Nomascus leucogenys (northern white-cheeked gibbon): 100605134
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Entry
100605134 CDS
T03265
Symbol
ADAM17
Name
(RefSeq) disintegrin and metalloproteinase domain-containing protein 17 isoform X1
KO
K06059
disintegrin and metalloproteinase domain-containing protein 17 [EC:
3.4.24.86
]
Organism
nle
Nomascus leucogenys (northern white-cheeked gibbon)
Pathway
nle04148
Efferocytosis
nle04330
Notch signaling pathway
nle04668
TNF signaling pathway
nle05010
Alzheimer disease
nle05171
Coronavirus disease - COVID-19
Brite
KEGG Orthology (KO) [BR:
nle00001
]
09130 Environmental Information Processing
09132 Signal transduction
04330 Notch signaling pathway
100605134 (ADAM17)
04668 TNF signaling pathway
100605134 (ADAM17)
09140 Cellular Processes
09141 Transport and catabolism
04148 Efferocytosis
100605134 (ADAM17)
09160 Human Diseases
09172 Infectious disease: viral
05171 Coronavirus disease - COVID-19
100605134 (ADAM17)
09164 Neurodegenerative disease
05010 Alzheimer disease
100605134 (ADAM17)
09180 Brite Hierarchies
09181 Protein families: metabolism
01002 Peptidases and inhibitors [BR:
nle01002
]
100605134 (ADAM17)
09183 Protein families: signaling and cellular processes
04090 CD molecules [BR:
nle04090
]
100605134 (ADAM17)
Enzymes [BR:
nle01000
]
3. Hydrolases
3.4 Acting on peptide bonds (peptidases)
3.4.24 Metalloendopeptidases
3.4.24.86 ADAM 17 endopeptidase
100605134 (ADAM17)
Peptidases and inhibitors [BR:
nle01002
]
Metallo peptidases
Family M12: astacin/adamalysin family
100605134 (ADAM17)
CD molecules [BR:
nle04090
]
Proteins
100605134 (ADAM17)
BRITE hierarchy
SSDB
Ortholog
Paralog
Gene cluster
GFIT
Motif
Pfam:
Reprolysin_2
Reprolysin_5
ADAM17_MPD
Disintegrin
Reprolysin_3
Reprolysin
Reprolysin_4
Pep_M12B_propep
Motif
Other DBs
NCBI-GeneID:
100605134
NCBI-ProteinID:
XP_003272766
Ensembl:
ENSNLEG00000013455
UniProt:
G1RT07
LinkDB
All DBs
Position
19:complement(9023909..9091705)
Genome browser
AA seq
824 aa
AA seq
DB search
MRQSLLFLTSVVPFVLAPRPPDDPGFGPHQRLEKLDSLLSDYDILSLSNIQQHSVRKRDL
QTSTHVETLLTFSALKRHFKLYLTSSTEHFSQNFKVVVVDGKNESEYTVKWQDFFTGHVV
GEPDSRVLAHIRDDDVIIRINTDGAEYNIEPLWRFVNDTKDKRMLVYKSEDIKNVSRLQS
PKVCGYLKVDNEELLPKGLVDREPPEELVHRVKRRADPDPMKNTCKLLVVADHRFYRYMG
RGEESTTTNYLIELIDRVDDIYRNTSWDNAGFKGYGVQIEQIRILKSPQEVKPGEKHYNM
AKSYPHEEKDAWDVKMLLEQFSFDIAEEASKVCLAHLFTYQDFDMGTLGLAYVGSPRANS
HGGVCPKAYYSPVGKKNIYLNSGLTSTKNYGKTILTKEADLVTTHELGHNFGAEHDPDGL
AECAPNEDQGGKYVMYPIAVSGDHENNKMFSNCSKQSIYKTIESKAQECFQERSNKVCGN
SRVDEGEECDPGIMYLNNDTCCNSDCTLKEGVQCSDRNSPCCKNCQFETAQKKCQEAINA
TCKGVSYCTGNSSECPPPGNAEDDTVCLDLGKCKDGKCIPFCEREQQLESCACNETDNSC
KVCCRDLSGRCVPYVDAEQKNLFLRKGKPCTVGFCDMNGKCEKRVQDVIERFWDFIDQLS
INTFGKFLADNIVGSVLVFSLIFWIPFSILVHCVDKKLDKQYESLSLFHPSNVEMLSSMD
