Otolemur garnettii (small-eared galago): 100957987
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Entry
100957987 CDS
T07855
Symbol
TH
Name
(RefSeq) tyrosine 3-monooxygenase isoform X2
KO
K00501
tyrosine 3-monooxygenase [EC:
1.14.16.2
]
Organism
oga
Otolemur garnettii (small-eared galago)
Pathway
oga00350
Tyrosine metabolism
oga00790
Folate biosynthesis
oga01100
Metabolic pathways
oga04728
Dopaminergic synapse
oga04917
Prolactin signaling pathway
oga05012
Parkinson disease
oga05030
Cocaine addiction
oga05031
Amphetamine addiction
oga05034
Alcoholism
Module
oga_M00042
Catecholamine biosynthesis, tyrosine => dopamine => noradrenaline => adrenaline
Brite
KEGG Orthology (KO) [BR:
oga00001
]
09100 Metabolism
09105 Amino acid metabolism
00350 Tyrosine metabolism
100957987 (TH)
09108 Metabolism of cofactors and vitamins
00790 Folate biosynthesis
100957987 (TH)
09150 Organismal Systems
09152 Endocrine system
04917 Prolactin signaling pathway
100957987 (TH)
09156 Nervous system
04728 Dopaminergic synapse
100957987 (TH)
09160 Human Diseases
09164 Neurodegenerative disease
05012 Parkinson disease
100957987 (TH)
09165 Substance dependence
05030 Cocaine addiction
100957987 (TH)
05031 Amphetamine addiction
100957987 (TH)
05034 Alcoholism
100957987 (TH)
Enzymes [BR:
oga01000
]
1. Oxidoreductases
1.14 Acting on paired donors, with incorporation or reduction of molecular oxygen
1.14.16 With reduced pteridine as one donor, and incorporation of one atom of oxygen into the other donor
1.14.16.2 tyrosine 3-monooxygenase
100957987 (TH)
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SSDB
Ortholog
Paralog
GFIT
Motif
Pfam:
Biopterin_H
TH_ACT
TOH_N
LTP_2
Motif
Other DBs
NCBI-GeneID:
100957987
NCBI-ProteinID:
XP_003798419
Ensembl:
ENSOGAG00000017051
UniProt:
H0XGQ3
LinkDB
All DBs
Position
Unknown
AA seq
494 aa
AA seq
DB search
MPTPNAATPQAKGFRRAVSELDAKQAEAIMSPRFIGRRQSLIEDARKEREAAVAAAAAAS
SEPGDPLEAVVFEEKAGKAVLNLLFSLGGTKPSTLSQAVKVFETFEAKIHHLETRPARTP
GGPRLEYLVRCELPRGDLANLLRAVHRVSGDVRSPKDDKVPWFPRKASELDKCHHLVTKF
DPDLDLDHPGFSDQVYRQRRKQIADIAFQYRHGNPIPRVEYTAEEIATWREIYTRLKGLY
ATHACREYLEAFQLLERFSGYREDSIPQLEDVSRFLKERTGFQLRPVAGLLSARDFLASL
AFRVFQCTQYIRHASSPMHSPEPDCCHELLGHVPMLADRTFAQFSQDIGLASLGASDEEI
EKLSTLYWFTVEFGLCKQNGQVKAYGAGLLSSYGELLHCLSEEPEIRAFDPEAAAVQPYQ
DQAYQSVYFVSESFSDAKDKLRSYASRIQRPFSVKFDPYTLAVDVLDSPQAILHSLKGIQ
DELHTLTHALSAIS
NT seq
1485 nt
NT seq
+upstream
nt +downstream
nt
atgcccacccccaacgccgccacaccccaggccaagggcttccgaagggccgtctctgag
ctggacgccaagcaggccgaggccatcatgtccccgcggttcatcgggcggcggcagagt
ctcatcgaggatgcccgcaaggagcgggaggcagccgtggctgcggcagcagcggcctcc
tcagagcccggggaccccctggaggccgtggtgttcgaggagaaggcggggaaggcggtg
ctgaacctgctcttctccctgggaggcaccaagccctccacgctgtcccaagctgtgaag
gtgtttgagacctttgaagccaaaatccaccacctggagacacggccggcacggaccccc
ggtggcccccgcctggagtacctggtgcgctgtgagctgccccgaggtgacctggccaac
ctgctcagggccgtgcaccgagtgtcaggagacgtgcgcagccccaaggatgacaaagtc
ccctggttcccaagaaaagcgtcggagctggacaagtgtcaccacctggtcaccaagttt
gatcctgacctggacttggaccaccctggcttctcagaccaggtgtatcgccagcgcagg
aagcagatcgctgacatagccttccagtaccggcatggcaacccaattccccgtgtggag
tacactgcagaggagattgccacgtggagggagatctacaccaggctgaagggcctctac
gccacacatgcctgccgtgagtacctcgaggccttccagctgctggagcgcttcagcggc
taccgggaggacagcatcccccagctcgaggacgtctcccgcttcctgaaggagcggacg
ggcttccagctgcggccagtggccggccttctgtctgcccgtgactttctggccagcctg
gccttccgtgtgttccagtgtacccagtacatccgccacgcatcctcacccatgcactcc
cccgagccggactgctgccatgagctgctggggcatgtgcccatgctggctgaccgtacc
tttgcccagttctcccaggacattggcctcgcatcattgggggcctcagatgaggaaatc
gagaagctgtccacgctgtactggttcacagtggagtttgggctgtgcaagcagaatggg
caggtgaaggcctacggtgctgggttgctgtcctcctacggggagctcctgcactgcctg
tctgaggaacccgagatccgggcctttgaccccgaggctgcagccgtgcagccctaccaa
gaccaggcctaccagtcagtctacttcgtgtccgagagtttcagtgatgccaaggacaag
ctcaggagctatgcctcgaggattcagcgccctttctctgtaaagttcgacccctacaca
ctggctgtggatgtactggacagcccccaggccatcctacactccctgaagggcatccag
gatgagctgcacaccctcacccatgcactcagtgccatcagctag
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