Ochotona curzoniae (black-lipped pika): 121150202
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Entry
121150202 CDS
T11174
Symbol
TH
Name
(RefSeq) tyrosine 3-monooxygenase isoform X1
KO
K00501
tyrosine 3-monooxygenase [EC:
1.14.16.2
]
Organism
ocz Ochotona curzoniae (black-lipped pika)
Pathway
ocz00350
Tyrosine metabolism
ocz00790
Folate biosynthesis
ocz01100
Metabolic pathways
ocz04728
Dopaminergic synapse
ocz04917
Prolactin signaling pathway
ocz05012
Parkinson disease
ocz05030
Cocaine addiction
ocz05031
Amphetamine addiction
ocz05034
Alcoholism
Module
ocz_M00042
Catecholamine biosynthesis, tyrosine => dopamine => noradrenaline => adrenaline
Brite
KEGG Orthology (KO) [BR:
ocz00001
]
09100 Metabolism
09105 Amino acid metabolism
00350 Tyrosine metabolism
121150202 (TH)
09108 Metabolism of cofactors and vitamins
00790 Folate biosynthesis
121150202 (TH)
09150 Organismal Systems
09152 Endocrine system
04917 Prolactin signaling pathway
121150202 (TH)
09156 Nervous system
04728 Dopaminergic synapse
121150202 (TH)
09160 Human Diseases
09164 Neurodegenerative disease
05012 Parkinson disease
121150202 (TH)
09165 Substance dependence
05030 Cocaine addiction
121150202 (TH)
05031 Amphetamine addiction
121150202 (TH)
05034 Alcoholism
121150202 (TH)
Enzymes [BR:
ocz01000
]
1. Oxidoreductases
1.14 Acting on paired donors, with incorporation or reduction of molecular oxygen
1.14.16 With reduced pteridine as one donor, and incorporation of one atom of oxygen into the other donor
1.14.16.2 tyrosine 3-monooxygenase
121150202 (TH)
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Paralog
GFIT
Motif
Pfam:
Biopterin_H
TH_ACT
TOH_N
LTP_2
Motif
Other DBs
NCBI-GeneID:
121150202
NCBI-ProteinID:
XP_040826841
LinkDB
All DBs
Position
Unknown
AA seq
523 aa
AA seq
DB search
MPTPDAAAAAPQARGFRRAVSELDAKQVEAVMVREQVEATPEWPGLPWAPLGYPAHHHAL
SPQSPRFVGRRQSLIEDARKEREAAAAAAASASEPGDALEAAAVAHKDGKAAVTLLFSLR
DARPSLSRAVKVFETFEAKIQHLETRARTGSPHLEYFVRCQVPGGDLAALLSSLRRVAED
VRSPGADKVPWFPRRVSELDQCHHLVTKFDPDLDLDHPGFSDQAYRQRRKLIADIAFQYK
HGNPIPRVEYTAEETATWKEVYSRLRGLYTTHACREYLQALELLERCSGYREDSIPQLED
VSRFLKERTGFQLRPVAGLLSARDFLASLAFRVFQCTQYIRHASSPMHSPEPDCCHELLG
HVPMLADRTFAQFSQDIGLASLGASDEAIEKLSTLYWFTVEFGLCKQNGELKAYGAGLLS
SYGELLHSLSGEPEIRAFDPDAAAVQPYQDQTYQPVYFVSESFGDAKDKLRSYASRIQRP
FSVKFDPYTLAIDVLDTPQAVRRSLEGVQDELHTLAQALSALG
NT seq
1572 nt
NT seq
+upstream
nt +downstream
nt
atgcccaccccggacgccgctgctgccgccccccaggcccggggcttccgtagggccgtg
tctgaactggacgccaagcaggtggaggccgtgatggtaagagagcaggtggaggccacc
ccagaatggccaggcttgccgtgggcacccctcggctatccagcccaccaccatgccctg
tccccacagtccccgcggttcgtgggccgacggcagagtctcatagaggatgcccggaag
gagagagaggctgcagcagcagcggcggcgtccgcctcggagcccggggatgccctggag
gccgcggcagtggcccacaaggacgggaaggcggcagtaaccctgctcttctcgctgagg
gatgccaggccctcgttgtcccgggcggtgaaggtgtttgagacatttgaggccaagatc
caacacctggagacacgggcgcggacgggcagtccccacttggaatactttgtgcgctgc
caggtgcccggcggggacctggccgccctgctcagctctctgcgccgggtggccgaggac
gtgagaagccccggggccgacaaggtcccctggttcccaagaagggtgtcagagctggac
cagtgccaccacctggtcaccaagttcgatcccgacctggatttggaccacccgggcttc
tcggaccaagcctaccgccagcgcaggaaactgattgccgacatagccttccagtacaag
cacgggaaccccatcccccgtgtggagtacacggccgaggagactgctacctggaaggag
gtgtacagccggctgcggggcctgtacaccacgcacgcctgccgcgagtacctgcaggcc
ctggagctgctggagcgctgcagcggttaccgcgaggacagcatcccgcagctggaggac
gtgtcccgcttcctgaaggagcgcacgggcttccagctgcggcccgtggccggcctgctc
tcggcccgggacttcctggctagcctggccttccgcgtgttccaatgcacccagtacatc
cgccacgcatcctcgcccatgcactcgcctgagccggactgttgccacgaactgctgggg
cacgtgcccatgctggctgaccgcaccttcgcccagttctcccaggacatcggcctggcg
tccctgggggcctcagacgaagccatcgagaagctgtccacgctctactggttcaccgtg
gagtttgggctgtgcaaacagaacggcgagctcaaggcctacggcgcggggctgctgtcc
tcctacggggagctgctgcactcgctctccggggagccggagatccgggctttcgacccc
gacgcggccgccgtgcagccctaccaggaccagacctaccagcccgtctactttgtgtcg
gagagctttggcgacgccaaggacaagctcaggagctacgcctcccgcatccagcgtccc
ttctccgtgaagttcgacccctacacgctggccatcgacgtgctggacactccccaggcc
gtccgccgctccctggagggcgtccaggatgagctgcacacgctggcccaggcgctgagt
gccctgggctag
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