Naumovozyma castellii: NCAS_0I01040
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Entry
NCAS_0I01040 CDS
T02233
Symbol
NCAS0I01040
Name
(RefSeq) L-aminoadipate-semialdehyde dehydrogenase
KO
K00143
L-2-aminoadipate reductase [EC:
1.2.1.95
]
Organism
ncs
Naumovozyma castellii
Pathway
ncs00300
Lysine biosynthesis
ncs01100
Metabolic pathways
ncs01110
Biosynthesis of secondary metabolites
ncs01230
Biosynthesis of amino acids
Module
ncs_M00030
Lysine biosynthesis, AAA pathway, 2-oxoglutarate => 2-aminoadipate => lysine
Brite
KEGG Orthology (KO) [BR:
ncs00001
]
09100 Metabolism
09105 Amino acid metabolism
00300 Lysine biosynthesis
NCAS_0I01040 (NCAS0I01040)
Enzymes [BR:
ncs01000
]
1. Oxidoreductases
1.2 Acting on the aldehyde or oxo group of donors
1.2.1 With NAD+ or NADP+ as acceptor
1.2.1.95 L-2-aminoadipate reductase
NCAS_0I01040 (NCAS0I01040)
BRITE hierarchy
SSDB
Ortholog
Paralog
Gene cluster
GFIT
Motif
Pfam:
NAD_binding_4
AMP-binding
PP-binding
Epimerase
3Beta_HSD
Condensation
NmrA
AMP-binding_C
GDP_Man_Dehyd
Polysacc_synt_2
Motif
Other DBs
NCBI-GeneID:
96905462
NCBI-ProteinID:
XP_003678117
UniProt:
G0VJU1
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Position
9:189046..193206
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AA seq
1386 aa
AA seq
DB search
MSADQIWIQKLDNPTLTVLPHDFLRPQQEPLIKQADYMLEVSQLDLSHATLTEKYTTALA
VWTALLYRLSGDDDIVLYIAENKVLRFTIQPTLSFQQLYTIIAEELTALNKISSDVSFDE
LSEKIQAQQDLEKPPQLFRLAFLKEQNESVQLNQFKHHLLDLALNLNGNILQIVYNELLY
STDRIKILADQFSQFLSTALTNPTECITKISLMTASSNSTLPDPTANLGWCDFVGCIHDI
FQDNADKFPERVCVVETPTPTNSQSRVFTYQDINRASNIVAHYLINTGIQRGDIVMIYSS
RGVDLMVCVMGVLKAGATFSVIDPAYPPARQTIYLGVAKPRGLIVIRSAGELDQLVEDYI
RDELDVISRIPSIALQDDGTIQSGGSTDVLAPFEHLKDTRSGVVVGPDSNPTLSFTSGSE
GIPKGVLGRHFSLAYYFSWMSKQFNLSSADKFTMLSGIAHDPIQRDMFTPLFLGAQLYVP
TQDDIGTPGRLAEWMGKYGCTVTHLTPAMGQLLTAQATTPFPKLHHAFFVGDILTKRDCL
RLQTLAENCCIVNMYGTTETQRAVSFFEVKSRSQDPSFLKKLKDVMPAGKGMLNVQLLVV
NRNDRTQLCGVGEVGEIYVRAGGLAEGYRGLPDLNREKFVENWFVEKGHWDHLDKDNGEP
WRQFWFGPRDRLYRTGDLGRYLPNGNCECCGRADDQVKIRGFRIELGEIDTHISQHPLVR
ENITLVRKNADNEPTLITFMVPRFDKPESLLKFQTPVPENVSSDPTVKGLIGYHLLAKDI
KIFLKKRLASYAIPSLIVVWDRLPLNPNGKVDKPKLQFPTPKQLNLVAANISSEIDDSEF
TATEREVRDLWLSILPTTPASVSPEDSFFDLGGHSILATKMIFSLKKKLNVDLPLGTIFK
YPTVKGFAIQLDAARNSKNIVADMNPLATADYAEDAKKLVETLPKSYASREPFVAPENVM
EKQIINVFVTGATGFLGSYILSEILKRSSSAYEFKVFAHVRAKDEKAALGRLEKAGITYG
