KEGG   Oryctolagus cuniculus (rabbit): 127488899
Entry
127488899         CDS       T03373                                 
Name
(RefSeq) steroid 21-hydroxylase-like isoform X1
  KO
K00513  steroid 21-monooxygenase [EC:1.14.14.16]
Organism
ocu  Oryctolagus cuniculus (rabbit)
Pathway
ocu00140  Steroid hormone biosynthesis
ocu01100  Metabolic pathways
ocu04925  Aldosterone synthesis and secretion
ocu04927  Cortisol synthesis and secretion
ocu04934  Cushing syndrome
Module
ocu_M00109  C21-Steroid hormone biosynthesis, progesterone => cortisol/cortisone
Brite
KEGG Orthology (KO) [BR:ocu00001]
 09100 Metabolism
  09103 Lipid metabolism
   00140 Steroid hormone biosynthesis
    127488899
 09150 Organismal Systems
  09152 Endocrine system
   04925 Aldosterone synthesis and secretion
    127488899
   04927 Cortisol synthesis and secretion
    127488899
 09160 Human Diseases
  09167 Endocrine and metabolic disease
   04934 Cushing syndrome
    127488899
 09180 Brite Hierarchies
  09181 Protein families: metabolism
   00199 Cytochrome P450 [BR:ocu00199]
    127488899
Enzymes [BR:ocu01000]
 1. Oxidoreductases
  1.14  Acting on paired donors, with incorporation or reduction of molecular oxygen
   1.14.14  With reduced flavin or flavoprotein as one donor, and incorporation of one atom of oxygen into the other donor
    1.14.14.16  steroid 21-monooxygenase
     127488899
Cytochrome P450 [BR:ocu00199]
 Cytochrome P450, animal type
  CYP21 family
   127488899
SSDB
Motif
Pfam: p450 DUF7861
Other DBs
NCBI-GeneID: 127488899
NCBI-ProteinID: XP_051695544
LinkDB
Position
Unknown
AA seq 493 aa
MLLLGLLLLLALLAAARLLWGQWKLRSLHLPPLVPGFLHLLQPNLPIYLLGLAQKFGPIY
RLRFGLQDVVVLNSKRTIEEAMIKKWVDFAGRPPAPSYKLICEHYPDLSLGDYSLLWKAH
KKLARSALLLGIHDSMEPLVEQLAQEFCERLRAQAGAPVAIQEEFSFLTCSIICSLTFGD
KEDTLVWTVYNNVQDLLKAWGHWSVQMLDMVPFLRFFPNPGVWRLKQVLEHRDRIVERQL
RRHKESLEAGRCRDMMDYMLHGVGRQREEQGPGQLVEGHVHMAVVDLFIGGTETTAITLS
WAVAFLLHHPEIQRRLQEELDLELGPDAAGSRVSYKERARLPLLNATIAEVLRLRPVVPL
ALPHRTTRPSSISGYDIPEGTVIIPNLQGAQLDETVWEQPHEFSPDRFLEPGKSPRLLAF
GCGARLCLGEPLARLELFVVLARLLQAFTLLPPAGALPSLQPLSCSGVNLLMQPFQVQLQ
PRGPGAASLGQGQ
NT seq 1482 nt   +upstreamnt  +downstreamnt
atgctgctccttgggttgctgctgctgctggccctgctggctgctgcccgcctgctgtgg
ggccagtggaagctcaggagcctccacctcccacctcttgtcccaggtttcctgcacctg
ctgcaacccaacctccccatctatctacttggcctagctcagaaattcgggccaatctat
aggctccgcttcgggctgcaagatgtggtggtgttgaacagtaagaggaccattgaggaa
gccatgatcaaaaagtgggtggactttgccggcagaccccctgcgccgagctacaagctg
atatgtgagcactacccggacctgtcgctaggggactactccctgctctggaaagcccac
aagaaactggcgcgctcggccctgctgctgggcatccacgactccatggagccgctggtg
gagcagctagcccaagagttctgcgagcgcctgagagcccaggccggcgcccccgtggcc
atccaggaagaattctctttcctcacctgcagcatcatctgttccctcaccttcggagac
aaggaggacaccttggtgtggaccgtttacaacaatgtccaggacttgctgaaggcctgg
ggccactggtccgtccaaatgttggacatggttccctttctcaggttcttccccaaccca
ggcgtgtggaggctgaagcaggtcttagagcacagggaccgcatcgtggagcggcagctg
agacggcacaaggagagcctggaggccggccggtgcagggacatgatggactacatgctc
cacggggtgggccggcagagagaggagcagggccccggacagctcgtggaaggtcacgtg
cacatggccgtggtggaccttttcattggcggcaccgagaccacggccatcaccctctcc
tgggctgtggcgttcttgcttcaccaccctgagattcaacggcggctgcaggaggagctg
gacctcgagctgggccccgatgctgcgggctcccgggtctcctacaaggaacgggcgcgg
ctgcccttgctcaatgccaccatcgcggaggtgctgcgcctgaggcccgtagtgcccttg
gccttgccgcaccgcactacacggcccagcagcatctcgggctacgacatccctgagggc
acggtcatcatccccaacctccagggcgcccagctcgacgagactgtctgggagcagccc
cacgagttctccccggaccgcttcctggagccaggcaagagccccaggctgctggctttc
ggctgcggggcgcgcttgtgcctgggagaaccgctggcgcgcctggagctcttcgtggtg
ctggcgcggctgctccaggccttcacgctgctgccgcccgcgggcgccctgccctctctg
cagccgctgtcctgcagcggcgtcaacctcctgatgcagccttttcaggtgcagctgcag
ccccgtggcccgggtgccgcgagcctgggccagggtcagtga

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