Ornithorhynchus anatinus (platypus): 100087105 Help Entry 100087105         CDS       T01045                                  Symbol CASP3 Name (RefSeq) caspase-3   KO K02187   caspase 3 [EC:3.4.22.56] Organism oaa  Ornithorhynchus anatinus (platypus) Pathway oaa01524   Platinum drug resistance oaa04010   MAPK signaling pathway oaa04115   p53 signaling pathway oaa04148   Efferocytosis oaa04210   Apoptosis oaa04215   Apoptosis - multiple species oaa04623   Cytosolic DNA-sensing pathway oaa04650   Natural killer cell mediated cytotoxicity oaa04657   IL-17 signaling pathway oaa04668   TNF signaling pathway oaa04726   Serotonergic synapse oaa04932   Non-alcoholic fatty liver disease oaa04933   AGE-RAGE signaling pathway in diabetic complications oaa04936   Alcoholic liver disease oaa05010   Alzheimer disease oaa05012   Parkinson disease oaa05014   Amyotrophic lateral sclerosis oaa05016   Huntington disease oaa05020   Prion disease oaa05022   Pathways of neurodegeneration - multiple diseases oaa05132   Salmonella infection oaa05133   Pertussis oaa05134   Legionellosis oaa05145   Toxoplasmosis oaa05146   Amoebiasis oaa05152   Tuberculosis oaa05160   Hepatitis C oaa05161   Hepatitis B oaa05162   Measles oaa05163   Human cytomegalovirus infection oaa05164   Influenza A oaa05165   Human papillomavirus infection oaa05167   Kaposi sarcoma-associated herpesvirus infection oaa05168   Herpes simplex virus 1 infection oaa05169   Epstein-Barr virus infection oaa05170   Human immunodeficiency virus 1 infection oaa05200   Pathways in cancer oaa05203   Viral carcinogenesis oaa05205   Proteoglycans in cancer oaa05206   MicroRNAs in cancer oaa05210   Colorectal cancer oaa05222   Small cell lung cancer oaa05416   Viral myocarditis oaa05417   Lipid and atherosclerosis Brite KEGG Orthology (KO) [BR:oaa00001]  09130 Environmental Information Processing   09132 Signal transduction    04010 MAPK signaling pathway     100087105 (CASP3)    04668 TNF signaling pathway     100087105 (CASP3)  09140 Cellular Processes   09141 Transport and catabolism    04148 Efferocytosis     100087105 (CASP3)   09143 Cell growth and death    04210 Apoptosis     100087105 (CASP3)    04215 Apoptosis - multiple species     100087105 (CASP3)    04115 p53 signaling pathway     100087105 (CASP3)  09150 Organismal Systems   09151 Immune system    04623 Cytosolic DNA-sensing pathway     100087105 (CASP3)    04650 Natural killer cell mediated cytotoxicity     100087105 (CASP3)    04657 IL-17 signaling pathway     100087105 (CASP3)   09156 Nervous system    04726 Serotonergic synapse     100087105 (CASP3)  09160 Human Diseases   09161 Cancer: overview    05200 Pathways in cancer     100087105 (CASP3)    05206 MicroRNAs in cancer     100087105 (CASP3)    05205 Proteoglycans in cancer     100087105 (CASP3)    05203 Viral carcinogenesis     100087105 (CASP3)   09162 Cancer: specific types    05210 Colorectal cancer     100087105 (CASP3)    05222 Small cell lung cancer     100087105 (CASP3)   09172 Infectious disease: viral    05170 Human immunodeficiency virus 1 infection     100087105 (CASP3)    05161 Hepatitis B     100087105 (CASP3)    05160 Hepatitis C     100087105 (CASP3)    05164 Influenza A     100087105 (CASP3)    05162 Measles     100087105 (CASP3)    05168 Herpes simplex virus 1 infection     100087105 (CASP3)    05163 Human cytomegalovirus infection     