Nannospalax galili (Upper Galilee mountains blind mole rat): 103725890
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Entry
103725890 CDS
T03372
Name
(RefSeq) 3-alpha-hydroxysteroid dehydrogenase-like
KO
K04119
aldo-keto reductase family 1 member C3 [EC:
1.1.1.51
1.1.1.188
1.1.1.213
1.1.1.357
]
Organism
ngi
Nannospalax galili (Upper Galilee mountains blind mole rat)
Pathway
ngi00140
Steroid hormone biosynthesis
ngi00590
Arachidonic acid metabolism
ngi00790
Folate biosynthesis
ngi01100
Metabolic pathways
ngi04913
Ovarian steroidogenesis
ngi05208
Chemical carcinogenesis - reactive oxygen species
Module
ngi_M00976
C19-Steroid hormone biosynthesis, pregnenolone => testosterone => dihydrotestosterone
ngi_M00977
C19-Steroid hormone biosynthesis (androgen backdoor pathway), pregnenolone => androsterone => dihydrotestosterone
Brite
KEGG Orthology (KO) [BR:
ngi00001
]
09100 Metabolism
09103 Lipid metabolism
00140 Steroid hormone biosynthesis
103725890
00590 Arachidonic acid metabolism
103725890
09108 Metabolism of cofactors and vitamins
00790 Folate biosynthesis
103725890
09150 Organismal Systems
09152 Endocrine system
04913 Ovarian steroidogenesis
103725890
09160 Human Diseases
09161 Cancer: overview
05208 Chemical carcinogenesis - reactive oxygen species
103725890
Enzymes [BR:
ngi01000
]
1. Oxidoreductases
1.1 Acting on the CH-OH group of donors
1.1.1 With NAD+ or NADP+ as acceptor
1.1.1.51 3(or 17)beta-hydroxysteroid dehydrogenase
103725890
1.1.1.188 prostaglandin-F synthase
103725890
1.1.1.213 3alpha-hydroxysteroid 3-dehydrogenase (Re-specific)
103725890
1.1.1.357 3alpha-hydroxysteroid 3-dehydrogenase
103725890
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Motif
Pfam:
Aldo_ket_red
Thioredoxin_4
Ribul_P_3_epim
Motif
Other DBs
NCBI-GeneID:
103725890
NCBI-ProteinID:
XP_008821456
UniProt:
A0A8C6QA46
LinkDB
All DBs
Position
Un
AA seq
323 aa
AA seq
DB search
MDPSLLHVALNDGHFIPALGFGTAVPDKVPKSELIKATKIAIDAGFRHFDCAYCYQVEEE
VGMVIRSKIADGIVKREDIFYTTKLWSTFHRPELVQSALKHSLKKLQFDYVDLFLIHFPM
PLQPGDELLPRDKHGKLLFEAVDLCDTWEAMEKCKDAGLTKSIGVSNFNRRQLEMILNKP
GLKYKPVCNQVECHPYLNQGKLLDYCKSKDIVLVAYCTLGSSRDKVWVDQSSPVLLDDPV
LCAMAKKYKRSPAAIALRYQIQRGVVVLAKSFSEGRIKENMQVFDFQLTSEDMKVLDGLN
RNLRYNSADYFGGHPNHPFSDDY
NT seq
972 nt
NT seq
+upstream
nt +downstream
nt
atggatcccagcctcctgcatgtggcactaaatgatggtcacttcatccctgctctgggg
tttggaacagctgtgcctgacaaggttcctaagagtgaacttatcaaggccaccaaaata
gctatagatgctgggtttcgccattttgattgtgcttattgctaccaagtagaagaggaa
gtagggatggtcatcagaagcaagattgcagatggcattgtgaagagagaagacatattc
tatactacaaagctatggtccactttccatcgacctgaattggtccaatcagctctgaaa
cattcactgaagaaacttcaatttgactatgttgatctctttttgatccattttccaatg
cctttgcagcctggagatgaactacttccaagagataaacatggaaaattgttgtttgaa
gcagtggatctctgtgacacatgggaggccatggagaagtgtaaggacgcaggattaacc
aagtccattggggtgtccaacttcaaccgcaggcagctggagatgatcctgaacaagcca
gggctcaagtacaagcctgtgtgcaaccaggtagaatgccatccttatctcaaccagggc
aaactgctggattactgcaagtcaaaagacattgtgctggttgcttattgcactctggga
agttcacgagataaagtatgggtggaccagagctctccagttctcttggatgatccagtt
ctttgtgccatggcgaaaaagtacaagcgaagtccagctgcgattgcccttcgctaccag
attcagcgtggggttgtggtcctggccaagagttttagtgaagggaggatcaaagaaaac
atgcaggtgtttgatttccagttgacttcagaggacatgaaagtcctagatggactgaac
agaaatctaagatataattctgcagattattttggtggacacccaaaccatccattttct
gatgactattaa
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