Neomonachus schauinslandi (Hawaiian monk seal): 110576077
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Entry
110576077 CDS
T08474
Symbol
TH
Name
(RefSeq) tyrosine 3-monooxygenase isoform X1
KO
K00501
tyrosine 3-monooxygenase [EC:
1.14.16.2
]
Organism
nsu
Neomonachus schauinslandi (Hawaiian monk seal)
Pathway
nsu00350
Tyrosine metabolism
nsu00790
Folate biosynthesis
nsu01100
Metabolic pathways
nsu04728
Dopaminergic synapse
nsu04917
Prolactin signaling pathway
nsu05012
Parkinson disease
nsu05030
Cocaine addiction
nsu05031
Amphetamine addiction
nsu05034
Alcoholism
Module
nsu_M00042
Catecholamine biosynthesis, tyrosine => dopamine => noradrenaline => adrenaline
Brite
KEGG Orthology (KO) [BR:
nsu00001
]
09100 Metabolism
09105 Amino acid metabolism
00350 Tyrosine metabolism
110576077 (TH)
09108 Metabolism of cofactors and vitamins
00790 Folate biosynthesis
110576077 (TH)
09150 Organismal Systems
09152 Endocrine system
04917 Prolactin signaling pathway
110576077 (TH)
09156 Nervous system
04728 Dopaminergic synapse
110576077 (TH)
09160 Human Diseases
09164 Neurodegenerative disease
05012 Parkinson disease
110576077 (TH)
09165 Substance dependence
05030 Cocaine addiction
110576077 (TH)
05031 Amphetamine addiction
110576077 (TH)
05034 Alcoholism
110576077 (TH)
Enzymes [BR:
nsu01000
]
1. Oxidoreductases
1.14 Acting on paired donors, with incorporation or reduction of molecular oxygen
1.14.16 With reduced pteridine as one donor, and incorporation of one atom of oxygen into the other donor
1.14.16.2 tyrosine 3-monooxygenase
110576077 (TH)
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GFIT
Motif
Pfam:
Biopterin_H
TH_ACT
TOH_N
LTP_2
Motif
Other DBs
NCBI-GeneID:
110576077
NCBI-ProteinID:
XP_044775419
EnsemblRapid:
ENSNSCG00000007866
UniProt:
A0A8M1MXG3
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Position
11:complement(1759938..1767930)
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AA seq
525 aa
AA seq
DB search
MPTPSSASPQAKGFRRAVSELDAKQAEAIMVRGLLGPPSLAGAPRPGAAALLSGRVLSPQ
SPRFIGRRQSLIEDARKEREKAEAASAASSEPGDPLEAAVFKDKDGKAMLNLLFTLRGTK
TASLSRAVKAFETFEAQIHHLETRPAQKPRAGGPHLEYFVRCEVPSADLPALLSSVRRVA
EDVRGAGENKVLWFPRKVSELDKCHHLVTKFDPDLDLDHPGFSDQAYRQRRKLIAEIAFQ
YKHGDPIPRVEYTAEEIATWKEVYATLKGLYATHACREHLEAFQLLERFSGYREDSIPQL
EDVSRFLKERTGFQLRPVAGLLSARDFLASLAFRVFQCTQYIRHASSPMHSPEPDCCHEL
LGHVPMLADRTFAQFSQDIGLASLGASDEEIEKLSTLYWFTVEFGLCKQNGEVKAYGAGL
LSSYGELLHSLSEEPEIRAFDPDAAAVQPYQDQTYQSVYFVSESFSDAKDKLRNYASRIQ
RPFSVKFDPYTLAIDVLDSPHAIRRSLEGVQDELHTLTHALSAIS
NT seq
1578 nt
NT seq
+upstream
nt +downstream
nt
atgcccactcccagctctgcctcgccccaggccaagggcttccgcagggcggtctccgag
ctggatgccaagcaggccgaagccatcatggtaagggggctgctgggcccacccagcctt
gcaggtgctccccgacccggggctgcagccctgctctctgggcgtgtcctgtccccgcag
tctccgcgcttcatcgggcggcgacagagcctcatcgaggacgctcgcaaggagagagag
aaggccgaggccgcgtcggccgcctcctcggagcccggggaccccctagaggccgcagtg
ttcaaggacaaggatgggaaggccatgctgaatctgctcttcaccctccggggcaccaag
accgcgtcactgtcccgggccgtgaaggcatttgagacgtttgaagcccaaatccaccat
ctggagacccggcccgcccagaagccacgggcagggggcccccacctggagtactttgtg
cgctgtgaggtgcccagtgccgacctgcccgccctgctcagctccgtgcgccgggtggcg
gaggacgtgcgtggcgctggggagaacaaggtcctctggttcccgaggaaagtttctgag
ctggacaagtgtcaccatctggtcaccaagtttgaccctgacctggacttggatcatccg
ggcttctcggaccaggcttaccgccagcgccggaagctgatcgcggagattgcattccag
tacaagcacggtgaccctattccccgtgtggagtacacggccgaggagattgccacctgg
aaggaggtctacgccaccctcaagggcctctacgccacccacgcctgccgggagcacctg
gaggccttccagctgctggagcgcttcagcggctaccgggaggacagcatcccccagctg
gaggacgtgtcccgcttcctgaaggagcgcacgggcttccagctgcggcccgtggccggc
ctgctgtccgcccgggacttcctggccagcctggccttccgcgtgttccagtgcacccag
tacatccgacatgcgtcctcgcccatgcactcccccgagccggactgttgccatgagctg
ctggggcacgtgcccatgctggccgaccggacctttgctcagttctcccaggacatcggg
ctcgcgtccttgggggcttctgacgaggaaatcgagaagctgtccacgctgtactggttc
acggtggagttcgggctgtgtaagcagaatggcgaggtgaaggcctacggcgctgggctg
ctgtcctcctacggggagctcctgcactccctgtctgaggagcctgagatccgggccttc
gacccggatgctgccgccgtgcagccctaccaggaccagacctaccagtccgtgtacttt
gtgtccgaaagcttcagcgatgccaaggacaagctcaggaactacgcttcccgcatccaa
cgccccttctccgtgaagtttgacccgtataccttggccatcgacgtgctggacagtccc
cacgcgatccggcgctccctggagggcgtccaggatgagctgcacaccctcacccatgcg
ctgagcgccatcagctag
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