100087105 (CASP3)    05167 Kaposi sarcoma-associated herpesvirus infection     100087105 (CASP3)    05169 Epstein-Barr virus infection     100087105 (CASP3)    05165 Human papillomavirus infection     100087105 (CASP3)   09171 Infectious disease: bacterial    05132 Salmonella infection     100087105 (CASP3)    05133 Pertussis     100087105 (CASP3)    05134 Legionellosis     100087105 (CASP3)    05152 Tuberculosis     100087105 (CASP3)   09174 Infectious disease: parasitic    05146 Amoebiasis     100087105 (CASP3)    05145 Toxoplasmosis     100087105 (CASP3)   09164 Neurodegenerative disease    05010 Alzheimer disease     100087105 (CASP3)    05012 Parkinson disease     100087105 (CASP3)    05014 Amyotrophic lateral sclerosis     100087105 (CASP3)    05016 Huntington disease     100087105 (CASP3)    05020 Prion disease     100087105 (CASP3)    05022 Pathways of neurodegeneration - multiple diseases     100087105 (CASP3)   09166 Cardiovascular disease    05417 Lipid and atherosclerosis     100087105 (CASP3)    05416 Viral myocarditis     100087105 (CASP3)   09167 Endocrine and metabolic disease    04936 Alcoholic liver disease     100087105 (CASP3)    04932 Non-alcoholic fatty liver disease     100087105 (CASP3)    04933 AGE-RAGE signaling pathway in diabetic complications     100087105 (CASP3)   09176 Drug resistance: antineoplastic    01524 Platinum drug resistance     100087105 (CASP3)  09180 Brite Hierarchies   09181 Protein families: metabolism    01002 Peptidases and inhibitors [BR:oaa01002]     100087105 (CASP3) Enzymes [BR:oaa01000]  3. Hydrolases   3.4  Acting on peptide bonds (peptidases)    3.4.22  Cysteine endopeptidases     3.4.22.56  caspase-3      100087105 (CASP3) Peptidases and inhibitors [BR:oaa01002]  Cysteine peptidases   Family C14: caspase family    100087105 (CASP3) BRITE hierarchy SSDB OrthologParalogGene clusterGFIT Motif Pfam:  Peptidase_C14 Motif Other DBs NCBI-GeneID:  100087105 NCBI-ProteinID:  XP_028932478 Ensembl:  ENSOANG00000039253 UniProt:  A0A6I8NMY8 LinkDB All DBs Position 12:1665110..1686949 Genome browser AA seq 285 aa AA seqDB search MAAPQVEGGAASGEVMVDSKSFHSSQGKVPGKQFLGSSASLDDRYRMDYPNMGICLIINN KNFHPDTRMGCRSGTDVDAASLRDTFKKLKYEVRCKNDLKRREILELLTSVAHEDHSKRS SFVCVLLSHGEEGVIFGTDGSLELKSLASLFRGDNCRSLVGKPKLFIVQACRGTELDSGV EADSSSADDGSEQKIPVEADFLYAYSTAPGYYSWRNSMNGSWFIQALCAMLKQHAHTLEL LHILTRVNRKVATEFESYSLDATFNAKKQIPCIVSMLTKELYFPY NT seq 858 nt NT seq  +upstreamnt  +downstreamnt atggcggccccccaggtggagggaggagcggcgtcgggcgaggtgatggtcgactcaaaa tccttccacagctcacaggggaaggtgcccgggaagcagttcctggggtcctcagcctcg ctggacgacaggtacaggatggattacccaaacatggggatatgtttaatcatcaacaac aagaacttccacccagacacaagaatgggctgtcggtccggcacagacgtggacgccgcc agcctcagagacactttcaagaagctgaaatacgaagtcaggtgtaaaaacgacctgaaa aggcgtgagattctggagttactcacctccgttgcccacgaggaccacagcaagaggagc agttttgtgtgtgtgctgctaagccacggggaagaaggagtgattttcgggaccgacggc tctctggagctgaagagcttagcgagcctcttccgaggggacaactgccgaagtctggtg gggaagcccaaactcttcatcgtccaggcctgtcggggcaccgagttggacagcggcgtc gaggcggacagctccagcgcagacgacggatcggagcagaaaatccccgtcgaggccgac ttcctgtacgcgtattctacggcccccggctactattcttggcgtaactccatgaacggc tcctggttcatccaggcgctgtgcgcgatgctcaagcaacacgctcacaccctggagctc ctccacatcctcacccgcgtgaaccggaaggtggccaccgagttcgagtcgtattccctg gacgccacgttcaacgcaaagaagcagattccgtgcatcgtgtccatgctcaccaaggag ctctactttccttactga

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