KEGG   Nomascus leucogenys (northern white-cheeked gibbon): 100585064
Entry
100585064         CDS       T03265                                 
Symbol
CASP3
Name
(RefSeq) caspase-3 isoform X3
  KO
K02187  caspase 3 [EC:3.4.22.56]
Organism
nle  Nomascus leucogenys (northern white-cheeked gibbon)
Pathway
nle01524  Platinum drug resistance
nle04010  MAPK signaling pathway
nle04115  p53 signaling pathway
nle04148  Efferocytosis
nle04210  Apoptosis
nle04215  Apoptosis - multiple species
nle04623  Cytosolic DNA-sensing pathway
nle04650  Natural killer cell mediated cytotoxicity
nle04657  IL-17 signaling pathway
nle04668  TNF signaling pathway
nle04726  Serotonergic synapse
nle04932  Non-alcoholic fatty liver disease
nle04933  AGE-RAGE signaling pathway in diabetic complications
nle04936  Alcoholic liver disease
nle05010  Alzheimer disease
nle05012  Parkinson disease
nle05014  Amyotrophic lateral sclerosis
nle05016  Huntington disease
nle05020  Prion disease
nle05022  Pathways of neurodegeneration - multiple diseases
nle05132  Salmonella infection
nle05133  Pertussis
nle05134  Legionellosis
nle05145  Toxoplasmosis
nle05146  Amoebiasis
nle05152  Tuberculosis
nle05160  Hepatitis C
nle05161  Hepatitis B
nle05162  Measles
nle05163  Human cytomegalovirus infection
nle05164  Influenza A
nle05165  Human papillomavirus infection
nle05167  Kaposi sarcoma-associated herpesvirus infection
nle05168  Herpes simplex virus 1 infection
nle05169  Epstein-Barr virus infection
nle05170  Human immunodeficiency virus 1 infection
nle05200  Pathways in cancer
nle05203  Viral carcinogenesis
nle05205  Proteoglycans in cancer
nle05206  MicroRNAs in cancer
nle05210  Colorectal cancer
nle05222  Small cell lung cancer
nle05416  Viral myocarditis
nle05417  Lipid and atherosclerosis
Brite
KEGG Orthology (KO) [BR:nle00001]
 09130 Environmental Information Processing
  09132 Signal transduction
   04010 MAPK signaling pathway
    100585064 (CASP3)
   04668 TNF signaling pathway
    100585064 (CASP3)
 09140 Cellular Processes
  09141 Transport and catabolism
   04148 Efferocytosis
    100585064 (CASP3)
  09143 Cell growth and death
   04210 Apoptosis
    100585064 (CASP3)
   04215 Apoptosis - multiple species
    100585064 (CASP3)
   04115 p53 signaling pathway
    100585064 (CASP3)
 09150 Organismal Systems
  09151 Immune system
   04623 Cytosolic DNA-sensing pathway
    100585064 (CASP3)
   04650 Natural killer cell mediated cytotoxicity
    100585064 (CASP3)
   04657 IL-17 signaling pathway
    100585064 (CASP3)
  09156 Nervous system
   04726 Serotonergic synapse
    100585064 (CASP3)
 09160 Human Diseases
  09161 Cancer: overview
   05200 Pathways in cancer
    100585064 (CASP3)
   05206 MicroRNAs in cancer
    100585064 (CASP3)
   05205 Proteoglycans in cancer
    100585064 (CASP3)
   05203 Viral carcinogenesis
    100585064 (CASP3)
  09162 Cancer: specific types
   05210 Colorectal cancer
    100585064 (CASP3)
   05222 Small cell lung cancer
    100585064 (CASP3)
  09172 Infectious disease: viral
   05170 Human immunodeficiency virus 1 infection
    100585064 (CASP3)
   05161 Hepatitis B
    100585064 (CASP3)
   05160 Hepatitis C
    100585064 (CASP3)
   05164 Influenza A
    100585064 (CASP3)
   05162 Measles
    100585064 (CASP3)
   05168 Herpes simplex virus 1 infection
    100585064 (CASP3)
