KEGG   Sciurus carolinensis (gray squirrel): 124988309
Entry
124988309         CDS       T08117                                 
Name
(RefSeq) steroid 21-hydroxylase-like isoform X1
  KO
K00513  steroid 21-monooxygenase [EC:1.14.14.16]
Organism
ncar  Sciurus carolinensis (gray squirrel)
Pathway
ncar00140  Steroid hormone biosynthesis
ncar01100  Metabolic pathways
ncar04925  Aldosterone synthesis and secretion
ncar04927  Cortisol synthesis and secretion
ncar04934  Cushing syndrome
Module
ncar_M00109  C21-Steroid hormone biosynthesis, progesterone => cortisol/cortisone
Brite
KEGG Orthology (KO) [BR:ncar00001]
 09100 Metabolism
  09103 Lipid metabolism
   00140 Steroid hormone biosynthesis
    124988309
 09150 Organismal Systems
  09152 Endocrine system
   04925 Aldosterone synthesis and secretion
    124988309
   04927 Cortisol synthesis and secretion
    124988309
 09160 Human Diseases
  09167 Endocrine and metabolic disease
   04934 Cushing syndrome
    124988309
 09180 Brite Hierarchies
  09181 Protein families: metabolism
   00199 Cytochrome P450 [BR:ncar00199]
    124988309
Enzymes [BR:ncar01000]
 1. Oxidoreductases
  1.14  Acting on paired donors, with incorporation or reduction of molecular oxygen
   1.14.14  With reduced flavin or flavoprotein as one donor, and incorporation of one atom of oxygen into the other donor
    1.14.14.16  steroid 21-monooxygenase
     124988309
Cytochrome P450 [BR:ncar00199]
 Cytochrome P450, animal type
  CYP21 family
   124988309
SSDB
Motif
Pfam: p450
Other DBs
NCBI-GeneID: 124988309
NCBI-ProteinID: XP_047413650
LinkDB
Position
7:complement(122550324..122553370)
AA seq 492 aa
MLFLGLLLLLTLLAGSRLLWGQRKLRGFHLPPHAPGFLHFLRPNLPIYLLSLTRKLGPVY
RFRLGLQDVVVLNSNRAIEEAMVRKWADFAGRPRVPSYKVVSQHYPDLSLGDYSLLWKAH
KKLVRSALLLGIRESMEPLTKQLTQEFCEHLRAQASGPVAIQKEFSFFACNIICCLIFGK
KDDTLVYAIHNCVRDVMKAWSHWSIQIVDLFPFLKFFPNPMLWKLKKIIEKRDNIVEQQL
KQHKESLVTGRWKDMIDYMLQELGRPREDSDSGQLLEGHVHMAVVDLVIGGSETMAASLS
WAVAFLLHHPEIQQRLQKELDLQLGPGASSSQILYKDRMRLPLLNATIAEVLRLRPVVPL
ALPHRTTRASSIFGYDIPEDTVVIPNLQGANLDEMVWERPEEFWPDRFLKPGKNPKVTSF
GCGARVCLGEPLARMELFVVLAHLLQAFTLLPEGTLPSLQPLTCSSLNLWMQPFQVRLQP
RVLGVPGHDQCQ
NT seq 1479 nt   +upstreamnt  +downstreamnt
atgctgttccttgggctgttgttgctactgacgctattggctggcagtcgcctgctgtgg
ggccagaggaagctcaggggcttccacctccctcctcatgccccaggcttcctgcacttc
ctgcgacccaacctccccatctatctgctcagtctcactcggaaactcgggcccgtctac
agattccgcttagggctgcaggatgttgtggtgctgaactccaacagggccattgaggag
gccatggtcagaaagtgggctgacttcgctggtagaccccgggtaccatcctacaaggtg
gtgtctcagcactatccagacctgtcactaggggactactccctcctctggaaggcccac
aagaaacttgtccgctcagccctgctactgggcatccgtgaatccatggagcccctgacg
aagcaactgacccaggagttctgtgagcacctgagagcccaggccagtggccccgtggcc
atccaaaaggaattttctttcttcgcctgtaacatcatctgctgcctcatctttggaaaa
aaggatgacaccctggtatatgccattcacaattgtgttagggatgtgatgaaagcctgg
agccactggtccatccaaattgtggacttgtttcccttcctcaagttcttccccaaccca
atgctctggaagctgaagaagatcatagaaaaaagggacaacattgtagagcagcagctg
aagcagcacaaggagagtttggtgacaggccggtggaaagacatgatagactacatgctc
caagagctggggaggccaagagaggacagtgactctggacaactccttgaagggcacgtg
cacatggccgtggtggaccttgtcattggtggcagtgaaaccatggcggcctccctctcc
tgggctgtggctttcttgcttcaccaccctgagattcagcagcgactgcagaaggagttg
gacctccaactggggcctggggcctcaagctcccagatcctatacaaggaccgaatgcgg
ctgcccttgctcaatgccaccattgcagaggtgttgcgccttcggcctgtggtgcccttg
gccttgccgcaccgcaccacccgggccagcagcatctttggctacgacatccctgaggat
acagtcgtcatccctaacctccaaggtgccaaccttgacgagatggtctgggagcgacca
gaggagttctggcctgaccgcttcctgaagcctggcaagaatcccaaagtgacatccttt
ggctgtggggcacgtgtgtgcctgggggaaccgctggcacgcatggagctcttcgtggtg
ctggcccacctgctccaggccttcacactgctgcctgagggcaccctgccctctctgcag
cccctgacctgcagtagcctgaacctctggatgcagccttttcaggtccgcctgcagccc
cgggtcctgggggtcccggggcatgaccagtgccagtga

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