Ovis aries (sheep): 101117390
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Entry
101117390 CDS
T03117
Symbol
ALOX5
Name
(RefSeq) polyunsaturated fatty acid 5-lipoxygenase isoform X2
KO
K00461
arachidonate 5-lipoxygenase [EC:
1.13.11.34
]
Organism
oas
Ovis aries (sheep)
Pathway
oas00590
Arachidonic acid metabolism
oas01100
Metabolic pathways
oas04148
Efferocytosis
oas04664
Fc epsilon RI signaling pathway
oas04726
Serotonergic synapse
oas04913
Ovarian steroidogenesis
oas05145
Toxoplasmosis
Brite
KEGG Orthology (KO) [BR:
oas00001
]
09100 Metabolism
09103 Lipid metabolism
00590 Arachidonic acid metabolism
101117390 (ALOX5)
09140 Cellular Processes
09141 Transport and catabolism
04148 Efferocytosis
101117390 (ALOX5)
09150 Organismal Systems
09151 Immune system
04664 Fc epsilon RI signaling pathway
101117390 (ALOX5)
09152 Endocrine system
04913 Ovarian steroidogenesis
101117390 (ALOX5)
09156 Nervous system
04726 Serotonergic synapse
101117390 (ALOX5)
09160 Human Diseases
09174 Infectious disease: parasitic
05145 Toxoplasmosis
101117390 (ALOX5)
Enzymes [BR:
oas01000
]
1. Oxidoreductases
1.13 Acting on single donors with incorporation of molecular oxygen (oxygenases)
1.13.11 With incorporation of two atoms of oxygen
1.13.11.34 arachidonate 5-lipoxygenase
101117390 (ALOX5)
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GFIT
Motif
Pfam:
Lipoxygenase
PLAT
Motif
Other DBs
NCBI-GeneID:
101117390
NCBI-ProteinID:
XP_014959991
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Position
25:complement(43313506..43360884)
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AA seq
617 aa
AA seq
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MPSYTVTVATGSQWFAGTDDYIYLSLVGSAGCSEKHLLDKPFYNDFERGAVDSYDVTVDE
ELGDIQLIKIEKRKYWFHDDWYLKYITVKTPCGDYIEFPCYRWLSGEGEIVLRDGQAKLA
CDDQIHILKQHRRKELETRQKQYRWMEWNPGFPLSIDAKCHKDLPRDIQFDSEKGVDFVL
NYSKAMENLFINRFMHMFQSSWNDFADFEKIFVRISNTISERVMNHWQEDLMFGYQFLNG
CNPVMIQRCLKLPDNLPVTTEMVECSLERQLTLEQEVEQGNIFIVDFKLLDGIDANKTDP
CTLQFLAAPICLLYKNLANKIVPIAIQLNQVPGEENPIFLPSDAKYDWLLAKIWVRSSDF
HVHQTITHLLRTHLVSEVFGIAMYRQLPAVHPIFKLLVAHVRFTIAINTKAREQLICEYG
LFDKANATGGGGHVQMVQKAMQDLTYTSLCFPEAIKARGMDNAEDVPYYFYRDDGLLVWE
AIKTFVAEVVDIYYEGDQVVEDDQELQDFVKDVYMYGMRGKKASGFPKSIKTKEKLCEYL
TVVIFTASAQHAAVNFGQLFLGMYPEEHFIEKPVKEAMARFRKNLDSIVSVIAERNKNKK
LPYYYLSPDRIPNSVAI
NT seq
1854 nt
NT seq
+upstream
nt +downstream
nt
atgccctcctacaccgtcaccgtggccaccggcagccagtggttcgcgggcaccgacgac
tacatctacctgagcctcgtgggctccgcgggctgcagcgagaagcacctgctggacaag
cccttctacaacgacttcgagcgcggcgcggtggattcttacgacgtgacagtggatgaa
gaactgggcgacatccagctgatcaaaatcgagaagcgcaagtactggttccatgacgac
tggtacctgaagtacatcacagtgaagacaccctgtggggattacatcgagttcccctgc
taccgctggctatcgggcgagggcgagattgtcctgagagacgggcaagcgaagttggcc
tgtgatgaccaaattcacattctcaagcagcacagacgcaaagaactggaaacacggcaa
aaacagtaccgatggatggagtggaaccctggcttcccactgagcatcgatgccaaatgc
cacaaggacttaccgcgagatatccagttcgacagcgagaaaggagtggactttgttctg
aactactccaaagcgatggagaacctgttcatcaaccgcttcatgcacatgttccagtcg
tcctggaacgacttcgccgactttgagaaaatctttgtcaggatcagcaacactatttcc
gagcgggtcatgaatcactggcaggaagacctcatgtttggctaccagttcctgaacggc
tgcaaccctgtgatgatccagcgctgtctgaagctgccagacaatctgccggtgaccaca
gagatggtggagtgcagcctggagcggcagctcaccctggagcaggaggtcgagcaaggg
aacatcttcatcgtggactttaaactgttggatggcatcgatgccaacaaaacagacccc
tgcactctgcagttcctggccgcgcccatctgcttgctgtacaagaatctggccaacaag
attgtccccattgccatccagctcaaccaggtgccgggagaagagaatcccattttcctc
ccttcggatgcaaagtatgactggctgctggccaagatctgggtgcgctccagcgacttc
cacgtccaccagaccatcacccaccttctgcgcacacatctggtgtctgaggtgtttggc
atcgccatgtaccgccagctgcctgccgtgcaccccatcttcaagctcctggtggcacac
gtgcggttcaccatcgccatcaacaccaaggcccgggagcagctcatctgtgagtacggc
ctctttgacaaggccaacgccaccgggggcggcgggcatgtgcagatggtgcagaaggcc
atgcaggacctgacctacacttccctgtgcttccctgaggccatcaaggcccggggcatg
gacaacgcggaagacgtcccctactacttctaccgggacgacgggcttctggtgtgggag
gccatcaagacgttcgtggccgaggtggtggacatctactacgagggtgaccaggtggtg
gaggacgaccaggagctgcaggacttcgtgaaggacgtttatatgtacggcatgcggggc
aagaaggcctcaggcttccccaagtccatcaagaccaaggagaagctgtgtgagtacctg
accgtggtgatctttacggcctcagcccagcatgcggcggtgaacttcggccagctgttc
ctgggcatgtacccagaggaacatttcatcgagaagcccgtaaaggaggccatggcccgg
ttccgtaagaacctcgactccatcgtcagcgtgatcgccgagcgcaacaagaacaagaag
ctgccttattactacttgtccccagaccggattcccaatagcgtggccatctga
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