   05163 Human cytomegalovirus infection
    100585064 (CASP3)
   05167 Kaposi sarcoma-associated herpesvirus infection
    100585064 (CASP3)
   05169 Epstein-Barr virus infection
    100585064 (CASP3)
   05165 Human papillomavirus infection
    100585064 (CASP3)
  09171 Infectious disease: bacterial
   05132 Salmonella infection
    100585064 (CASP3)
   05133 Pertussis
    100585064 (CASP3)
   05134 Legionellosis
    100585064 (CASP3)
   05152 Tuberculosis
    100585064 (CASP3)
  09174 Infectious disease: parasitic
   05146 Amoebiasis
    100585064 (CASP3)
   05145 Toxoplasmosis
    100585064 (CASP3)
  09164 Neurodegenerative disease
   05010 Alzheimer disease
    100585064 (CASP3)
   05012 Parkinson disease
    100585064 (CASP3)
   05014 Amyotrophic lateral sclerosis
    100585064 (CASP3)
   05016 Huntington disease
    100585064 (CASP3)
   05020 Prion disease
    100585064 (CASP3)
   05022 Pathways of neurodegeneration - multiple diseases
    100585064 (CASP3)
  09166 Cardiovascular disease
   05417 Lipid and atherosclerosis
    100585064 (CASP3)
   05416 Viral myocarditis
    100585064 (CASP3)
  09167 Endocrine and metabolic disease
   04936 Alcoholic liver disease
    100585064 (CASP3)
   04932 Non-alcoholic fatty liver disease
    100585064 (CASP3)
   04933 AGE-RAGE signaling pathway in diabetic complications
    100585064 (CASP3)
  09176 Drug resistance: antineoplastic
   01524 Platinum drug resistance
    100585064 (CASP3)
 09180 Brite Hierarchies
  09181 Protein families: metabolism
   01002 Peptidases and inhibitors [BR:nle01002]
    100585064 (CASP3)
Enzymes [BR:nle01000]
 3. Hydrolases
  3.4  Acting on peptide bonds (peptidases)
   3.4.22  Cysteine endopeptidases
    3.4.22.56  caspase-3
     100585064 (CASP3)
Peptidases and inhibitors [BR:nle01002]
 Cysteine peptidases
  Family C14: caspase family
   100585064 (CASP3)
SSDB
Motif
Pfam: Peptidase_C14 SICA_beta
Other DBs
NCBI-GeneID: 100585064
NCBI-ProteinID: XP_003271520
Ensembl: ENSNLEG00000010895
UniProt: G1RJ33
LinkDB
Position
7b:complement(104870377..104902720)
AA seq 277 aa
MENTENSVDSKSIKNLELKIIHGSKSMDSGISLDNSYKMDYPEMGLCIIINNKNFHKSTG
MASRSGTDVDAANLRETFRNLKYEVRNKNDLTREEIVELMRDVSKEDHSKRSSFVCVLLS
HGEEGIIFGTNGPVDLRKITNFFRGDRCRSLTGKPKLFIIQACRGTELDCGIETDSGVDD
DMACHKIPVEADFLYAYSTAPGYYSWRNSKDGSWFIQSLCAMLKQYADKLEFMHILTRVN
RKVATEFESFSLDATFHAKKQIPCIVSMLTKELYFYH
NT seq 834 nt   +upstreamnt  +downstreamnt
atggagaacactgaaaactcagtggattcaaaatccattaaaaatttggaactaaagatc
atacatggaagcaaatcaatggactctggaatatccctggacaacagttataaaatggat
tatcctgagatgggtttatgtataataattaataataagaattttcataaaagcactgga
atggcatctcggtctggtacagatgtcgatgcagcaaacctcagggaaacattcagaaac
ttgaaatatgaagtcaggaataaaaatgatcttacacgggaagaaattgtggaattgatg
cgtgatgtttctaaagaagatcacagcaaaaggagcagttttgtttgtgtgcttctgagc
catggtgaagaaggaataatttttggaacaaatggacctgttgacttgagaaaaataaca
aactttttcagaggggatcgttgtagaagtctaactggaaaacccaaacttttcattatt
caggcctgccgtggtacagaactggactgtggcattgagacagacagtggtgttgatgat
gacatggcgtgtcataaaataccagtggaggcggacttcttgtatgcatactccacagca
cctggttattattcttggcgaaattcaaaggatggctcctggttcatccagtcgctttgt
gccatgctgaaacagtacgccgacaagcttgaatttatgcacattcttacccgggttaac
cgaaaggtggcaacagaatttgagtccttttcccttgatgctacttttcatgcaaagaaa
cagattccatgtattgtttccatgctcacaaaagaactctatttttatcactaa

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