KEGG   Ovis aries (sheep): 101109111
Entry
101109111         CDS       T03117                                 
Name
(RefSeq) dihydrodiol dehydrogenase 3 isoform X1
  KO
K04119  aldo-keto reductase family 1 member C3 [EC:1.1.1.51 1.1.1.188 1.1.1.213 1.1.1.357]
Organism
oas  Ovis aries (sheep)
Pathway
oas00140  Steroid hormone biosynthesis
oas00590  Arachidonic acid metabolism
oas00790  Folate biosynthesis
oas01100  Metabolic pathways
oas04913  Ovarian steroidogenesis
oas05208  Chemical carcinogenesis - reactive oxygen species
Module
oas_M00976  C19-Steroid hormone biosynthesis, pregnenolone => testosterone => dihydrotestosterone
oas_M00977  C19-Steroid hormone biosynthesis (androgen backdoor pathway), pregnenolone => androsterone => dihydrotestosterone
Brite
KEGG Orthology (KO) [BR:oas00001]
 09100 Metabolism
  09103 Lipid metabolism
   00140 Steroid hormone biosynthesis
    101109111
   00590 Arachidonic acid metabolism
    101109111
  09108 Metabolism of cofactors and vitamins
   00790 Folate biosynthesis
    101109111
 09150 Organismal Systems
  09152 Endocrine system
   04913 Ovarian steroidogenesis
    101109111
 09160 Human Diseases
  09161 Cancer: overview
   05208 Chemical carcinogenesis - reactive oxygen species
    101109111
Enzymes [BR:oas01000]
 1. Oxidoreductases
  1.1  Acting on the CH-OH group of donors
   1.1.1  With NAD+ or NADP+ as acceptor
    1.1.1.51  3(or 17)beta-hydroxysteroid dehydrogenase
     101109111
    1.1.1.188  prostaglandin-F synthase
     101109111
    1.1.1.213  3alpha-hydroxysteroid 3-dehydrogenase (Re-specific)
     101109111
    1.1.1.357  3alpha-hydroxysteroid 3-dehydrogenase
     101109111
SSDB
Motif
Pfam: Aldo_ket_red
Other DBs
NCBI-GeneID: 101109111
NCBI-ProteinID: XP_004014369
UniProt: W5PN69
LinkDB
Position
13:43176551..43185554
AA seq 323 aa
MDPKGQRVKLNDGHFIPVLGFGTFAPPEVPKSEALEVTKFAIEVGFRHIDSAHLYQNEEQ
VGQAIRSKIADGTVKREDVFYTSKLWSTSLRPELVRPALEKSLNNLQLDYVDLYIIHFPV
ALKPGEALFPKDENGKPIFDSVDLCRTWEALEKCKDAGLTKSIGVSNFNHKQLEKILNKP
GLKYKPVCNQVECHPYLNQSKLLDFCKSHDIVLVAYGALGSQRIKEWVNPNLPFLLEDPV
LSAIAKKHKQTPAVVALRYQIQRGVVVLAKSYNKKRIKENIQVFDFELTPEDMKAIDGLN
RSIRYNELLLGVGHPEYPFFEEY
NT seq 972 nt   +upstreamnt  +downstreamnt
atggatcccaaaggccagcgagtgaagcttaatgatggccacttcattcccgtcctggga
tttggaacctttgcacctccagaggttcctaagagtgaagctctggaagtcaccaaattt
gctatagaggttgggttccgccatattgacagtgctcatttgtaccaaaatgaagagcag
gttggccaggccattcgaagcaagattgccgatggcactgtgaagagagaagatgtattc
tacacttcaaagctttggtccacttctcttcgtccagaattggtcagaccagccttggaa
aagtcactgaataatcttcaactggactatgtcgatctctatattattcattttccagtg
gctctgaagccaggagaggcacttttcccaaaagatgaaaatggaaaaccaatatttgac
tcagtggatctctgtcgcacgtgggaggccctggagaagtgtaaggatgcggggctgacc
aagtccatcggagtgtccaacttcaaccacaagcagctggagaagatcctgaacaagcca
gggctcaagtataagcccgtctgcaaccaggtggaatgtcacccttatctcaatcagagc
aaactgttggatttctgcaagtcacatgatattgttcttgttgcctatggtgctctggga
tcccaaagaataaaagaatgggtaaacccaaacctcccctttctcttggaggacccagtt
ctctctgccatcgccaaaaagcacaagcaaaccccagctgtggttgcccttcgctaccag
atacaacgtggggttgtggttctggccaagagttacaacaagaagcggatcaaagagaac
atacaggtgtttgactttgaactgactccagaagacatgaaagcaatcgatggcctcaac
aggagcataagatataatgagctactactgggtgttggtcaccctgagtatccatttttt
gaagaatattga

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