SASVRIIKPFPAPQTPGRLQPAPVIPSAPAAPKPDHQRMDTIQEDPSTDSHVDEDGFEKD
PFPNSSTAAKSFEDLTDHPVTRSEKAASFKLQRQSRVDSKETEC
NT seq
2475 nt
NT seq
+upstream
nt +downstream
nt
atgaggcagtctctcctattcctgaccagcgtggttcctttcgtgctggcgccgcgacct
ccggacgacccgggcttcggcccccaccagagactcgagaagcttgattctttgctctca
gactacgatattctctctctatctaatatccagcagcattcggtaagaaaaagagatcta
cagacttcaacacatgtagaaacactactaactttttcagctttgaaaaggcattttaaa
ttatacctgacatcaagtactgaacatttttcacaaaatttcaaggtcgtggtggtggat
ggtaaaaatgaaagtgagtacactgtgaaatggcaggacttcttcactggacacgtggtt
ggtgagcctgactctagggttctagcccacataagagatgatgatgttataatcagaatc
aacacagatggggccgaatataacatagagccactttggagatttgttaatgataccaaa
gacaaaagaatgttagtttataaatctgaagatatcaagaatgtttcacgtttgcagtct
ccaaaagtatgtggttatttaaaagtggataatgaagagttgctcccaaaagggttagta
gacagagaaccacctgaagagcttgttcatcgagtgaagagaagagctgacccagatccc
atgaagaacacgtgtaaattattggtggtagcagatcatcgcttctacagatacatgggc
agaggggaagagagtacaactacaaattacttaatagagctaattgacagagttgatgac
atctatcggaacacttcatgggataatgcgggttttaaaggctatggagtacagatagag
cagattcgcattctcaagtctccacaagaggtaaaacctggtgaaaagcactacaatatg
gcaaaaagttacccacatgaagaaaaggatgcttgggatgtgaagatgttgctagagcaa
tttagctttgatatagctgaggaagcatctaaagtttgtttggcacaccttttcacatac
caagattttgatatgggaactcttggattagcttatgttggctctcccagagcaaacagc
catggaggtgtttgtccaaaggcttattatagcccagttgggaagaaaaatatctatttg
aatagtggtttgacgagcacaaagaattatggtaaaaccatccttacaaaggaagctgac
ctggttacaactcatgaattgggacacaattttggagcagaacatgatccggatggtcta
gcagaatgtgccccgaatgaggaccagggaggaaagtatgtcatgtatcccatagctgtg
agtggcgatcacgagaacaataagatgttttcaaactgcagtaaacaatcaatctataag
accattgaaagtaaggcccaggagtgttttcaagaacgcagcaataaagtgtgtgggaac
tcgagggtggatgaaggagaagagtgtgatcctggcatcatgtatctgaacaacgacacc
tgctgcaacagcgactgcacgttgaaggaaggtgtccagtgcagtgataggaatagtcct
tgctgtaaaaactgtcagtttgagactgcccagaagaagtgccaggaggcgattaatgct
acttgcaaaggcgtgtcctactgcacaggtaatagcagtgagtgcccgcctccgggaaat
gctgaagatgacactgtttgcttggatcttggcaagtgtaaggatgggaaatgcatccct
ttctgcgagagggaacagcagctggagtcctgtgcgtgtaatgaaactgacaactcttgc
aaggtgtgctgcagggacctttctggccgctgtgtgccctacgtcgatgctgaacaaaag
aacttatttttgaggaaaggaaagccctgtacagtaggattttgtgacatgaatggcaaa
tgtgagaaacgagtacaggatgtaattgaacgattctgggatttcattgaccagctaagc
atcaatacttttggaaagtttttagcagacaacatcgttgggtctgtcctggttttctcc
ttgatattttggattcctttcagcattcttgtccattgtgtggataagaaattggataag
cagtatgaatctctgtctctgtttcaccccagtaatgttgaaatgctgagcagcatggat
tccgcatcggttcgcattatcaaaccctttcctgcgccccagactccaggccgcctgcag
cctgcccctgtgatcccttcggcgccagcagctccaaaaccggaccaccagagaatggac
accatccaggaagaccctagcacagactcacatgtggacgaggatgggtttgagaaggac
cccttcccaaatagcagcacagccgccaagtcatttgaggatctcacggaccatccggtc
accagaagtgaaaaggctgcctcctttaaactgcagcgtcagagtcgtgttgatagcaaa
gagacagagtgctaa
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