPMKNTCKLLVVADHRFYRYMGRGEE
STTTNYLIELIDRVDDIYRNTSWDNAGFKGYGIQIEQIRILKSPQEVKPGERHYNMAKSY
PNEEKDAWDVKMLLEQFSFDIAEEASKVCLAHLFTYQDFDMGTLGLAYVGSPRANSHGGV
CPKAYYSPIGKKNIYLNSGLTSTKNYGKTILTKEADLVTTHELGHNFGAEHDPDGLAECA
PNEDQGGKYVMYPIAVSGDHENNKMFSNCSKQSIYKTIESKSQECFQERSNKVCGNSRVD
EGEECDPGIMYLNNDTCCSSDCMLRAGVQCSDRNSPCCKNCQFETAQKKCQEAINATCKG
VSYCTGNSSECPPPGNAADDTVCLDLGKCKDGKCVPFCEREQQRESCACNETDHSCKVCC
RDPSGRCVPYVDAEQKNLFLRKGKPCTVGFCDMNGKCEKRVQDVIERFWDFIDQLSINTF
GKFLADNIVGSVLVFSLIFWIPFSILVHCVDKKLDKQYESLSLFHPSNVEMLSSMDSASV
RIIKPFPAPQTPGRPQPLQVASAPPPPAAPKLEPQRMDTIQEDPSTDSHADEDGFEKDPF
PNSGTAAKSFEDLTGRPVTRSEKAASFRLQRQNRVGSKETEC
NT seq
2469 nt
NT seq
+upstream
nt +downstream
nt
atgaggcagtgtctcctcttcttgaccagcgtggttcctttcgtgctggcgccacgacct
ccgggcgattccccggagcgactcgaaaagcttgattctttactctcagactacgatatc
ctctctttatccaatatccaacagcattcagtaagaaaaagggatctacaggcctcaaca
catttagaaacactactgactttttcagccttgaaaaggcattttaaattatacctgaca
tcaagtactgaacacttttcccaaaatttcaaagtcgtggtggtagatggtaaagacgaa
agtgagtacaccgtgaaatggcaggacttcttcaggggacacgtagttggtgagcctgac
tctagagttctagcccacataggagatgatgatattacaataagaatcaacacagatggg
gcggaatataatatagagccactctggagactaattaatgatactaaagacaaaagaatt
ttagtttataaatctgaagatattaagaatgtttcacgtctacagtctccaaaagtatgt
ggttatataaaagcggataatgaagagttgcttccaaaagggctggtagacagagagcca
cctgatgagcttgttcatcgagtgaagagaagagccgagcccaatcccatgaagaacacg
tgtaaattgttggtggtagcagatcatcgcttttacagatacatgggcagaggggaagag
agtacaaccacgaattacttaatagaactcattgaccgagtggatgacatctatcggaac
acttcatgggacaacgcgggttttaaaggttatggaatacagattgagcagatccgcatt
ctcaagtctccacaagaggtgaaacccggtgaaaggcactataacatggcaaaaagttac
ccaaatgaagaaaaggatgcttgggatgtgaagatgttgctagagcaatttagttttgat
atagccgaagaagcatctaaggtctgccttgcacatcttttcacctaccaagattttgat
atgggaacccttgggttggcttatgttggttctcccagagccaacagccacggaggtgtt
tgcccaaaggcgtattatagtccaattggaaagaagaatatctatttgaatagtggcttg
accagcacaaaaaattatggtaaaaccatccttacaaaggaagctgacctggtaacaact
catgaattgggacacaattttggagcagagcatgatccggatggcctagcagaatgtgcc
ccaaatgaggaccagggaggaaaatacgttatgtatcccatcgccgtgagtggagatcat
gagaacaataagatgttctcgaactgcagtaagcagtccatctacaagaccatcgagagt
aagtcccaggagtgttttcaagagcgaagcaacaaagtgtgtgggaactccagggtggac
gaaggagaggagtgcgaccccggcatcatgtacctgaacaacgacacgtgctgcagcagc
gactgcatgctgagggccggtgtgcagtgcagtgacaggaacagcccttgctgtaaaaac
tgtcagttcgagactgcccagaagaagtgccaagaggcgatcaatgctacttgcaaaggc
gtgtcttactgcacaggtaacagcagtgagtgtcccccgcccggcaacgccgcagacgac
acagtgtgcttggatctcggcaagtgtaaagatgggaagtgtgtccccttctgtgagcgg
gagcagcagcgggagtcctgcgcgtgtaacgaaactgaccactcgtgcaaggtgtgctgc
agggacccctcgggccggtgtgtgccctacgttgacgccgaacagaagaatttattcttg
aggaaagggaagccctgtacggtgggcttctgtgacatgaatggcaagtgtgagaagcga
gtacaggacgtcatcgagcggttttgggactttatcgaccagctgagcatcaatactttt
gggaaatttttagcagacaacatcgtaggttccgtcctggttttctccttgatattttgg
atccccttcagcattcttgtccattgcgtggataagaaactggacaagcagtacgagtcc
ctgtccctgttccaccccagcaacgtggagatgctgagcagcatggactccgcctcggtg
cgcatcatcaagcccttccccgcgccccagacgcccggccgcccgcagcccctgcaggtc
gcctccgcgccgccgccccccgccgcccccaaactggagccccagagaatggacacgatc
caggaggaccccagtacggactcgcacgcggacgaggacggcttcgagaaggaccccttc
cccaacagcggcaccgctgccaagtccttcgaggacctcactggccgtccggtgacgaga
agcgagaaggccgcctcgttcaggctgcagcggcagaaccgagtgggcagcaaggagacc
gagtgctag
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