Mycobacterium tuberculosis Erdman = ATCC 35801: ERDMAN_2281
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Entry
ERDMAN_2281 CDS
T02526
Symbol
cobI
Name
(GenBank) bifunctionalS-adenosyl-L-methionine-precorrin-2 methyltransferase/precorrin-3 methylase
KO
K13540
precorrin-2 C20-methyltransferase / precorrin-3B C17-methyltransferase [EC:
2.1.1.130
2.1.1.131
]
Organism
mtn
Mycobacterium tuberculosis Erdman = ATCC 35801
Pathway
mtn00860
Porphyrin metabolism
mtn01100
Metabolic pathways
mtn01240
Biosynthesis of cofactors
Brite
KEGG Orthology (KO) [BR:
mtn00001
]
09100 Metabolism
09108 Metabolism of cofactors and vitamins
00860 Porphyrin metabolism
ERDMAN_2281 (cobI)
Enzymes [BR:
mtn01000
]
2. Transferases
2.1 Transferring one-carbon groups
2.1.1 Methyltransferases
2.1.1.130 precorrin-2 C20-methyltransferase
ERDMAN_2281 (cobI)
2.1.1.131 precorrin-3B C17-methyltransferase
ERDMAN_2281 (cobI)
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Gene cluster
GFIT
Motif
Pfam:
TP_methylase
Motif
Other DBs
NCBI-ProteinID:
BAL66074
UniProt:
A0A0H3LEN5
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All DBs
Position
1:2319249..2320775
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AA seq
508 aa
AA seq
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MSARGTLWGVGLGPGDPELVTVKAARVIGEADVVAYHSAPHGHSIARGIAEPYLRPGQLE
EHLVYPVTTEATNHPGGYAGALEDFYADATERIATHLDAGRNVALLAEGDPLFYSSYMHL
HTRLTRRFNAVIVPGVTSVSAASAAVATPLVAGDQVLSVLPGTLPVGELTRRLADADAAV
VVKLGRSYHNVREALSASGLLGDAFYVERASTAGQRVLPAADVDETSVPYFSLAMLPGGR
RRALLTGTVAVVGLGPGDSDWMTPQSRRELAAATDLIGYRGYLDRVEVRDGQRRHPSDNT
DEPARARLACSLADQGRAVAVVSSGDPGVFAMATAVLEEAEQWPGVRVRVIPAMTAAQAV
ASRVGAPLGHDYAVISLSDRLKPWDVIAARLTAAAAADLVLAIYNPASVTRTWQVGAMRE
LLLAHRDPGIPVVIGRNVSGPVSGPNEDVRVVKLADLNPAEIDMRCLLIVGSSQTRWYSV
DSQDRVFTPRRYPEAGRATATKSSRHSD
NT seq
1527 nt
NT seq
+upstream
nt +downstream
nt
atgagcgctcggggcacgctgtggggagtcgggctggggcccggcgatccggagttggtg
accgtcaaggccgcccgggtgattggcgaggccgatgtggtggcctatcacagcgcccca
cacggtcacagcatcgcccgcggcatcgccgaaccgtatctgcggcccggtcagctcgag
gagcacctggtctacccggtgaccaccgaggccacgaatcatcccggcggctacgccggt
gcgctcgaagacttctacgccgacgcgaccgagcgcatcgccacgcacctggacgccggg
cgcaacgtggcgctgctcgccgaaggcgacccgttgttctacagctcctacatgcatctg
cacacccggctgacgcggcggttcaacgccgtcatcgtgcccggtgtgacgtcggtgagc
gccgcgtcggcggccgtggccacaccgctggtggccggcgaccaggtgttgtcggtgctg
ccgggcacgctgccggtcggcgagctgacccgccggctggccgacgccgacgcggccgtg
gtggtcaagctgggccgttcgtatcacaatgtgcgggaggcgctttcggcgtccggccta
ctcggcgacgcgttctacgtggagcgggccagcaccgccggccaacgggtattgccggcc
gccgacgtcgacgagaccagcgtgccgtacttctcgctggccatgttgccgggcgggcgg
cgtcgtgcgttgctgaccggcaccgtcgcagtggtgggcctggggcccggcgacagcgac
tggatgacaccgcagagccggcgtgagctggccgccgcgacggatctgatcggctatcgc
ggctacctggaccgggtcgaagtccgcgacggccagcggcgccatcccagcgacaacacc
gacgaacccgcccgggcgcggctggcctgctcgctggccgatcagggccgggcggtggcg
gtggtgtcctccggcgacccaggggtattcgcgatggccaccgccgttttggaggaagcc
gagcagtggccgggggtgcgggtccgggtgattccggcgatgaccgccgcccaggccgtc
gccagccgggtcggcgcgccgctgggacatgactacgcggtgatctcgttgtccgaccgg
ctcaaaccctgggacgtgatcgccgcgcgcctgaccgccgcggccgccgccgacctggtg
ctggccatctacaacccggcttcggtgacccgcacctggcaggtcggcgcgatgcgcgag
ctgctgctggcccatcgcgaccctggcataccggtggtgatcggccgcaacgtctccgga
ccggtttccggaccgaatgaggacgttcgggtggtgaagttggccgacctgaaccccgcc
gaaatcgacatgcgctgcctattgatcgtggggtcctcgcagacccggtggtattcggtg
gattcgcaggaccgggtgttcaccccgcgccgctatcccgaggcgggcagagctaccgcg
acaaagtcgagccgccacagcgactga
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