Micromonas pusilla: MICPUCDRAFT_56456
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Entry
MICPUCDRAFT_56456 CDS
T02696
Symbol
DHFR-TS
Name
(RefSeq) bifunctional dihydrofolate reductase-thymidylate synthase
KO
K13998
dihydrofolate reductase / thymidylate synthase [EC:
1.5.1.3
2.1.1.45
]
Organism
mpp
Micromonas pusilla
Pathway
mpp00240
Pyrimidine metabolism
mpp00670
One carbon pool by folate
mpp00790
Folate biosynthesis
mpp01100
Metabolic pathways
mpp01232
Nucleotide metabolism
mpp01240
Biosynthesis of cofactors
Module
mpp_M00938
Pyrimidine deoxyribonucleotide biosynthesis, UDP => dTTP
Brite
KEGG Orthology (KO) [BR:
mpp00001
]
09100 Metabolism
09104 Nucleotide metabolism
00240 Pyrimidine metabolism
MICPUCDRAFT_56456 (DHFR-TS)
09108 Metabolism of cofactors and vitamins
00790 Folate biosynthesis
MICPUCDRAFT_56456 (DHFR-TS)
00670 One carbon pool by folate
MICPUCDRAFT_56456 (DHFR-TS)
Enzymes [BR:
mpp01000
]
1. Oxidoreductases
1.5 Acting on the CH-NH group of donors
1.5.1 With NAD+ or NADP+ as acceptor
1.5.1.3 dihydrofolate reductase
MICPUCDRAFT_56456 (DHFR-TS)
2. Transferases
2.1 Transferring one-carbon groups
2.1.1 Methyltransferases
2.1.1.45 thymidylate synthase
MICPUCDRAFT_56456 (DHFR-TS)
BRITE hierarchy
SSDB
Ortholog
Paralog
GFIT
Motif
Pfam:
Thymidylat_synt
DHFR_1
Motif
Other DBs
NCBI-GeneID:
9682809
NCBI-ProteinID:
XP_003056897
JGI:
56456
UniProt:
C1MMA6
LinkDB
All DBs
Position
Unknown
AA seq
524 aa
AA seq
DB search
MSDASAPTTRPFQVVVAATKGDMGIGLDGALPWRLPKDMAYFKSVTATVAEPGKRNAVIM
GRKTWESIPAKFRPLPGRLNVVLSKSGALVESTGSENAAPANGTPSNVLPPSVLLQPSLE
AALATLGAGEHAENVEKIFVVGGAQVYAEAMASPACQAVHITEVTPPKDTPDAFKCDTHM
PPVDMEKFKLYASAPPVNEKEGAKIQFLSYVAKDAATGKFRIPGSVSLPPGAVANGVRHE
ELQYLDLIRDIIESGNVKGDRTGTGTISKFGTSMRFDLRRSFPLLTTKRVFWRGVAEELL
WFVGGRTNAKELQDKDIHIWDGNGSREYLDSVGLSHREEQDLGPVYGFQWRHFGAEYTDM
HANYDGKGVDQLAEVIDKIKNNPNDRRILLTAWNPAALKEMALPPCHMFCQFYVANGELS
CQMYQRSCDMGLGVPFNIASYSLLTCMIAQVCGLKPGDFVHVMGDTHVYSNHVEPLKKQL
LCEPRPFPTLKINPAKTDIDSFEFSDFTIEGYDPHPKIEMKMAV
NT seq
1575 nt
NT seq
+upstream
nt +downstream
nt
atgagcgacgcgagcgctcccacgacgcggccgttccaggtcgtcgtcgccgcgacgaag
ggcgacatgggcatcggcctggacggcgcgctcccgtggaggctcccgaaagacatggcg
tacttcaagtccgtgaccgcgaccgtcgcggagcccgggaagcgaaacgcggtgatcatg
ggacggaagacgtgggagtcgatcccggccaagttccggccgctccccggtcgcctcaac
gtcgtcctctcgaagtccggcgcgctcgtggagtcgaccgggtcggagaacgcggcgccg
gcgaacggcacgccgagtaacgtcctcccgccgagcgttttgttgcagccctctctcgaa
gccgcgctcgcgacgctcggcgccggcgagcacgcggaaaacgtcgaaaaaatcttcgtc
gtcggcggcgcgcaagtctacgcggaagcgatggcctcccccgcgtgccaggcggttcac
atcacggaagtcacgccgccgaaggacaccccggacgcgttcaagtgcgacacgcacatg
ccgccggtggacatggagaaattcaaactctacgcgtccgcgcccccggtgaacgaaaaa
gaaggcgcgaagattcagttcctgtcctacgtcgcgaaagacgccgccacggggaagttc
cgcatccccgggagcgtgtctctcccgcccggcgcggtcgcgaacggcgtcaggcacgag
gagctgcagtacctcgatctgatcagggacatcatcgagtctgggaacgtgaaaggcgac
cgcacgggcacggggacgatttcgaaattcggaacgtccatgcgattcgacttgcgacgg
tcgttcccgctcctcaccacgaagcgcgtgttctggcgcggcgtcgcggaggaacttctg
tggttcgtcggcgggaggacgaacgcgaaggagctccaggacaaggacatccacatctgg
gacggcaacggcagccgcgagtacctcgactccgtcgggctgtcccaccgcgaagagcaa
gacctcgggccggtgtacgggttccagtggcgacacttcggcgcggagtacacggacatg
cacgccaactacgacggcaagggcgtggaccagctcgcggaggtgatcgacaagatcaag
aacaacccgaacgaccgacgtattctgctcaccgcgtggaaccccgcggcgctgaaagag
atggcgctgcccccgtgccacatgttttgccagttttacgtcgccaacggggagctgtcg
tgtcagatgtaccagcgctcgtgcgacatgggcctcggcgtgccgttcaacatcgcgtcg
tactcgctcttgacgtgcatgatcgcgcaggtgtgcgggttaaagcccggggatttcgtg
cacgtcatgggcgacacgcacgtgtacagcaaccacgtggagccgctcaagaagcagctg
ctgtgcgagccgcggccgttcccgacgttgaagatcaatccggcgaagacggacatcgac
tcgttcgagttcagcgacttcacgatcgaggggtacgacccgcacccgaagatcgagatg
aagatggcggtgtga
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