TWSSDFSSNIEVVLGDLSQVNFGLSDEQWSRLTNTIDVIIHNGALVHWVYPYSKLRASNV
ISTINVMNLAASGKSKFFDFVSSTSTLDTEHYFSLSDKLSSEGKTGILESDDLQGSAYGL
GGGYGQSKWAAEYIIRRAGERGLRGCIVRPGYVTGASSNGSSNTDDFLLRFLKGSVQLGK
IPDIKNSVNMVPVDQVARVVVATALNPPKEDQLAVAHVTAHPRILFRDYLYSLKKYGYDV
EIESYEAWKKSLEESVINRNEDNALYPLLHMVLDNLPEGTKAPELDDSNAVASLKKYVSW
SGVDNSAGMGATPEQIGIYISFLNKVGFLPPASHEGTLALPKIQLSKEQIELVSSGAGAR
SSSAAA
NT seq
4161 nt
NT seq
+upstream
nt +downstream
nt
atgtctgctgaccaaatatggattcaaaagttggacaatccaacattaactgtcctacca
cacgattttttacgtcctcaacaggaaccattgatcaaacaagctgattacatgcttgaa
gtctctcaattggatctttctcacgcaactctaactgaaaaatatactactgccctcgct
gtttggactgccttactttatagactatctggtgatgacgacattgtattatatattgca
gaaaataaggtattgagatttaccattcaaccaacactatcatttcaacaattgtatacc
ataattgctgaagaattgacagcccttaataaaatttcatcagatgtctcattcgatgaa
ctttccgagaagatccaagctcaacaagatttagagaaaccacctcaattgttccgcttg
gcctttttaaaggaacaaaatgaatcggtacaattaaaccaattcaaacatcatttgcta
gatttagctctaaacttaaatgggaacatattgcaaatcgtctacaatgaattattatat
tctaccgatagaattaaaattcttgcagatcaattcagtcagtttttgtcaactgctcta
actaatcctacagaatgtataactaagatttcattaatgacagcgtcctccaactcaaca
ctaccagacccaacagccaacctaggttggtgcgatttcgttgggtgcattcatgatata
ttccaagataatgctgacaagtttcctgaaagggtttgtgttgtggaaactccaactcca
accaattctcaatcccgtgttttcacataccaagatataaatcgtgcctccaacattgtt
gcccattatttaattaatacagggattcaaagaggcgatattgtaatgatttattcatcc
cgtggagttgacttgatggtttgtgtcatgggtgtattgaaagctggggccactttctcc
gttattgatcctgcatatccacccgctagacaaactatttaccttggtgttgccaagcca
cgcgggttgattgtgattagatctgctggggaactagatcaattagtggaagattatatt
agagatgaattagatgttatttctcgtatcccatctattgcccttcaagatgatggtaca
attcaaagtggtggttcaactgatgtcctggcaccattcgaacatttaaaagatacacgc
tctggcgtcgttgtgggacctgattcaaacccaaccttatcgtttacatcaggttcagaa
ggtattcctaagggtgtccttggtagacatttttcgttagcgtattattttagctggatg
tccaaacaattcaatttatcttctgcagataaattcacaatgctaagtgggattgctcat
gatcctatccaaagagatatgtttactccattatttttaggtgctcaattatatgttcca
acacaagatgatattggtacccctggtagactggcggaatggatgggtaaatatggttgt
accgtgacacatttaacccctgcaatgggtcagctgttgaccgcacaagctacaactcca
tttcctaaattgcatcacgcatttttcgtgggagatatcctcactaaacgtgactgtctg
cgactacaaactttggcagaaaattgttgtattgttaacatgtatggtacaacagaaact
caacgtgctgtttctttctttgaagttaagtctagaagccaagatccatcgtttttaaaa
aaattgaaagatgttatgcccgctgggaaaggtatgttaaatgtgcaattattagtcgtc
aatagaaatgatcgcacacaactttgtggtgttggtgaagtcggtgaaatttatgttcgt
gctggtgggttggcagaaggttatagaggtttacctgatttgaatagggaaaaatttgtg
gaaaattggtttgtggaaaagggtcattgggatcatttggataaagataatggtgaacca
tggagacaattttggtttggacccagggatagattatacagaacaggtgatttaggtcgt
tatttaccaaacggtaattgtgaatgttgtggtcgtgctgatgatcaagttaagatccgt
gggtttagaattgaacttggtgaaattgatactcatatttctcaacatcctttagttaga
gaaaatattactttggtgcgtaaaaatgctgataatgaaccaactttgataacatttatg
gttccaagattcgacaaacctgaaagtttattgaaatttcaaactcctgttccagaaaat
gtttcatcagatccaactgttaaggggttaattggttaccatctcttagccaaggacatt
aagatatttttgaagaaaagattagcaagctacgctatcccatccttgattgttgtctgg
gacagattaccattaaatccaaacggtaaagttgataaaccaaaactacaatttccaact
ccaaaacaattaaatctagttgctgccaatatttcatctgagattgatgactctgagttc
accgccacagaacgtgaggttcgtgatttatggttgagcatattaccaactaccccagct
tctgtgtctcctgaagattcattctttgatttaggtggccactcaattctagctaccaag
atgatctttagtttgaagaagaaactaaatgttgatcttccattgggaactatttttaaa
tacccaactgtcaaaggttttgctattcagttagatgctgctagaaactccaagaatatt
gttgcagatatgaatccacttgcaactgcagattacgccgaggatgctaagaagttagtc
gaaacattgccaaaatcctatgcttctcgtgaaccatttgttgccccagaaaatgttatg
gagaaacaaatcatcaacgtttttgttacaggtgctactggtttcttaggttcctatatt
ttatctgaaatcttaaagcgttcaagttcagcatacgaattcaaagtttttgcacatgtt
cgtgcaaaagacgaaaaggcagctttaggtaggttagaaaaagcaggtattacatacggt
acatggtcttcagacttctcttctaatattgaagttgtgttgggtgatttatctcaagta
aactttggtctttctgatgaacaatggagcagattaactaatacaattgatgttatcatc
cacaatggtgctctagtacattgggtttacccatattccaagttaagagctagtaatgtt
atctccactatcaatgttatgaatcttgcagcctctggtaagtctaaattcttcgatttt
gtttcttctacctccactctagatactgaacattacttttccctctctgacaagttatct
tctgaaggtaagactggtattttggaatcagatgatttacaaggatctgcttatggtctt
ggtggtggttatggtcaatccaaatgggctgccgaatatattatcagacgtgcaggtgaa
agaggactacgtggatgcattgtaagaccaggctatgttactggtgcttcctccaatggt
tcttccaatacagatgacttcttattaagattcctaaaaggttctgtgcaacttggaaaa
atcccagatatcaagaatagcgttaacatggttccagttgatcaagtggctcgtgtggtg
gttgctacagctttaaatcctcctaaagaagatcagttagccgttgctcatgtcacagct
catccacgtatacttttcagggattatttgtattccttgaagaagtatggctacgacgtc
gaaattgaatcttacgaagcttggaagaaatccttagaagagtctgttatcaatagaaac
gaagacaacgctctttaccccctattgcatatggtacttgataatttaccagaaggtaca
aaggccccagaattagatgacagtaatgctgttgcatctttgaagaaatatgtgtcttgg
tctggtgtggataactctgcaggtatgggcgcaactccagaacaaattggcatatatatt
tcctttttaaataaggtaggattccttccacctgcaagtcatgaaggcaccttggcttta
ccaaagatccaactatctaaggaacaaattgaactagtatcttctggtgctggtgcacgt
tcaagctctgctgctgcctag
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